Scoliosis clinical trials
The registry lists 660 studies for Scoliosis across more than 10 countries. 186 are recruiting or about to start. 584 of them are mainly about Scoliosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
ClinicalTrials.gov finds 780 studies for Scoliosis. How that becomes 660 here
This page counts the studies the registry files under Scoliosis, and those it files under no condition that list Scoliosisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 780Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −88List Scoliosis as a condition, but the registry did not file them under itMost often written as “Adolescent Idiopathic Scoliosis” (22), “Idiopathic Scoliosis” (16), and “Scoliosis Idiopathic” (16). The registry filed them under other conditions only, most often Agnosia (12) and Pain, Postoperative (11).
- −32Match it another way27 name it in the title, 3 in a keyword, and 2 by a synonym or other text the search reads.
- 660The count on this page257 of them list Scoliosis in their own words; the registry filed them under no condition.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Status
Who runs them
The University of Hong Kong (15) · Hacettepe University (15) · Chinese University of Hong Kong (14) · Cairo University (13) · Istituto Scientifico Italiano Colonna Vertebrale (11) · The Hong Kong Polytechnic University (10) · Istanbul University - Cerrahpasa (10) · Istituto Ortopedico Rizzoli (9)
What is being tested here
Drugs under test in Scoliosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexamethasone | 1 | 0 | 4 |
| Lidocaine | 1 | 1 | 2 |
| Tegileridine | 1 | 0 | 1 |
| Aprepitant | 1 | 0 | 1 |
| Ferric carboxymaltose | 1 | 1 | 1 |
| Alfacalcidol | 1 | 0 | 1 |
| Ropivacaine | 1 | 0 | 1 |
| Dexmedetomidine | 0 | 0 | 4 |
| Methadone | 0 | 2 | 4 |
| Morphine | 0 | 1 | 3 |
Drug classes tested here Local anesthetics 2 open · Antiemetics 1 open · Opioids 8 · Antifibrinolytics 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jun 2027Safety and Efficacy Evaluation of Insight GS Growing System · Phase 3 · EVEREST PESQUISA E DESENVOLVIMENTO LTDA
- Aug 2027IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study · Phase 3 · Columbia University
- Nov 2026Effect of Core Stabilization Exercises Versus Traditional Rehabilitation in Adolescent With Idiopathic Scoliosis · Armed Forces Hospitals, Southern Region, Saudi Arabia
- Nov 2026Turkish Adaptation and Validation of the Scoliosis Misconception Scale in Adolescents With Idiopathic Scoliosis · Kahramanmaras Sutcu Imam University
- Nov 2026Protocol for a Randomized Controlled Trial of a Clinician-Supervised Home-School-Hospital-Linked Digital Health Platform-Supported Conservative Management Pathway for AIS · Hangzhou Medical College
- Dec 2026Prospective, Multi-Center Adult Spinal Deformity Outcomes Database Registry · International Spine Study Group Foundation
- Dec 2026Construction of a Screening and Precision Intervention System for Adolescent Idiopathic Scoliosis Based on the DIERS Spinal Moiré System · Jiawei Jiang
- Dec 2026Changes in Cerebral Oxygenation Related to Intraoperative Position Changes · Joseph D. Tobias
- Dec 2026Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis · University of California, San Francisco
- Dec 2026Sleep Quality in Adolescents With Idiopathic Scoliosis · Bezmialem Vakif University
Who these studies take
Of the 117 Scoliosis studies recruiting now, 23 (20%) set no upper age limit and 88 (75%) stop at 75 or younger. 98 (84%) take children under 18. 9 (8%) are for women only and 0 (0%) for men only; 14 (12%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 82 (70%) | 75 (64%) |
| 18 | 81 (69%) | 80 (68%) |
| 30 | 33 (28%) | 32 (27%) |
| 40 | 32 (27%) | 31 (26%) |
| 50 | 30 (26%) | 30 (26%) |
| 65 | 29 (25%) | 29 (25%) |
| 75 | 29 (25%) | 29 (25%) |
| 85 | 28 (24%) | 28 (24%) |
Across all 660 studies, recruiting or not: 81% stop at 75 or younger and 79% at 65; 86% take children; 8% are for women only and 1% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Scoliosis studies take
Of 19 phase 4 interventional studies under Scoliosis, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 4 | 19 mo13–37 · 19 studies | — | — |
| Interventional, no phase | 22 mo8–60 · 233 studies | — | 21 mo8–58 · 223 studies |
| Observational | 36 mo9–92 · 106 studies | — | 29 mo9–99 · 94 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
- Sleep Quality in Adolescents With Idiopathic ScoliosisOct 20, 2026NCT07767591
Studies
Recruiting first, then most recently updated. Showing 50 of 660. Browse all 660 → or search them.
- Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular AtrophyRecruitingNCT05866419Not applicable5 countries
- Tranexamic Acid in Pediatric Idiopathic Scoliosis SurgeryRecruitingNCT07581457Not applicable1 country
- Turkish Adaptation and Validation of the Scoliosis Misconception Scale in Adolescents With Idiopathic ScoliosisRecruitingNCT079091741 country
- Clinical and Biological Parameters in Adolescent Idiopathic ScoliosisNot yet recruitingNCT07900126
- Studying Melatonin and Recovery in TeensRecruitingNCT06093477Not applicable1 country
- Protocol for a Randomized Controlled Trial of a Clinician-Supervised Home-School-Hospital-Linked Digital Health Platform-Supported Conservative Management Pathway for AISRecruitingNCT06314594Not applicable1 country
- Detecting and Monitoring Scoliosis Without Radiography: Standard Radiographic Monitoring Program Versus Self-Screening With Momentum SpineTMRecruitingNCT06825611Not applicable1 country
- Scoliosis Treatment: Evaluating Patient SuitabilityNot yet recruitingNCT07891676
- Intravenous Dexamethasone for ESP Block Analgesia in Children Undergoing Idiopathic Scoliosis SurgeryNot yet recruitingNCT07890220Phase 41 country
- Effectiveness of a Horse Riding Simulator in Adolescents With Idiopathic ScoliosisRecruitingNCT07758712Not applicable1 country
- Quality of Life (HRQoL) of AIS Patients Who Require Bracing or Surgery Using SRS-22 QuestionnaireRecruitingNCT039151061 country
- Quality of Life, Psychosocial Burden, and Structural-functional Status in Adults With Spinal Deformity.RecruitingNCT07749534Not applicable1 country
- Sleep Quality in Adolescents With Idiopathic ScoliosisRecruitingNCT077675911 country
- Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic PainRecruitingNCT076025951 country
- Tegileridine for Postoperative Pain After Adolescent Scoliosis SurgeryRecruitingNCT07229495Phase 41 country
- The Effect of Curve Type Determined According to the Rigo Classification on Respiratory Muscle Strength, Quality of Life, and Functional Status in Individuals Diagnosed With Adolescent Idiopathic Scoliosis.Not yet recruitingNCT07863492
- Evaluation of Analgesia for Spine Fusion Elective Surgery in ChildrenRecruitingNCT06626503Phase 31 country
- Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.Not yet recruitingNCT07852286Not applicable1 country
- A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body TetheringRecruitingNCT04914507Not applicable2 countries
- Multicentric Evaluation of Enhanced Recovery After Surgery Protocol in Adolescent Idiopathic Scoliosis SurgeryRecruitingNCT06908213Not applicable1 country
- Effect of Treatment on Activity and Muscle Function in Pediatric Patients With ScoliosisEnrolling by invitationNCT02610855Not applicable1 country
- Investigation of Muscle Activity With sEMG, Surface Topography and Radiographic Changes of Paraspinal Muscles in Individuals With Adolescent Idiopathic Scoliosis.Not yet recruitingNCT07804836
- Clinical Orthopaedic Data Bank (Acute and Chronic)RecruitingNCT004110601 country
- Supervised vs. Home Schroth Exercise in AISRecruitingNCT07779070Not applicable1 country
- Virtual Reality-based Schroth Exercise Versus Traditional Schroth Exercise on Trunk Kinematics in ScoliosisNot yet recruitingNCT07794020Not applicable1 country
- Postoperative Rehabilitation in Adolescent Idiopathic ScoliosisNot yet recruitingNCT07791485Not applicable
- Brace Treatment for Idiopathic Scoliosis; PReventing Idiopathic SCOliosis PROgressionRecruitingNCT04805437Not applicable1 country
- Preoperative Carbohydrate Drink in Adolescent Idiopathic Scoliosis Surgery: the Impact on Safety and Enhanced RecoveryRecruitingNCT06680297Not applicable1 country
- Machine Learning Prediction of Disease Progression in Adolescent Idiopathic ScoliosisRecruitingNCT07556042Not applicable1 country
- BSPTS and Core Stabilization Exercises in Adolescents With Idiopathic ScoliosisNot yet recruitingNCT07761260Not applicable
- Functional Limitations, Body Structure and Function Impairments, and Quality of Life in Adults After Surgical Treatment of Adolescent Idiopathic ScoliosisRecruitingNCT075595391 country
- Immune Response to PSF in Idiopathic vs Neuromuscular ScoliosisNot yet recruitingNCT077344671 country
- Wireless EMG-Based Monitoring of Paraspinal Muscle Activation in Adolescent Idiopathic ScoliosisNot yet recruitingNCT07738588Not applicable1 country
- Effect of a 16-Week Physiotherapeutic Corrective Exercise Program on Spinal Deformities in Adolescent Idiopathic ScoliosisEnrolling by invitationNCT07736456Not applicable1 country
- Feasibility, Acceptability, and Preliminary Effects of Virtual Reality for Pain, Anxiety and Recovery Enhancement of Children Post-scoliosis Surgical RepairNot yet recruitingNCT07737886Not applicable1 country
- Management of Early Onset Scoliosis by Active Apex Correction TechniqueRecruitingNCT07727408Not applicable1 country
- Evaluation of the Effect of Reiki on Pain After Lumbar SurgeryRecruitingNCT07722117Not applicable1 country
- Machine Learning-Guided LIV Selection for Adolescent Idiopathic ScoliosisNot yet recruitingNCT07723053Not applicable1 country
- PMCF (Post-Market Clinical Follow-up) Study on The Tether™ in UK (United Kingdom)RecruitingNCT058308251 country
- Schroth and Pilates for Adolescent Idiopathic ScoliosisRecruitingNCT07702812Not applicable1 country
- Smartphone App for Adolescents With Idiopathic ScoliosisNot yet recruitingNCT07686848Not applicable1 country
- Anterior Vertebral Body Tethering (AVBT) Using Zimmer Biomet Tether System or Dynesys System Components to Treat Pediatric ScoliosisEnrolling by invitationNCT03506334Not applicable1 country
- Psychometric Properties of the Turkish Version of the Staffordshire Adolescent Idiopathic Scoliosis QuestionnaireNot yet recruitingNCT076760191 country
- Apparent Diffusion Coefficient of the Intervertebral Disc in Children: Pilot StudyRecruitingNCT073312981 country
- Artificial Intelligence-Based Postural Feedback for ScoliosisNot yet recruitingNCT07669428Not applicable1 country
- Body Structure and Capacity Evaluation of Adults With ScoliosisRecruitingNCT055388711 country
- UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL StudyRecruitingNCT076346271 country
- Blood Transfusion Risk Factors and Cell Saver Impact in Pediatric Scoliosis SurgeryRecruitingNCT076615891 country
- Effects of Core Stabilization Exercises and Rotation Angular Breathing Exercises Among Idiopathic Scoliosis PatientsNot yet recruitingNCT07601893Not applicable1 country
- Mat-Pilates Exercises on Balance in Adolescents With ScoliosisNot yet recruitingNCT07638826Not applicable