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RecruitingNCT06314594Updated Feb 23, 2026

Personalized Prevention and Treatment Strategies for Adolescent Idiopathic Scoliosis Via a Comprehensive Health Management Platform

An interventional study of Conventional treatment and intervention treatment in Adolescent Idiopathic Scoliosis (AIS), sponsored by Hangzhou Medical College. Recruiting at 1 site in China. Open to participants aged 3 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-23.

Sponsored by Hangzhou Medical College · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Aug 2025; still recruiting 1 year 2 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
76
Allocation
Randomized
Ages
3 Years to 18 Years
Sex
All
01

Study summary

Spinal cord injury (SCI), leads to functional deficits and complications like neurogenic bladder and deep vein thrombosis, imposing a global annual financial burden. This trial aims to compares Jiaji electroacupuncture (JEA) and scalp electroacupuncture (SEA) in SCI rehabilitation. This randomized controlled trial (RCT) compared JEA and SEA in SCI rehabilitation.

Read the detailed description

This study employed a randomized controlled clinical trial method to compare the effects of JEA and SEA interventions on the clinical outcomes of patients with traumatic spinal cord injury (TSCI). The findings revealed that, compared to SEA, JEA intervention demonstrated superior performance in improving patients' ASIA grading, motor function scores, light touch sensation scores, pinprick sensation scores, and modified Barthel index. This indicates that JEA has a significant advantage in promoting the enhancement of ASIA grading, recovery of motor and sensory function scores, and improvement in daily living activities among TSCI patients. The conclusions of this study further substantiate the positive role of JEA in ameliorating motor function, sensory function scores, and daily living conditions in patients with spinal cord injury.

02

Conditions studied

  • Adolescent Idiopathic Scoliosis (AIS)

Keywords

  • spinal cord injury; electroacupuncture; Jiaji acupoint; scalp acupuncture; clinical efficacy
03

In context

Spinal Cord Injuries

1,948 studies on the registry are indexed under Spinal Cord Injuries; 505 are open to participants now.

This study's planned enrollment of 76 is above the median of 24 across 1,566 interventional studies indexed under Spinal Cord Injuries.

Browse Spinal Cord Injuries studies →

Lead sponsor

Hangzhou Medical College is the lead sponsor of 3 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
3 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. The diagnosis of moderate and mild AIS, with a Cobb angle measuring less than 45°;
  2. The age range of 12 to 16 years old;
  3. Participants are required to have no history of mental illness, possess normal communication skills, and be proficient in reading and writing;
  4. Signed informed consent by the patient or their family.

Exclusion criteria

Exclusion Criteria:

Patients who fulfill any of the following conditions will be excluded a clear history of inducement, such as diseases caused by trauma, surgery, cognitive impairment, severe dysfunction of heart, liver, kidney and other organs, and malignant tumors, immune diseases and other malignant diseases.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Care provider, Outcomes assessor)
Enrollment
76 participants (estimated)

Study arms

  • No intervention
    control

    Conventional treatment

  • Experimental
    intervention

    Using paradigms based on transfer learning and semi-supervised learning, using multiple learning methods, transformer image classification algorithms and other mathematical methods, an early warning model and stepped treatment model for adolescent scoliosis were developed and verified, and a cost-effectiveness analysis was conducted at the same time.

    Procedure: Conventional treatment · Behavioral: intervention treatment

Interventions

  • ProcedureConventional treatment

    Patients will randomly assigned to routine treatment group (control group) and individualized treatment model group (intervention group). All patients will observed and intervened for 4 months. Patients in the control treatment group will follow the treatment plan in the 2016SOSORT guidelines

  • Behavioralintervention treatment

    Patients will be input into the health management platform. The optimal treatment scheme will be then determined through data calculation and sent to individuals (or their families) or schools for implementation under the guidance of the platform. It is important to note that the specific treatment plan varied from person to person. Patients were observed and intervened for a period of 4 months. 1. Massage therapy 2. Posture guidance 3. Schroeder\'s gymnastics therapy 4. Bioelectric stimulation therapy

06

What researchers measure

Primary outcomes

  1. Number of Cobb angles

    X-rays were used to check the number of Cobb angles before and 4 months after the intervention to observe the improvement of scoliosis

    Time frame: 4 months before the intervention and 4 months after the intervention

  2. Accuracy of new screening modalities

    The new screening method "general examination + forward flexion test + scoliosis measuring instrument" was used for examination, and the data results before and 4 months after intervention were compared with the X-ray examination results to verify its accuracy.

    Time frame: 4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention

  3. Hamilton Depression Volume

    Depression status was rated using the Hamilton Depression Rating Scale

    Time frame: 4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention

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Study locations

1 of 1 sites recruiting
  • the Affiliated Zhejiang Provincial People's Hospital to Hangzhou Medical College.
    Hangzhou, Zhejiang 311000, China
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06314594
Lead sponsor
Hangzhou Medical College
Responsible party
Sponsor
First posted
Mar 18, 2024
Start date
Aug 1, 2025
Primary completion
Dec 1, 2025
Completion
Dec 1, 2026 (estimated)
Last update
Feb 23, 2026

Study contacts

Xinyun Dr LI, Doctor
Contact
lxyjasmine2010@163.com
8618069783240
Xinyun Dr Li, doctor
principal investigator · hangzhou medical colleage

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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