An interventional study of Traditional schroth supervised exercise and OhShape virtual reality gameplay environment in Scoliosis and Scoliosis Idiopathic, sponsored by Cairo University. Not yet recruiting at 1 site in Egypt. Open to participants aged 10 Years to 19 Years. Per ClinicalTrials.gov, last updated 2026-08-31.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
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Among 13 studies in Scoliosis by Cairo University — 5 open to participants now, 5 under way, none of them phase 3. Scoliosis · Cairo University.
Among the 13 studies in Scoliosis by Cairo University, this one is one of 3 that started in 2026, is one of 9 with no phase, and was the 13th registered.
660 studies on the registry are indexed under Scoliosis; 186 are open to participants now.
Browse Scoliosis studies →5 of the 13 studies in Scoliosis by Cairo University are open now, in 1 country. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Ages 18–30
Cairo University
Ages 10–18
Cairo University · Sites in Egypt
Ages 13–18
Cairo University · Sites in Egypt
Ages 10–18
By country, each count listing its studies:
Of the 117 Scoliosis studies recruiting now, 23 (20%) set no upper age limit and 88 (75%) stop at 75 or younger; 98 take children under 18; 14 take healthy volunteers.
This study: 10 Years to 19 Years · all sexes · no healthy volunteers.
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13 studies; the count open now beside each. This study's row is marked.
First in 2018; this study’s year is marked. 3 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 54 is above the median of 45 across 386 interventional studies indexed under Scoliosis.
Median enrollment 54 across the 9 interventional studies, 47 across the 4 observational. Of the 6 that completed or were terminated, 0 (0%) have results posted.
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Cairo University is the lead sponsor of 4,951 studies on the registry; 1,463 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
2 of the studies in Scoliosis by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07413588Cairo UniversityImplementation of Specific Tailored Exercises Program Versus Exergaming Exercises on Cobb Angle in the Treatment of Adolescent Idiopathic Scoliosis. | 2026-12-10 |
| NCT07794020Cairo UniversityVirtual Reality-based Schroth Exercise Versus Traditional Schroth Exercise on Trunk Kinematics in Scoliosis | 2027-02-20 |
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Among the 13 studies in Scoliosis by Cairo University, from their registry updates:
Nothing recorded among them since 2026-09-25.
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The study will be conducted to compare three-dimensional trunk kinematics (rotation, tilt, and flexion/extension) and quality of life among adolescents with idiopathic scoliosis receiving traditional Schroth physiotherapeutic scoliosis-specific exercises, Schroth exercises combined with immersive virtual reality using Meta Quest 2 (OhShape), and Schroth exercises combined with low-cost mobile virtual reality using Google Cardboard with a gaze-controlled game.
Physiotherapeutic scoliosis-specific exercises (PSSE), particularly the Schroth method, are widely recommended as a first-line conservative treatment for adolescent idiopathic scoliosis and have demonstrated effectiveness in reducing curve progression, improving posture, and enhancing quality of life. However, the long-term success of Schroth rehabilitation is highly dependent on patient adherence and the accurate execution of complex three-dimensional corrective postures, which remain challenging for adolescents to maintain outside supervised clinical settings.
Poor adherence to traditional Schroth programs has been reported, with rates ranging between 30% and 50%, limiting the real-world effectiveness of conservative scoliosis management. Adolescents frequently report low motivation, boredom, and difficulty understanding or maintaining corrective postures without continuous feedback, which compromises motor learning and postural control.
Digital rehabilitation technologies, particularly virtual reality (VR), have emerged as promising tools to enhance engagement, motivation, and motor learning in rehabilitation programs. VR-based exercise has demonstrated positive effects on adherence, movement accuracy, and postural awareness in neurological and musculoskeletal rehabilitation. Immersive VR platforms provide real-time visual and auditory feedback and promote task-oriented training in an engaging gaming environment, which is particularly suitable for adolescent populations.
To date, no randomized controlled trial has directly compared immersive high-end VR platforms with low-cost mobile VR solutions for the delivery of scoliosis-specific exercises, nor has any study quantified real-time trunk kinematics during VR-guided Schroth rehabilitation using Wearable inertial measurement units (IMUs) technology. Evaluating these interventions may provide clinicians with valuable insight into cost-effective, scalable, and engaging rehabilitation strategies for adolescents with idiopathic scoliosis, particularly in resource-limited healthcare settings
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Exclusion Criteria:
participants will perform traditional supervised Schroth physiotherapeutic scoliosis-specific exercises for 45 minutes.
Other: Traditional schroth supervised exercise
Participants will perform identical Schroth physiotherapeutic scoliosis-specific exercises in addition of integration into the OhShape virtual reality gameplay environment for 45 minutes
Other: Traditional schroth supervised exercise · Other: OhShape virtual reality gameplay environment
Participants will perform identical Schroth physiotherapeutic scoliosis-specific exercises in addition of a low-cost mobile virtual reality intervention delivered via Google Cardboard for 45 minutes.
Other: Traditional schroth supervised exercise · Other: Google Cardboard Mobile Virtual reality Zombie Shooter
participants will perform traditional supervised Schroth physiotherapeutic scoliosis-specific exercises. The intervention consists of two supervised sessions per week, 45 minutes each, for 12 weeks
OhShape is a posture-matching rhythm-based VR game that requires users to perform precise trunk and body movements in response to visual and auditory cues, thereby promoting postural awareness, motor coordination, and movement accuracy. The Meta Quest 2 headset provides a fully immersive virtual reality experience with six degrees of freedom (6DOF) head and body tracking, allowing real-time spatial interaction and posture-based feedback during exercise execution.
It is a low-cost mobile virtual reality (VR) intervention delivered via Google Cardboard. A custom Unity-based zombie-shooting VR game will be used, in which participants are required to maintain the corrected Schroth posture while engaging in a gaze-controlled shooting task, using head and trunk alignment to aim and interact with virtual targets. Mobile VR platforms such as Google Cardboard provide three degrees of freedom (3DOF) tracking and represent an accessible, low-cost alternative to high-end immersive VR systems.
Trunk kinematics: Trunk rotation angle (Yaw)
Derived from gyroscope data(gyroZ) using wearable inertial measurement units (IMUs) to measure dynamic rotation toward midline during exercise execution.
Time frame: 16 weeks
Trunk kinematics: trunk tilt angle (roll/ pitch)
derived from accelerometer data (accX, accY) using IMUs to assess frontal plane trunk asymmetry correction during exercise execution.
Time frame: 16 weeks
Trunk Kinematics: Trunk flexion/ extension angle
Derived from accelerometer data relative to gravity using wearable inertial measurement unit (IMUs) to monitor sagittal plane alignment during exercise execution.
Time frame: 16 weeks
Corrected posture holding time
The cumulative duration (seconds ) and percentage of session time during which participants maintain the predefined curve specific corrected trunk posture within acceptable angular deviation threshold, quantified via real-time 50 Hz.
Time frame: 16 weeks
Health related quality of life (SRS-22r)
Assessed using the scoliosis research society-22r questionnaire mean domain scores evaluating pain, self image, function, mental health and satisfaction. The score is graded from 1 to 5; 1 means the worst and 5 means the best quality of life.
Time frame: 16 weeks
pediatric health utility (EQ-5D-Y and EQ-VAS)
Assessed using the EuroQol 5 dimention youth version utility scores and the self rated EuroQol visual analogue scale (0-100) to measure overall health status. 0 means the worst and 100 means the best health.
Time frame: 16 weeks
Trial retention rate
To assess feasibility, calculated as the percentage of randomized participants who successfully complete post treatment assessment and follow-up periods.
Time frame: 16 weeks
intervention adherence rate
Quantified using clinic attendance logs calculated as (attended sessions / scheduled sessions)\*100 to categorize participants into high, moderate or low adherence.
Time frame: 16 weeks
Safety and incidence of adverse events
Percentage of participants experiencing treatment related adverse events such as muscle strain or safe withdrawals from the study.
Time frame: 16 weeks
Start is estimated for Sep 2026; primary completion for Feb 2027, 5 months later.
Of 223 non-industry interventional studies with no phase under Scoliosis, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 58. This study's planned 5 months is below that.
Counting every sponsor, half of 233 studies reached it within 22 months; a quarter within 8 and three quarters within 60.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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