Drug

Irinotecan clinical trials

Also written Camptosar, CPT-11, Campto and U-101440E.

Includes 72 studies of Irinotecan sucrosofate, 2 studies of Liposomal SN-38 and 1 study of Pegylated Liposomal Irinotecan.

studies test it: 868
open now: 130
in phase 3: 81
first study started: 1995

Counted the way a researcher would: Irinotecan with its salts, dosage forms, brands and biosimilars. Looking for a trial to join? Including related medicines shows more you could take part in.

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Keep track of what changes. Save the Irinotecan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.

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How studies write it

Studies that test it under each name

Name

Irinotecan: 396
irinotecan hydrochloride: 251
Camptothecin-11: 35
Liposomal Irinotecan: 24
Camptothecin 11: 23

Brand

Camptosar: 145
Campto: 81
Onivyde: 7

Development codes

CPT-11: 131
U-101440E: 55
PEP02: 3
NKTR-102: 2
NSC-616348: 2

Written with another drug

Irinotecan, Capecitabine: 4
NK012: 3
mFOLFIRINOX Treatment Regimen: 3
Irinotecan and cisplatin: 2
irinotecan + cisplatin: 2
HM30181AK tablet + Irinotecan tablets: 2
S-1, Irinotecan, Bevacizumab: 2
S-1, irinotecan, oxaliplatin: 2

Studies by the year they started

862 studies that test it; most in 2003 (46); 1 more planned to start later

Studies that test Irinotecan, by start year
Year	Studies
1995	1
1996	3
1997	10
1998	22
1999	26
2000	25
2001	31
2002	33
2003	46
2004	39
2005	33
2006	44
2007	32
2008	37
2009	35
2010	22
2011	24
2012	23
2013	25
2014	28
2015	22
2016	23
2017	25
2018	30
2019	31
2020	29
2021	27
2022	26
2023	21
2024	44
2025	26
2026	19

By phase

A phase 1/2 study counts in both.

Early Phase 1: 4
Phase 1: 303
Phase 2: 571
Phase 3: 81
Phase 4: 8
No phase: 12

What it is tested for

Each study’s main condition, where its own words name it.

Colorectal Neoplasms: 198
Neoplasms: 66
Small Cell Lung Carcinoma: 49
Stomach Neoplasms: 47
Adenocarcinoma: 45
Pancreatic Neoplasms: 43
Glioblastoma: 31
Rectal Neoplasms: 19
Breast Neoplasms: 19
Carcinoma: 19
Carcinoma, Non-Small-Cell Lung: 18
Glioma: 17

Who runs them

Industry 129 · Other 739

National Cancer Institute (NCI) (47) · Alliance for Clinical Trials in Oncology (29) · Memorial Sloan Kettering Cancer Center (28) · M.D. Anderson Cancer Center (16) · Children's Oncology Group (15) · Roswell Park Cancer Institute (14) · Pfizer (13) · Fudan University (13)

Often tested with

Tested in the same studies.

Fluorouracil (151) · Oxaliplatin (135) · Leucovorin (92) · Bevacizumab (80) · Cisplatin (72) · Temozolomide (67) · Capecitabine (65) · Cetuximab (61)

Studies

Open first, then newest update. How each study uses Irinotecan is read from its arms, and is right about nine times in ten.

Testing it · 868

See all 868 studies that test Irinotecan →

Given in every arm · 318 — Irinotecan is usual care beside what is tested

Showing 20 of 318.

As the comparator · 59 — what is tested is compared with Irinotecan

Showing 20 of 59.

Codes

What other systems call Irinotecan · ClinicalTrials.gg INT006650

MeSH (NLM) D000077146IrinotecanConfirmed ClinicalTrials.gov, NLM, Wikidata
UNII (FDA) 7673326042IRINOTECANConfirmed FDA, NLM, Wikidata
RxNorm 51499Confirmed FDA, Wikidata
Wikidata Q412197irinotecanConfirmed FDA, NLM, Wikidata
NCI Thesaurus C62040IrinotecanOne source FDA
DrugBank DB00762One source Wikidata

System	Code	Name there	Checked by
MeSH (NLM)	D000077146	Irinotecan	Confirmed ClinicalTrials.gov, NLM, Wikidata
UNII (FDA)	7673326042	IRINOTECAN	Confirmed FDA, NLM, Wikidata
RxNorm	51499	—	Confirmed FDA, Wikidata
Wikidata	Q412197	irinotecan	Confirmed FDA, NLM, Wikidata
NCI Thesaurus	C62040	Irinotecan	One source FDA
DrugBank	DB00762	—	One source Wikidata

Also registered as 7-ethyl-10-hydroxycamptothecin (UNII 0H43101T0J) and irinotecan hydrochloride (UNII 042LAQ1IIS · RxNorm 153329).

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.