Osteosarcoma clinical trials
The registry lists 436 studies for Osteosarcoma across more than 10 countries. 115 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 180
- Recruiting
- 93
- Status unknown
- 46
- Active, not recruiting
- 40
- Terminated
- 34
- Not yet recruiting
- 19
Phase
- Phase 2
- 199
- Phase 1
- 127
- Phase 3
- 23
- Early Phase 1
- 10
- Phase 4
- 3
Where
- United States
- 241
- China
- 55
- Canada
- 34
- France
- 34
- Italy
- 30
- Puerto Rico
- 24
Who runs them
National Cancer Institute (NCI) (52) · Children's Oncology Group (24) · Peking University People's Hospital (22) · St. Jude Children's Research Hospital (19) · Memorial Sloan Kettering Cancer Center (11) · M.D. Anderson Cancer Center (11) · Istituto Ortopedico Rizzoli (8) · Emory University (7)
Studies
Recruiting first, then most recently updated. Showing 50 of 436 — search for more.
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed OsteosarcomaRecruitingNCT07560826Phase 21 country
- Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell TumorRecruitingNCT04616560Phase 21 country
- Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer: A Randomized Controlled TrialNot yet recruitingNCT07820033Phase 21 country
- Clinical Orthopaedic Data Bank (Acute and Chronic)RecruitingNCT004110601 country
- A Study to Assess Safety and Efficacy of SOT106 in Patients With LRRC15-positive Advanced Unresectable or Metastatic Osteosarcoma or Soft Tissue SarcomaNot yet recruitingNCT07801222Phase 1/21 country
- Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid TumorsRecruitingNCT06541262Phase 1/22 countries
- Cabozantinib With Ifosfamide in Relapsed/Refractory SarcomasRecruitingNCT06156410Phase 11 country
- Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and SarcomasRecruitingNCT06465199Phase 1/21 country
- Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and OsteosarcomaRecruitingNCT07725380Phase 1/21 country
- Observational Study in Localized OsteosarcomaRecruitingNCT048900671 country
- Losartan + Sunitinib in Treatment of OsteosarcomaRecruitingNCT03900793Phase 11 country
- Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe TrialRecruitingNCT07227571Phase 11 country
- Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk OsteosarcomaRecruitingNCT07428993Phase 21 country
- Evaluation of the Safety and Efficacy of Mifamurtide Versus Standard Treatment With Sorafenib in Patients With High-risk OsteosarcomaRecruitingNCT07787429Phase 21 country
- Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With OsteosarcomaRecruitingNCT05235165Phase 36 countries
- Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsRecruitingNCT04851119Phase 1/21 country
- Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's LymphomaRecruitingNCT07514819Not applicable1 country
- 68Ga-B7-H3 Nanobody ImmunoPET in OsteosarcomaRecruitingNCT07774533Early Phase 11 country
- SPEARHEAD-3 Pediatric StudyRecruitingNCT05642455Phase 1/21 country
- Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory SarcomasRecruitingNCT05210374Phase 11 country
- Musculoskeletal Cancers Remote Monitoring and CareRecruitingNCT07129226Not applicable1 country
- NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)RecruitingNCT06239272Phase 1/21 country
- Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid TumorsRecruitingNCT07628634Early Phase 11 country
- AOH1996 for the Treatment of Refractory Solid TumorsRecruitingNCT05227326Phase 11 country
- Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway AlterationRecruitingNCT04040205Phase 21 country
- NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or NeuroblastomaRecruitingNCT07211737Phase 11 country
- Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary MetastasesRecruitingNCT03093909Phase 11 country
- Eflornithine (DFMO) for Ewing Sarcoma and OsteosarcomaRecruitingNCT07321912Phase 21 country
- Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid TumorsRecruitingNCT06625190Phase 1/21 country
- XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue SarcomaRecruitingNCT06571734Phase 21 country
- Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer PatientsRecruitingNCT075028851 country
- Tumor Neoantigen Vaccine SarVac Combined With Tumor Specific Lymphocyte Reinfusion in the Treatment of Advanced SarcomaRecruitingNCT07648069Phase 11 country
- Safety and Feasibility of Intraoperative Visualization With Cytalux in ChildrenRecruitingNCT06235125Phase 11 country
- Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).RecruitingNCT06607692Phase 1/21 country
- Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed OsteosarcomaRecruitingNCT06492954Phase 11 country
- Tegavivint With Gemcitabine in Patients With Relapsed or Refractory OsteosarcomaRecruitingNCT07144254Phase 11 country
- Cryoablation Plus Camrelizumab for Advanced Soft Tissue SarcomaRecruitingNCT07602049Phase 21 country
- B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)RecruitingNCT04897321Phase 11 country
- Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing SarcomaRecruitingNCT04901702Phase 1/22 countries
- Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer TreatmentRecruitingNCT017901524 countries
- START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of CancerRecruitingNCT05492682Phase 12 countries
- Expanded Access Use of L-MTP-PE for the Treatment of OsteosarcomaAvailableNCT045712291 country
- An Organoid-based Functional Precision Medicine Trial in OsteosarcomaRecruitingNCT060646821 country
- Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid TumorsRecruitingNCT06500819Phase 11 country
- Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue SarcomasRecruitingNCT07052383Phase 11 country
- Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)RecruitingNCT07357519Phase 1/21 country
- Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With CancerRecruitingNCT05297734Not applicable1 country
- Assessment of Healing and Function After Reconstruction Surgery for Bone SarcomasRecruitingNCT034424651 country
- Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS StudyRecruitingNCT05019703Phase 21 country
- Agnostic Therapy in Rare Solid TumorsRecruitingNCT06638931Phase 21 country