An observational study in Degenerative Lumbar Spinal Stenosis and Lumbar Foraminal Stenosis, sponsored by The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine. Not yet recruiting at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-11-09.
Sponsored by The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine · Observational
This retrospective observational study investigated the correlation between foraminal imaging morphology (evaluated by MRI 4-level score and CT Haleem-Botchu classification) and the severity of clinical symptoms in patients with single-level degenerative lumbar spinal stenosis. A total of 120 adult patients treated between January 2024 and December 2025 were included. Patients were categorized into mild, moderate, and severe groups based on their Visual Analog Scale (VAS) scores. The study analyzed the correlation of imaging grades with clinical functional scores (ODI and VAS) and identified independent imaging factors associated with symptom severity. No new treatments or extra hospital visits were involved.
To ensure data validity, two independent radiologists, who were blinded to the patients' clinical information and grouping, evaluated the imaging grades at the responsible segment on the symptomatic side. Inter-observer reliability was assessed using the weighted Kappa coefficient.
456 studies on the registry are indexed under Constriction, Pathologic; 109 are open to participants now.
This study's planned enrollment of 120 is above the median of 84 across 144 observational studies indexed under Constriction, Pathologic.
Browse Constriction, Pathologic studies →The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine is the lead sponsor of 11 studies on the registry; 2 are open to participants now.
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This retrospective cohort study initially screened 289 consecutive patients diagnosed with single-level degenerative lumbar spinal stenosis between January 2024 and December 2025. After applying strict inclusion and exclusion criteria, a final cohort of 151 eligible patients was established. From this cohort, a stratified sampling method was applied to select 120 patients (40 patients per group) to ensure balanced statistical power, categorizing them into mild (VAS 1-3), moderate (VAS 4-7), and severe (VAS 8-10) symptom groups based on their baseline Visual Analog Scale (VAS) scores. Clinical and imaging data were extracted for correlation and regression analysis.
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Exclusion Criteria:
Patients with a Visual Analog Scale (VAS) pain score of 1-3 (n=40). This is a retrospective observational group with no interventions.
Other: No Intervention: Observational Cohort
Patients with a Visual Analog Scale (VAS) pain score of 4-7 (n=40). This is a retrospective observational group with no interventions.
Other: No Intervention: Observational Cohort
Patients with a Visual Analog Scale (VAS) pain score of 8-10 (n=40). This is a retrospective observational group with no interventions.
Other: No Intervention: Observational Cohort
This is a retrospective observational study using existing medical records and imaging data. No treatments, drugs, or interventions were administered to the participants.
Correlation Between Imaging Grading and VAS Pain Scores
The correlation between the severity of foraminal stenosis (assessed by MRI 4-level score and CT Haleem-Botchu classification) and Visual Analog Scale (VAS) pain scores in patients with single-level degenerative lumbar spinal stenosis. The association was analyzed using the Spearman rank correlation coefficient.
Time frame: Baseline (at index imaging; single time-point cross-sectional assessment)
Correlation Between Imaging Grading and ODI Scores
The correlation between foraminal imaging morphology and Oswestry Disability Index (ODI) scores. The association was analyzed using the Spearman rank correlation coefficient.
Time frame: Baseline (at index imaging; single time-point cross-sectional assessment)
Factors Independently Associated with Symptom Severity
Multivariable ordinal logistic regression was used to identify independent imaging factors (MRI and CT grading) associated with clinical symptom severity, adjusting for baseline characteristics such as age, gender, and symptom duration.
Time frame: Baseline (at index imaging; single time-point cross-sectional assessment)
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine