Sarcoma, Ewing: all 290 studies
Page 1 of 3. Open to participants first (67), then studies with results posted, then the rest; newest registration first within each.
- A Phase 1/2 Study of CBX-12 in Children, Adolescents, or Young Adults With Solid Tumors That Have Come Back After Treatment or Are Difficult to TreatNot yet recruitingNCT07830667Phase 1/2
- RAPID: Phase 2 Platform Trial Of Promising Drugs For AYA Patients With R/R Ewing Sarcoma & DSRCTNot yet recruitingNCT07781891Phase 2
- Prospective Evaluation of Dynamic Serum ProGRP for Treatment Response Monitoring in Ewing SarcomaRecruitingNCT07725783
- EWSR1 Immunotherapy in Ewing Sarcoma and DSRCTNot yet recruitingNCT07695311Phase 1
- Identification of Circulating Biomarkers Associated With Extracellular Vesicles in SarcomasRecruitingNCT07685405
- Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid TumorsRecruitingNCT07628634Early Phase 1
- Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing SarcomaNot yet recruitingNCT07620431
- my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young AdultsNot yet recruitingNCT07516353Not applicable
- Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's LymphomaRecruitingNCT07514819Not applicable
- Liposomal Irinotecan, Vincristine, Temozolomide, and Anlotinib for R/R Pediatric Solid TumorsNot yet recruitingNCT07444918Phase 2
- Eflornithine (DFMO) for Ewing Sarcoma and OsteosarcomaRecruitingNCT07321912Phase 2
- Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)RecruitingNCT07297979Phase 1
- Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory SarcomasRecruitingNCT07222735Phase 1
- A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid MalignanciesRecruitingNCT07197554Phase 1
- Metastatic Ewing's Trial Testing Schedule Enhancement to Improve OutcomesRecruitingNCT07194044Phase 1
- Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR TrialRecruitingNCT07188532Not applicable
- Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)RecruitingNCT07172958Phase 1
- Fertility Preservation in Children With Solid Tumors: Detection of Residual Disease by a Sensitive MethodRecruitingNCT07141862
- A Randomized Controlled Study Comparing the Safety and Efficacy of Irinotecan Hydrochloride Liposome Injection Combined With Temozolomide and Vincristine (NALIRI-VT) Versus Irinotecan Combined With Temozolomide and Vincristine (VIT) in Patients With Advanced Ewing's SarcomaNot yet recruitingNCT07092306Phase 2
- Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced SarcomasRecruitingNCT07066982Phase 1/2
- Single Arm Romiplostim to Prevent CITRecruitingNCT07048249Early Phase 1
- Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone TumorsRecruitingNCT06935864
- A Study of DXC008 in Patients With Prostate Cancer and Other Solid TumorsRecruitingNCT06926283Phase 1
- International Phase I Trial of Dinutuximab Beta With VDC/IE in GD2-Positive Ewing SarkomaNot yet recruitingNCT06839703Phase 1
- Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing SarcomaRecruitingNCT06827717Phase 2
- Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone SarcomaRecruitingNCT06796543Not applicable
- Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory SarcomasRecruitingNCT06709495Phase 1/2
- A Prospective, Randomized, Controlled Clinical Study on the Prevention of Chemotherapy Related Myelosuppression in Patients with Ewing's Sarcoma Using TrilaciclibRecruitingNCT06699472Phase 2
- Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid TumorsRecruitingNCT06625190Phase 1/2
- XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue SarcomaRecruitingNCT06571734Phase 2
- A Study of KC1036 in Adolescents With Advanced Ewing SarcomaRecruitingNCT06564272Phase 2
- Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid TumorsRecruitingNCT06541262Phase 1/2
- Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and SarcomasRecruitingNCT06465199Phase 1/2
- Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)RecruitingNCT06395103Phase 1/2
- A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative PlanningRecruitingNCT06387485Not applicable
- Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing SarcomaRecruitingNCT06340204Phase 1
- Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing SarcomaRecruitingNCT06243588
- Cabozantinib With Ifosfamide in Relapsed/Refractory SarcomasRecruitingNCT06156410Phase 1
- Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)RecruitingNCT06094101Phase 1/2
- Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton TherapyRecruitingNCT06029218Not applicable
- To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)RecruitingNCT05968768Phase 2
- Lurbinectedin in FET-Fused TumorsRecruitingNCT05918640Phase 1/2
- Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage SurgeryRecruitingNCT05779670
- Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing SarcomaRecruitingNCT05734066Phase 1/2
- Use of GnRHa During Chemotherapy for Fertility ProtectionRecruitingNCT05328258Phase 3
- A Rollover Protocol to Allow for Continued Access to the LSD1 Inhibitor Seclidemstat (SP-2577)Enrolling by invitationNCT05266196Phase 1/2
- Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory SarcomasRecruitingNCT05210374Phase 1
- Combination of Pembrolizumab and Cabozantinib in Patients With Advanced SarcomasRecruitingNCT05182164Phase 2
- A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid TumorsRecruitingNCT05135975Phase 2
- Early Ageing During Therapy in AYA Cancer PatientsRecruitingNCT05062707
- HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced SarcomaRecruitingNCT04995003Phase 1
- Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing SarcomaRecruitingNCT04901702Phase 1/2
- B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)RecruitingNCT04897321Phase 1
- Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsRecruitingNCT04851119Phase 1/2
- Observational Study on Skeletal Ewing's SarcomaRecruitingNCT04845893
- Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of RelapseRecruitingNCT04758000Phase 2
- Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone SarcomaRecruitingNCT04735289
- Combination Immunotherapy Targeting SarcomasNot yet recruitingNCT04433221Phase 1/2
- Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS MalignanciesRecruitingNCT04308330Phase 1
- Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone SarcomasRecruitingNCT04055220Not applicable
- Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including SarcomasRecruitingNCT03715933Phase 1
- Assessment of Healing and Function After Reconstruction Surgery for Bone SarcomasRecruitingNCT03442465
- Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting SarcomasNot yet recruitingNCT03356782Phase 1/2
- Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid TumorsRecruitingNCT02508038Phase 1
- Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid TumorsRecruitingNCT02013336Phase 1
- Reduced Intensity Haploidentical BMT for High Risk Solid TumorsRecruitingNCT01804634Phase 2
- Molecular Analysis Of Solid TumorsRecruitingNCT01050296
- CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's SarcomaActive, not recruitingNCT05440786Phase 2Results posted
- A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid TumorsCompletedNCT05093322Phase 1/2Results posted
- Elimusertib for the Treatment of Relapsed or Refractory Solid TumorsActive, not recruitingNCT05071209Phase 1/2Results posted
- A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant CancerTerminatedNCT04730349Phase 1/2Results posted
- Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04320888Phase 2Results posted
- Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04284774Phase 2Results posted
- A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaCompletedNCT04238819Phase 1/2Results posted
- Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT04195555Phase 2Results posted
- Palbociclib + Ganitumab In Ewing SarcomaTerminatedNCT04129151Phase 2Results posted
- Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid TumorsCompletedNCT03709680Phase 2Results posted
- Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03698994Phase 2Results posted
- Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03526250Phase 2Results posted
- A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and TemozolomideTerminatedNCT03495921Phase 3Results posted
- Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric PatientsTerminatedNCT03458728Phase 1/2Results posted
- Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)CompletedNCT03441360Phase 2Results posted
- Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Children With Refractory or Recurrent Solid TumorsCompletedNCT03245450Phase 1/2Results posted
- Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03233204Phase 2Results posted
- Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03220035Phase 2Results posted
- Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03213678Phase 2Results posted
- Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03213665Phase 2Results posted
- Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain CancersCompletedNCT03190174Phase 1/2Results posted
- Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)Active, not recruitingNCT03155620Phase 2Results posted
- Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory SarcomaCompletedNCT02945800Phase 2Results posted
- Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare TumorsActive, not recruitingNCT02867592Phase 2Results posted
- TK216 in Patients With Relapsed or Refractory Ewing SarcomaTerminatedNCT02657005Phase 1/2Results posted
- Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)TerminatedNCT02624388Phase 2Results posted
- Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms TumorsTerminatedNCT02581384Phase 1/2Results posted
- Eurosarc Trial of Linsitinib in Advanced Ewing SarcomaCompletedNCT02546544Phase 2Results posted
- A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's SarcomaCompletedNCT02511132Phase 2Results posted
- Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing SarcomaActive, not recruitingNCT02306161Phase 3Results posted
- Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or SarcomasCompletedNCT02304458Phase 1/2Results posted
- Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing SarcomaActive, not recruitingNCT02243605Phase 2Results posted
- Molecular-Guided Therapy for Childhood CancerCompletedNCT02162732Not applicableResults posted