Spinal Stenosis clinical trials
The registry lists 458 studies for Spinal Stenosis across more than 10 countries. 105 are recruiting or about to start. 307 of them are mainly about Spinal Stenosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
Get an email when these change. Save the Spinal Stenosis studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Seoul National University Hospital (12) · Peking University Third Hospital (10) · Yonsei University (9) · Marmara University (8) · Assiut University (6) · University Hospital, Basel, Switzerland (6) · Vertos Medical, Inc. (6) · Hospital for Special Surgery, New York (5)
What is being tested here
Drugs under test in Spinal Stenosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Methylprednisolone Acetate | 1 | 1 | 2 |
| Methylprednisolone | 1 | 1 | 2 |
| Liposomal Bupivacaine | 1 | 0 | 2 |
| Bupivacaine | 1 | 0 | 2 |
| Metaxalone | 1 | 0 | 1 |
| EC5026 | 1 | 0 | 1 |
| Propofol | 1 | 0 | 1 |
| Lidocaine | 1 | 0 | 1 |
| Ketamine | 1 | 1 | 1 |
| Vancomycin | 1 | 0 | 1 |
Drug classes tested here Local anesthetics 2 open · Corticosteroids 1 open · Opioids 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Effect of Ketamine on Intraoperative Motor Evoked Potentials · Phase 3 · University of California, San Francisco
- Dec 2026Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression · Phase 3 · Hospital for Special Surgery, New York
- Jun 2027Home-based Cycling for People With Lumbar Spinal Stenosis · Phase 3 · Assistance Publique - Hôpitaux de Paris
- Nov 2026Hybrid vs Fluoroscopy-Guided Interlaminar Epidural Injection in Lumbar Spinal Stenosis · Marmara University
- Nov 2026Crenel Lateral Interbody Fusion Combined With Lateral Plate Fixation for LSS Combined With Lumbar Instability · Second Affiliated Hospital, School of Medicine, Zhejiang University
- Nov 2026Effectiveness and Safety of the Facet Fixation (FFX®) Implant in the Treatment of Degenerative Lumbar Spinal Stenosis · SC Medica
- Nov 2026Precision Treatment of Lumbar Spine Surgery Through Advanced Nerve Root Blockade · University of Aarhus
- Nov 2026Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions. · Primus Pharmaceuticals
- Dec 2026MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study · Stryker Instruments
- Dec 2026Prediction of TEI Success in Sciatica · Eduard Verheijen
Who these studies take
Of the 66 Spinal Stenosis studies recruiting now, 30 (45%) set no upper age limit and 9 (14%) stop at 75 or younger. 2 (3%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (3%) | 2 (3%) |
| 18 | 43 (65%) | 43 (65%) |
| 30 | 50 (76%) | 50 (76%) |
| 40 | 53 (80%) | 53 (80%) |
| 50 | 63 (95%) | 63 (95%) |
| 65 | 65 (98%) | 65 (98%) |
| 75 | 61 (92%) | 61 (92%) |
| 85 | 45 (68%) | 45 (68%) |
Across all 458 studies, recruiting or not: 15% stop at 75 or younger and 5% at 65; 5% take children; 0% are for women only and 0% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Spinal Stenosis studies take
Of 123 interventional studies with no phase under Spinal Stenosis, half reached primary completion within 30 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 30 mo12–50 · 123 studies | — | 30 mo11–46 · 105 studies |
| Observational | 51 mo23–84 · 78 studies | — | 43 mo21–84 · 62 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Surgical Treatment of Adjacent Segment StenosisOct 27, 2026NCT07661199
- Activity Post Spinal Surgery Engagement TrialOct 22, 2026NCT07825480
Newly registered1
- Nurse-Led Early Standing Exercise After Lumbar Fusion in Older AdultsOct 13, 2026NCT07870993
Studies
Recruiting first, then most recently updated. Showing 50 of 458. Browse all 458 → or search them.
- Foraminal Imaging and Symptoms in Single-Level Degenerative Lumbar StenosisNot yet recruitingNCT079179621 country
- MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims StudyRecruitingNCT030729271 country
- Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman DeviceRecruitingNCT06355791Not applicable1 country
- Thoracic-Lumbar Arthrodesis- Implanet JazzRecruitingNCT053661401 country
- Surgical Treatment of Adjacent Segment StenosisRecruitingNCT07661199Not applicable1 country
- OssDsign® Spine Registry Study ("Propel")RecruitingNCT053291291 country
- Activity Post Spinal Surgery Engagement TrialRecruitingNCT07825480Not applicable1 country
- Kore Fiber PLF StudyNot yet recruitingNCT07868510Not applicable1 country
- Sarcopenia and Interlaminar Epidural Steroid Injection Outcomes in Lumbar Spinal StenosisRecruitingNCT078554191 country
- Neuropathic Pain Severity and Its Association With Radiological Findings in Lumbar Spinal StenosisRecruitingNCT078554451 country
- Vertebropexy - Randomized-controlled TrialRecruitingNCT06024785Not applicable1 country
- Combined Analysis of Retrospective and Prospective Data From Patients Who Underwent Facet Arthroplasty With the TOPS™ System or the TOPS + Versalink™ Fixation System at a Single Center.Not yet recruitingNCT078453441 country
- Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic SurgeryRecruitingNCT07837427Not applicable1 country
- Cytokines, Neuroplasticity Modulators, and Biomarkers in Spinal Canal Stenosis and Endoscopic DecompressionRecruitingNCT07232836Not applicable1 country
- Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.RecruitingNCT06157177Phase 41 country
- Study of Correlation Between the Level of Intradiscal Periostin Expression and Pfirrmann GradingRecruitingNCT077763661 country
- VR-Cognitive Behavioral Therapy Prehabilitation for Spinal Deformity SurgeryNot yet recruitingNCT07777679Not applicable1 country
- Prospective Study of ProteiOS in Lumbar Interbody Fusion (TLIF)Not yet recruitingNCT07775729Not applicable
- CGM-Based Glycemic Analysis After ESINot yet recruitingNCT072807801 country
- CLE-PAD : Prevalence of PAD in Patients With Surgically Lumbar Spinal StenosisRecruitingNCT07469020Not applicable1 country
- Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal StenosisRecruitingNCT05786313Not applicable1 country
- Correlation Between Parameters and Prognosis of Cervical Single Open-door SurgeryRecruitingNCT05767164Not applicable1 country
- Researching the Useful of Barb Suture in Obese Patients Undergoing Posterior Cervical SurgeryRecruitingNCT05895968Not applicable1 country
- Lumbosacral Spinal Stenosis - Non-Invasive Postural Therapy for Older Adult VeteransRecruitingNCT06089746Not applicable1 country
- 124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel SyndromeEnrolling by invitationNCT06907849Phase 21 country
- Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord InjuryRecruitingNCT06438471Phase 11 country
- Pulse-Width ModulationRecruitingNCT06120231Not applicable1 country
- Effect of Obesity Phenotype on Intraabdominal Pressure and Bleeding in Major Lumbar Spinal SurgeryNot yet recruitingNCT07688265
- The Lumbar Adjacent Segment Stenosis TrialNot yet recruitingNCT07670533Not applicable1 country
- Role of Intraoperative Computed Tomography in Assessment of Spine Instability in Lumbar Degenerative DiseaseNot yet recruitingNCT076445071 country
- Evaluation of the Evolution of Patient Care Within the Spinal Pathology DepartmentRecruitingNCT07627282Not applicable1 country
- Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac AmyloidosisRecruitingNCT060344051 country
- Balance Amongst Patients With Lumbar Spinal StenosisRecruitingNCT060758621 country
- Activity Levels Amongst Patients With Lumbar Spinal StenosisRecruitingNCT060574281 country
- PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling MaterialsRecruitingNCT076154911 country
- Hybrid vs Fluoroscopy-Guided Interlaminar Epidural Injection in Lumbar Spinal StenosisNot yet recruitingNCT07612982Not applicable1 country
- Comparative Analysis of Two Transforaminal Lumbar Interbody Fusion (TLIF) Procedures in the Treatment of Single-Level Lumbar Spinal Stenosis (LSS): A Single-Center, Prospective, Randomized Controlled TrialRecruitingNCT07588555Not applicable1 country
- Lumbar Steroid Use in Patients Undergoing Posterior Lumbar DecompressionRecruitingNCT05058287Phase 31 country
- Clinical and MRI Findings in Lumbar Disc DiseaseNot yet recruitingNCT07516613
- Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal StenosisNot yet recruitingNCT07482826Not applicable
- Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine SurgeryRecruitingNCT074890011 country
- Study Comparing Local/ MAC Anesthesia in Lumbar DecompressionRecruitingNCT04992572Early Phase 11 country
- Presence of Dural Pulsation in Patients Diagnosed With Lumbar Spinal StenosisRecruitingNCT072337981 country
- Multicentric Case Series of Uniportal Endoscopic Posterior Cervical Decompression for Cervical Spinal StenosisRecruitingNCT068868021 country
- Bilateral Lumbar Decompression Via Uniportal Endoscopic Laminotomy in Patients With Lumbar Spinal Stenosis: Multicentric Case SeriesRecruitingNCT070457141 country
- Continuous Erector Spinae Block for Analgesia Following Lumbar DecompressionNot yet recruitingNCT06987409Not applicable
- Regional Anesthesia in Minimally Invasive Lumbar Spine SurgeryRecruitingNCT05029726Phase 41 country
- Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine SurgeryEnrolling by invitationNCT051108331 country
- Gait and Paraspinal sEMG in Degenerative Spinal DiseasesNot yet recruitingNCT073099261 country
- Lumbar Interbody Implant StudyEnrolling by invitationNCT044188301 country