A Phase 2 interventional study of Active rehabilitation in Dermatomyositis and Polymyositis, sponsored by University Hospital, Lille. Completed at 5 sites in France. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-12-22.
Sponsored by University Hospital, Lille · Phase 2, Interventional, and Treatment
The purpose of this study is to evaluate the efficacy of an active rehabilitation program on disability and quality of life of patients affected by dermatomyositis and polymyositis.
Dermatomyositis (DM) and polymyositis (PM) are inflammatory disabling neuromuscular disorders. Despite partial benefit of pharmacological treatments, muscle strength, functional status and quality of life remain impaired. Although the use muscle exercises in (DM) and (PM) have been reported, its efficacy on disability and quality of life has not been proved.
Te aim of the study is to evaluate the benefit at mid term (12 months) of an active rehabilitation program administrated to patients affected by PM and DM.
Method: a 3 year prospective, multicentric, randomized controlled trial A program of 12 individual exercise sessions (3 per week during 4 weeks) is compared to conventional care. Patients are followed 12 month after the inclusion.
184 studies on the registry are indexed under Dermatomyositis; 63 are open to participants now.
This study's enrollment of 80 is above the median of 35 across 130 interventional studies indexed under Dermatomyositis.
Browse Dermatomyositis studies →University Hospital, Lille is the lead sponsor of 631 studies on the registry; 142 are open to participants now.
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Exclusion Criteria:
A program of 12 individual exercise sessions (3 per week during 4 weeks)
Other: Active rehabilitation
community based physiotherapy
A program of 12 individual exercise sessions (3 per week during 4 weeks)
HAQ score
Time frame: 6 month and 1 year after rehabilitation
Quality of life (SF36 score)
Time frame: 6 month and 1 year after rehabilitation
MFM(motor function measure)
Time frame: 6 month and one year after rehabilitation
muscle strength (MRC manual muscle testing)
Time frame: at 6 month and one year after rehabilitation
This study is completed, as verified in Dec 2014. You cannot join it, but the record below documents what was studied.
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