Polymyositis clinical trials
The registry lists 70 studies for Polymyositis across more than 10 countries. 20 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 40
- Recruiting
- 17
- Terminated
- 4
- Active, not recruiting
- 3
- Status unknown
- 3
- Enrolling by invitation
- 2
Phase
- Phase 2
- 26
- Phase 3
- 14
- Phase 1
- 12
- Early Phase 1
- 1
Where
- United States
- 41
- Czechia
- 12
- Sweden
- 11
- France
- 11
- Japan
- 11
- United Kingdom
- 9
Who runs them
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (5) · National Institute of Environmental Health Sciences (NIEHS) (4) · Karolinska Institutet (3) · Amgen (3) · University of Pittsburgh (2) · Kezar Life Sciences, Inc. (2) · Karolinska University Hospital (2) · Novartis Pharmaceuticals (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 70 — search for more.
- Adult and Juvenile MyositisRecruitingNCT000179141 country
- Natural History of Inflammatory Muscle DiseasesRecruitingNCT057388241 country
- A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)RecruitingNCT06455449Phase 329 countries
- A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory MyopathyEnrolling by invitationNCT05979441Phase 329 countries
- Environmental Risk Factors for the Anti-synthetase SyndromeRecruitingNCT012764701 country
- A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]RecruitingNCT05895786Phase 320 countries
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.RecruitingNCT06916806Phase 110 countries
- FT839 in Autoimmune DiseasesRecruitingNCT07800871Phase 1/21 country
- A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory MyopathiesRecruitingNCT06698796Phase 312 countries
- BCMA-CD19 cCAR-T for the Treatment of Refractory Inflammatory MyopathyRecruitingNCT07715136Phase 11 country
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune DiseasesRecruitingNCT07115745Phase 110 countries
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 21 country
- Rheumatology Patient Registry and BiorepositoryRecruitingNCT044020861 country
- MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)RecruitingNCT073741071 country
- CAR-T Cells in Systemic B Cell Mediated Autoimmune DiseaseRecruitingNCT06347718Phase 1/21 country
- Phase 2 Trial to Evaluate the Efficacy, Safety of Allogeneic Mitochondria (PN-101) in Patients With Refractory Polymyositis or DermatomyositisNot yet recruitingNCT07122648Phase 21 country
- Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune DiseasesRecruitingNCT06685042Phase 1/21 country
- Mesenchymal Stem Cells Infusion in Patients With Autoimmune DiseasesEnrolling by invitationNCT06888973Phase 1/21 country
- Rheumatology Diet StudyRecruitingNCT063399571 country
- Study Evaluating Efficacy and Safety of Froniglutide (PF1801) in Patients With Idiopathic Inflammatory MyopathyRecruitingNCT05833711Phase 21 country
- Environmental Risk Factors for Myositis in Military PersonnelCompletedNCT017343691 country
- A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.CompletedNCT05523167Phase 2/336 countries
- Study of M5049 in DM and PM Participants (NEPTUNIA)TerminatedNCT05650567Phase 27 countries
- Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue DiseasesCompletedNCT003416791 country
- A Phase 2 Proof of Concept Study to Evaluate the Efficacy and Safety of Daxdilimab in Participants With Dermatomyositis (DM) or Anti-synthetase Inflammatory Myositis (ASIM)CompletedNCT05669014Phase 26 countries
- Diagnostic Accuracy of Whole Body Magnetic Resonance Imaging in Inflammatory MyopathiesCompletedNCT01432613Not applicable1 country
- Muscle Function and Effects of Repetitive Task Training in Patients With Inflammatory MyopatiesCompletedNCT05027152Not applicable1 country
- Add-on Intravenous Immunoglobulins in Early MyositisActive, not recruitingNCT05832034Phase 2/31 country
- A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune DiseasesActive, not recruitingNCT06255028Phase 11 country
- Efficacy of an Individual Rehabilitation Program in Polymyositis and DermatomyositisCompletedNCT01415219Phase 21 country
- Open-label Extension to the Phase 2 Crossover Study (PRESIDIO) Evaluating KZR-616 in Patients With PM and DM.CompletedNCT04628936Phase 22 countries
- A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or DermatomyositisCompletedNCT04033926Phase 23 countries
- Efficacy and Safety of Longidaza® for the Treatment of Patients With Residual Changes in the Lungs After COVID-19CompletedNCT06383819Phase 31 country
- A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care TreatmentsTerminatedNCT03981744Phase 31 country
- Phase 1 Study of ULSC in Patients With Polymyositis (PM) and Dermatomyositis (DM)CompletedNCT04723303Early Phase 11 country
- A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune DiseasesCompletedNCT02780674Phase 11 country
- A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and DermatomyositisCompletedNCT03817424Phase 13 countries
- A Survey for Long-term Use of Prograf Capsules in Patient With Interstitial PneumoniaCompletedNCT021596511 country
- Study and Treatment of Inflammatory Muscle DiseasesCompletedNCT000012651 country
- High-intensity Strength Training in MyositisCompletedNCT04486261Not applicable1 country
- Allogeneic Mitochondria (PN-101) Transplantation for Refractory Polymyositis or DermatomyositisCompletedNCT04976140Phase 1/21 country
- Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory MyopathyCompletedNCT02971683Phase 311 countries
- Investigating Genes in Patients With Polymyositis and DermatomyositisActive, not recruitingNCT011715731 country
- Plexin D1 as a Potential Biomarker inPM/DMStatus unknownNCT05637931
- Predictor of Clinical Response to Acthar in MyositisCompletedNCT034140861 country
- Efficacy and Tolerability of BAF312 in Patients With PolymyositisTerminatedNCT01801917Phase 26 countries
- Spontaneous Coronary Artery Dissection (SCAD) and AutoimmunityCompletedNCT039411841 country
- Abatacept Treatment in Polymyositis and DermatomyositisCompletedNCT01315938Phase 22 countries
- Tocilizumab in the Treatment of Refractory Polymyositis and DermatomyositisCompletedNCT02043548Phase 21 country
- Investigation in Myositis-associated Pneumonitis of Prednisolone And Concomitant TacrolimusCompletedNCT00504348Phase 2/31 country