ClinicalTrials.gg
RecruitingNCT07499869DiagDTMUpdated Sep 22, 2026

INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR

An interventional study of digital jaw impressions and Modjaw® records in Temporomandibular Disorders (TMD), sponsored by Centre Hospitalier Universitaire de Nice. Recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-22.

Sponsored by Centre Hospitalier Universitaire de Nice · Not applicable, Interventional, and Other

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Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 11 studies in Temporomandibular Joint Disorders with a site in France — 3 open to participants now, 3 under way, none of them phase 3. Temporomandibular Joint Disorders · France.

Started
2026
with 1 other
No phase
7 of 11
3 open now
Registered
10th of 11
by date
Lead sponsor
2 of 11
Centre Hospitalier Universitaire de Nice

Among the 11 studies in Temporomandibular Joint Disorders with a site in France, this one is one of 2 that started in 2026, is one of 7 with no phase, and was the 10th registered.

Temporomandibular Joint Disorders

591 studies on the registry are indexed under Temporomandibular Joint Disorders; 149 are open to participants now.

Browse Temporomandibular Joint Disorders studies →

Open to participants now

3 of the 11 studies in Temporomandibular Joint Disorders with a site in France are open now. Recruiting first, the newest first:

All 3 open studies →

A study can be open while its sites in France have not opened yet or have stopped. Only those recruiting at a site in France →

Who these studies take

Of the 75 Temporomandibular Joint Disorders studies recruiting now, 26 (35%) set no upper age limit and 45 (60%) stop at 75 or younger; 7 take children under 18; 23 take healthy volunteers.

This study: 18 Years and older · all sexes · no healthy volunteers.

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02

Study summary

Temporomandibular disorders (TMD) encompass all temporomandibular muscular and osteoarticular conditions.

TMD affects 31% of the adult population, with chronic, debilitating pain in 10% of cases. Clinical diagnosis remains complex, and patients are underdiagnosed, whereas early management of these disorders can prevent worsening and significant public health expenditure.

The Modjaw device, which is integrated into modern digital workflows in dental surgery-particularly for the manufacture of prostheses-could enable systematic joint diagnosis through the automatic interpretation of tracings. The validity of interpreting condylar tracings obtained via axiography (compared to MRI, considered the gold standard) for diagnosing disc displacement in the TMJ has been demonstrated. The team recently demonstrated the reproducibility of Modjaw® condylar recordings from healthy patients, as well as the reliability of the recordings. However, to date, the evaluation of this device has not focused on its added potential in terms of assisting the clinician in diagnosing disc displacement.

03

Conditions studied

  • Temporomandibular Disorders (TMD)
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • adults;
  • positive result on the validated questionnaire for the screening of disc displacement;
  • referral for an MRI scan of the TMJs for diagnostic confirmation
  • signed form
  • membership of a social security scheme

Exclusion criteria

Exclusion Criteria:

  • Patients who do not speak or understand French;
  • Pregnant women;
  • Patients who have refused an MRI scan or for whom an MRI scan is .
  • Vulnerable patients, minors, patients under guardianship or trusteeship, or those protected by law.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (estimated)

Study arms

  • Experimental
    MODJAW®

    Modjaw® record

    Other: digital jaw impressions and Modjaw® records

Interventions

  • Otherdigital jaw impressions and Modjaw® records

    * digital impressions (optical scanner available in the department); * Modjaw® recording (system available in the department) by an investigator who is unaware of the MRI results; * entry of MRI and Modjaw® data

06

What researchers measure

Primary outcomes

  1. presence of a step in reducible disc displacement (length)

    the length between the curves, which will be examined to determine their ability to distinguish between DTM1 and MRI (in mm)

    Time frame: at inclusion

  2. presence of a step in reducible disc displacement (vertical spacing)

    the vertical spacing between the curves, which will be examined to determine their ability to distinguish between DTM1 and MRI (in mm)

    Time frame: at inclusion

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Sep 2026; primary completion for Sep 2027, 11 months later.

Of 242 non-industry interventional studies with no phase under Temporomandibular Joint Disorders, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 21. This study's planned 11 months is close to that.

Counting every sponsor, half of 246 studies reached it within 10 months; a quarter within 5 and three quarters within 21.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 24, 2026
First posted
Mar 30, 2026
StartEst.
Sep 17, 2026
Primary completionEst.
Sep 1, 2027
CompletionEst.
Sep 1, 2028
Last update
Sep 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07499869
Responsible party
Sponsor
First posted
Mar 30, 2026
Start date
Sep 17, 2026 (estimated)
Primary completion
Sep 1, 2027 (estimated)
Completion
Sep 1, 2028 (estimated)
Last update
Sep 22, 2026

Study contacts

Elodie EHRMANN
Contact
ehrmann.e@chu-nice.fr
33492033270
Carole CHARAVET
Contact
charavet.c@chu-nice.fr
33492033270

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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