Speech Disorders clinical trials
The registry lists 77 studies for Speech Disorders across more than 10 countries. 20 are recruiting or about to start. 19 of them are mainly about Speech Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-15. Counting its 6 narrower conditions too, such as Aphasia: 589 studies, 174 open.
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Who runs them
Stanford University (4) · Boston University Charles River Campus (3) · US Department of Veterans Affairs (2) · National Institutes of Health Clinical Center (CC) (2) · University of Chicago (2) · National Institute on Deafness and Other Communication Disorders (NIDCD) (2) · University of North Carolina, Chapel Hill (2) · University of Pittsburgh (2)
What is being tested here
Drugs under test in Speech Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Brimapitide | 0 | 2 | 2 |
| Rotigotine | 0 | 0 | 1 |
| Cytotoxic Agent-LAT1 Substrate QBS10072S | 0 | 0 | 1 |
| Ecopipam | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Dec 2026AI-Based Speech Intelligibility Assessment: Efficacy & Reliability · Pusan National University Yangsan Hospital
- Jan 2027Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot Study · Vanessa Torrecillas
- Aug 2027Detection of Hoarding Disorder and Related Psychopathology · Andreas Rosén Rasmussen
- Nov 2027Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia · Stephanie Grasso
Who these studies take
Of the 16 Speech Disorders studies recruiting now, 10 (63%) set no upper age limit and 5 (31%) stop at 75 or younger. 4 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (31%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (13%) | 2 (13%) |
| 18 | 12 (75%) | 12 (75%) |
| 30 | 12 (75%) | 12 (75%) |
| 40 | 13 (81%) | 13 (81%) |
| 50 | 13 (81%) | 13 (81%) |
| 65 | 12 (75%) | 12 (75%) |
| 75 | 11 (69%) | 11 (69%) |
| 85 | 10 (63%) | 10 (63%) |
Across all 77 studies, recruiting or not: 30% stop at 75 or younger and 25% at 65; 31% take children; 0% are for women only and 1% for men only; 38% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Speech Disorders studies take
Of 37 interventional studies with no phase under Speech Disorders, half reached primary completion within 28 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 28 mo17–38 · 37 studies | — | 28 mo17–38 · 35 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 77. Browse all 77 → or search them.
- Network Connectivity and Temporal Processing in Adolescents Who StutterRecruitingNCT05286151Not applicable1 country
- Wireless Implantable Mandarin Chinese Speech Neuroprosthesis EvaluationRecruitingNCT07647315Not applicable1 country
- Voiceitt for People With Impairments in SpeechRecruitingNCT06874322Not applicable1 country
- Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered SpeechRecruitingNCT07459803Not applicable1 country
- Evaluation of the Feasibility and Efficacy of a Chronic Brain-computer Interface for Speech Rehabilitation in Patients With Locked-in-syndrome (LIS)Not yet recruitingNCT07698496Not applicable1 country
- Gender Disparities in Voice Outcomes After Tracheoesophageal Puncture in Total Laryngectomy Patients (UC Davis)RecruitingNCT054899651 country
- Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment AnalysesRecruitingNCT041173601 country
- Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive AphasiaRecruitingNCT05741853Not applicable2 countries
- Speech Amplification Devices for Parkinson Disease: Talker- and Technology-Driven EnhancementsRecruitingNCT07599696Not applicable1 country
- Clinical Feasibility & Validation of the Virtual Reality GlenxRose Speech-Language TherapiesRecruitingNCT05695131Not applicable1 country
- Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot StudyRecruitingNCT07264036Not applicable1 country
- Rapid Non-Invasive Brain Stimulation for Hoarding DisorderRecruitingNCT06712914Not applicable1 country
- Detection of Hoarding Disorder and Related PsychopathologyRecruitingNCT07483021Not applicable1 country
- Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator RecipientsRecruitingNCT07455760Not applicable1 country
- AI-Based Speech Intelligibility Assessment: Efficacy & ReliabilityNot yet recruitingNCT07347782
- The Links Between Executive and Linguistic Processes and Their Lesional Determinants From a Verbal Fluency TaskRecruitingNCT05875103Not applicable1 country
- Effects of Associated Impairments on Activity and Participation in Children With Cerebral PalsyRecruitingNCT069441711 country
- TapTalkTest Project:Development of a Non-invasive Screening Test to Detect Risk of Alzheimer's Disease PathologyEnrolling by invitationNCT061149141 country
- Articulatory Adaptation Following Oral Cancer TreatmentRecruitingNCT058762471 country
- Supplementary Motor Area is a Potential Target for Speech Disturbance in Parkinson DiseaseNot yet recruitingNCT05478057Not applicable
- The Mere-measurement Effect of Patient-reported OutcomesCompletedNCT06443073Not applicable1 country
- Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered SpeechCompletedNCT05437159Not applicable1 country
- Comparison of Graded Motor Imagery and Mirror Therapy in Chronic Stroke RehabilitationCompletedNCT06980181Not applicable1 country
- The Effect of Animal-Assisted Activity Programme Based on Human Caring Theory on Perceived Stress, Social Adaptation and Communication Skills of Children With Speech and Language DisordersCompletedNCT07512180Not applicable1 country
- Neural Changes After Speech Therapy in Patients With Cleft Palate: A Brain Imaging StudyCompletedNCT07330687Not applicable1 country
- Enhancing Treatment of Hoarding Disorder With Personalized In-Home Sorting and Decluttering PracticeCompletedNCT02843308Not applicable1 country
- tACS Modulates Speech and Cognitive Impairments in People With PD by Targeting the Medial Frontal CortexCompletedNCT07240272Not applicable1 country
- In-home Decluttering Augmentation of Group CBT for HDActive, not recruitingNCT04712474Not applicable1 country
- Visual Feedback of Tongue by Ultrasound Echography for Speech Trouble RehabilitationCompletedNCT02752425Not applicable1 country
- Imaginal Exposure for Hoarding DisorderCompletedNCT03734705Not applicable1 country
- Effect of Hearing Aid Versus Cochlear Implant on Hearing and Speech Recognition in ChildrenActive, not recruitingNCT069135171 country
- An Initial Test of Prototype Mobile App Interventions for DeclutteringCompletedNCT06108245Not applicable1 country
- Dopaminergic Therapy for Frontotemporal Dementia PatientsCompletedNCT04937452Phase 21 country
- Clinical Evaluation of Florbetapir in Primary Progressive AphasiaCompletedNCT047265271 country
- Florbetaben PET Imaging in PPACompletedNCT047200011 country
- Smart Computing Models, Sensors, and Early Diagnostic Speech and Language Deficiencies Indicators in Child CommunicationCompletedNCT06633874Not applicable1 country
- MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal ImpairmentsCompletedNCT04762043Not applicable1 country
- Intensive Versus Traditional Voice TherapyCompletedNCT03129880Not applicable1 country
- Hoarding Disorder Treatment With Virtual RealityCompletedNCT03828461Not applicable1 country
- Efficacy of a Digital Therapeutic for People With Dysarthria After StrokeCompletedNCT05146765Not applicable1 country
- Real World Testing of a Brain-Computer InterfaceCompletedNCT040265811 country
- AM-111 in the Treatment of Acute Inner Ear Hearing LossCompletedNCT02561091Phase 31 country
- rTMS and Multi-Modality Aphasia Therapy for Post-Stroke AphasiaCompletedNCT04901156Not applicable1 country
- The Effect of Combined Speech and Music-therapy on the Speech Characteristics of People With Parkinson's Disease (PD)CompletedNCT04966689Not applicable1 country
- A New Membrane Obturator Prothesis Concept for Soft Palate DefectsCompletedNCT04009811Not applicable1 country
- Speeded Anomia Treatment in Chronic Post-stroke AphasiaStatus unknownNCT05512884Not applicable1 country
- Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072SCompletedNCT04430842Phase 11 country
- Personal Protective Equipment EffectsCompletedNCT053696631 country
- Intranasal Inhalations of M2 Macrophage Soluble Factors in Children With Developmental Speech DisordersCompletedNCT04689282Phase 1/21 country
- Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency BandStatus unknownNCT05339906Not applicable1 country