An observational study in Adolescent Idiopathic Scoliosis (AIS), sponsored by Gaziler Physical Medicine and Rehabilitation Education and Research Hospital. Not yet recruiting. Open to participants aged 10 Years to 18 Years. Per ClinicalTrials.gov, last updated 2026-10-28.
Sponsored by Gaziler Physical Medicine and Rehabilitation Education and Research Hospital · Observational
This single-center, observational, cross-sectional study aims to investigate the association between fecal calprotectin levels and clinical characteristics in adolescents with idiopathic scoliosis. Clinical, radiological, anthropometric, nutritional, and laboratory parameters will be evaluated to explore potential relationships with curve severity.
660 studies on the registry are indexed under Scoliosis; 186 are open to participants now.
This study's planned enrollment of 83 is close to the median of 84 across 256 observational studies indexed under Scoliosis.
Browse Scoliosis studies →Gaziler Physical Medicine and Rehabilitation Education and Research Hospital is the lead sponsor of 85 studies on the registry; 14 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adolescents aged 10-18 years diagnosed with idiopathic scoliosis who attend a specialized scoliosis outpatient clinic and meet the study eligibility criteria.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Adolescents aged 10-18 years with a confirmed diagnosis of idiopathic scoliosis (Cobb angle ≥10°).
No clinical evidence of acute or chronic infection or significant systemic inflammation.
No recent infection within the preceding three months.
No history of gastrointestinal disease or recent antibiotic/probiotic use.
No previous scoliosis surgery.
Voluntary participation with appropriate .
Exclusion Criteria:
Congenital, neuromuscular, or syndromic scoliosis.
Inflammatory bowel disease, celiac disease, or other chronic inflammatory disorders, rheumatological disease, or .
Family history of inflammatory bowel disease or celiac disease.
Recent gastrointestinal symptoms, including diarrhea, gastrointestinal bleeding, unexplained abdominal pain, or weight loss.
Infection within the preceding three months.
Use of , NSAIDs, or medications within the preceding three months.
Pregnancy.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Autoimmune disease
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Association Between Fecal Calprotectin Levels and Cobb Angle
Fecal calprotectin levels (µg/g) will be measured and their association with radiographic Cobb angle (degrees) will be evaluated.
Time frame: At enrollment (single assessment)
Scoliosis Progression Risk Index
Association of fecal calprotectin levels with the Lonstein-Carlson progression risk index.
Time frame: At enrollment (single assessment)
Body Composition Parameters
Association of fecal calprotectin levels with body mass index, fat mass, fat-free mass, and body fat percentage.
Time frame: At enrollment (single assessment)
Dietary Habits
Association of fecal calprotectin levels with dietary habits assessed using a standardized questionnaire.
Time frame: At enrollment (single assessment)
No study locations are listed for this record.
Plan to share: No — Individual participant data will not be publicly shared due to participant privacy and confidentiality considerations.
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Gaziler Physical Medicine and Rehabilitation Education and Research Hospital