An interventional study of Speeded anomia therapy in Aphasia, sponsored by University of Cambridge. Status unknown at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-01-19.
Sponsored by University of Cambridge · Not applicable, Interventional, and Treatment
The main aim of the study is to investigate the effect of a novel, speeded anomia therapy (Conroy et al., 2018) in a large population of patients with chronic post-stroke aphasia. The treatment will be delivered via a web application (QuickWord).
The main aim is to test the clinical efficacy of a novel, web based, rehabilitation approach to aphasic word-finding difficulties (QuickWord). In an initial development and case-series evaluation, Conroy et al (2018, Brain) found that training for both speed as well as accuracy of naming generated much better outcomes to picture naming accuracy and also augmented the carry-over to connected speech production.
This is a randomised, crossover, clinical trial of QuickWord in a group of aphasic patients in the chronic post-stroke period. The comparison will be standard care. The main outcome measures are clinically relevant improvement in naming to confrontation, and spontaneous use of the target vocabulary in a connected speech sample (detailed picture description). Secondary outcome includes measured use of the vocabulary in a story-telling, connected speech assessment (retelling of the Cinderella story).
338 studies on the registry are indexed under Aphasia; 95 are open to participants now.
This study's planned enrollment of 100 is above the median of 30 across 298 interventional studies indexed under Aphasia.
Browse Aphasia studies →University of Cambridge is the lead sponsor of 116 studies on the registry; 23 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
21h of anomia therapy
Behavioral: Speeded anomia therapy
Participants' typical daily routine
The speeded anomia therapy was introduced as RISP (Repeated, Increasingly Speeded Production) by Conroy et al. (2018). Participants are asked to name the picture presented to them before an auditory stimulus ('beep' sound) at the end of item presentation. In each session the allotted response time is gradually reduced. After an incorrect response, participants are asked to repeat the word three times.
Speeded anomia therapy effect in reaction time
Change in reaction time in single-item picture naming
Time frame: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)
Speeded anomia therapy effect in accuracy
Change in accuracy in single-item picture naming
Time frame: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)
Generalisation to connected speech
Change in word retrieval in composite picture description. Participants will be asked to describe composite pictures (from the "Where's Waldo/Wally?" publications).
Time frame: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)
Generalisation to story-telling connected speech
Change in narrative speech production. Participants will be asked to narrate the Cinderella story. A checklist with some of the most frequently used nouns (data obtained from AphasiaBank database) will be used.
Time frame: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)
This study is status unknown, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
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