Sarcoma, Ewing clinical trials
The registry lists 287 studies for Sarcoma, Ewing across more than 10 countries. 66 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 136
- Recruiting
- 54
- Active, not recruiting
- 31
- Terminated
- 20
- Status unknown
- 15
- Withdrawn
- 15
Phase
- Phase 2
- 137
- Phase 1
- 112
- Phase 3
- 12
- Early Phase 1
- 3
- Phase 4
- 1
Where
- United States
- 198
- Italy
- 29
- France
- 26
- Canada
- 26
- Australia
- 19
- United Kingdom
- 19
Who runs them
National Cancer Institute (NCI) (44) · Children's Oncology Group (20) · St. Jude Children's Research Hospital (14) · Istituto Ortopedico Rizzoli (9) · Memorial Sloan Kettering Cancer Center (6) · Peking University People's Hospital (6) · Dana-Farber Cancer Institute (6) · Gradalis, Inc. (5)
Studies
Recruiting first, then most recently updated. Showing 50 of 287 — search for more.
- Metastatic Ewing's Trial Testing Schedule Enhancement to Improve OutcomesRecruitingNCT07194044Phase 11 country
- Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)RecruitingNCT07297979Phase 12 countries
- A Study of DXC008 in Patients With Prostate Cancer and Other Solid TumorsRecruitingNCT06926283Phase 11 country
- A Phase 1/2 Study of CBX-12 in Children, Adolescents, or Young Adults With Solid Tumors That Have Come Back After Treatment or Are Difficult to TreatNot yet recruitingNCT07830667Phase 1/2
- Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)RecruitingNCT06395103Phase 1/223 countries
- EWSR1 Immunotherapy in Ewing Sarcoma and DSRCTNot yet recruitingNCT07695311Phase 11 country
- Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including SarcomasRecruitingNCT03715933Phase 16 countries
- Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid TumorsRecruitingNCT06541262Phase 1/22 countries
- Cabozantinib With Ifosfamide in Relapsed/Refractory SarcomasRecruitingNCT06156410Phase 11 country
- Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and SarcomasRecruitingNCT06465199Phase 1/21 country
- Lurbinectedin in FET-Fused TumorsRecruitingNCT05918640Phase 1/21 country
- Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting SarcomasNot yet recruitingNCT03356782Phase 1/21 country
- Combination Immunotherapy Targeting SarcomasNot yet recruitingNCT04433221Phase 1/21 country
- Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsRecruitingNCT04851119Phase 1/21 country
- RAPID: Phase 2 Platform Trial Of Promising Drugs For AYA Patients With R/R Ewing Sarcoma & DSRCTNot yet recruitingNCT07781891Phase 21 country
- To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)RecruitingNCT05968768Phase 21 country
- Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's LymphomaRecruitingNCT07514819Not applicable1 country
- Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)RecruitingNCT07172958Phase 11 country
- Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory SarcomasRecruitingNCT05210374Phase 11 country
- Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid TumorsRecruitingNCT07628634Early Phase 11 country
- Prospective Evaluation of Dynamic Serum ProGRP for Treatment Response Monitoring in Ewing SarcomaRecruitingNCT077257831 country
- Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone SarcomaRecruitingNCT06796543Not applicable1 country
- Eflornithine (DFMO) for Ewing Sarcoma and OsteosarcomaRecruitingNCT07321912Phase 21 country
- Identification of Circulating Biomarkers Associated With Extracellular Vesicles in SarcomasRecruitingNCT076854051 country
- Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid TumorsRecruitingNCT06625190Phase 1/21 country
- XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue SarcomaRecruitingNCT06571734Phase 21 country
- Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR TrialRecruitingNCT07188532Not applicable1 country
- Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing SarcomaNot yet recruitingNCT076204311 country
- A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid MalignanciesRecruitingNCT07197554Phase 11 country
- B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)RecruitingNCT04897321Phase 11 country
- Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing SarcomaRecruitingNCT04901702Phase 1/22 countries
- Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)RecruitingNCT06094101Phase 1/21 country
- Assessment of Healing and Function After Reconstruction Surgery for Bone SarcomasRecruitingNCT034424651 country
- Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS MalignanciesRecruitingNCT04308330Phase 11 country
- my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young AdultsNot yet recruitingNCT07516353Not applicable1 country
- Single Arm Romiplostim to Prevent CITRecruitingNCT07048249Early Phase 11 country
- Reduced Intensity Haploidentical BMT for High Risk Solid TumorsRecruitingNCT01804634Phase 21 country
- Liposomal Irinotecan, Vincristine, Temozolomide, and Anlotinib for R/R Pediatric Solid TumorsNot yet recruitingNCT07444918Phase 2
- Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory SarcomasRecruitingNCT06709495Phase 1/21 country
- Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone SarcomasRecruitingNCT04055220Not applicable1 country
- Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory SarcomasRecruitingNCT07222735Phase 11 country
- A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative PlanningRecruitingNCT06387485Not applicable1 country
- Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing SarcomaRecruitingNCT05734066Phase 1/22 countries
- Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage SurgeryRecruitingNCT057796701 country
- HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced SarcomaRecruitingNCT04995003Phase 11 country
- Observational Study on Skeletal Ewing's SarcomaRecruitingNCT048458931 country
- Molecular Analysis Of Solid TumorsRecruitingNCT010502961 country
- Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid TumorsRecruitingNCT02508038Phase 11 country
- Combination of Pembrolizumab and Cabozantinib in Patients With Advanced SarcomasRecruitingNCT05182164Phase 21 country
- Fertility Preservation in Children With Solid Tumors: Detection of Residual Disease by a Sensitive MethodRecruitingNCT071418621 country