Ototoxicity clinical trials
The registry lists 53 studies for Ototoxicity across more than 10 countries. 17 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-08.
Status
- Completed
- 21
- Recruiting
- 13
- Status unknown
- 6
- Not yet recruiting
- 4
- Withdrawn
- 3
- Suspended
- 2
Phase
- Phase 2
- 17
- Phase 3
- 5
- Phase 1
- 4
- Phase 4
- 2
- Early Phase 1
- 1
Where
- United States
- 20
- United Kingdom
- 6
- Canada
- 6
- France
- 5
- Egypt
- 3
- Australia
- 3
Who runs them
Johns Hopkins University (4) · TC Erciyes University (2) · Children's Oncology Group (2) · Assistance Publique - Hôpitaux de Paris (2) · VA Office of Research and Development (2) · University of Nottingham (2) · Sound Pharmaceuticals, Incorporated (2) · Centre Hospitalier Universitaire Saint Pierre (1)
Studies
Recruiting first, then most recently updated. Showing 50 of 53 — search for more.
- OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTIONNot yet recruitingNCT078061231 country
- Comparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted.RecruitingNCT05936034Not applicable1 country
- Association Between Tinnitus and Hearing Loss in Locally Advanced Head and Neck Cancer Treated by Radiotherapy Alone or With Chemotherapy: a Prospective and Multicenter StudyRecruitingNCT059465771 country
- Prevention of Ototoxicity in NTM Patients Treated With IV AmikacinRecruitingNCT05730283Phase 21 country
- Maximizing Quality of Life After Cancer Through RehabilitationNot yet recruitingNCT07622407Not applicable1 country
- Long Term Outcomes After Vestibular ImplantationRecruitingNCT06500975Not applicable1 country
- Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled TrialRecruitingNCT07364747Phase 21 country
- Vestibular Implantation in Older AdultsRecruitingNCT05676944Not applicable1 country
- Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular HypofunctionRecruitingNCT05674786Not applicable1 country
- Analysis of Risk Factors for Hearing Loss in Survivors of Cancer Occurred During Childhood, Adolescence or Young AdulthoodNot yet recruitingNCT06957132Not applicable1 country
- Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck CancerNot yet recruitingNCT069294681 country
- Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular SchwannomaRecruitingNCT056414411 country
- Treatment of Radiation and Cisplatin Induced Toxicities with TempolRecruitingNCT03480971Phase 21 country
- Diagnostic of Various Ototoxicity Induced by Cancer TreatmentRecruitingNCT064900291 country
- Evaluation of the Effect of N-acetylcysteine in Preventing Cisplatin-Induced Toxicities in Cancer PatientsRecruitingNCT06297369Phase 21 country
- Video Game Hearing Tests for Remote Monitoring of OtotoxicityRecruitingNCT05847556Not applicable1 country
- Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin ChemotherapyRecruitingNCT05129748Phase 21 country
- SPI-1005 for Prevention and Treatment of Tobramycin Induced OtotoxicityCompletedNCT02819856Phase 21 country
- SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing LossWithdrawnNCT01451853Phase 21 country
- Screening for Hearing Loss After Childhood CancerCompletedNCT06036407Not applicable1 country
- Multichannel Vestibular Implant Early Feasibility StudyActive, not recruitingNCT02725463Not applicable1 country
- Statins Effect on Incidence of Side Effects of Platinum Based ChemotherapyCompletedNCT06553157Phase 1/21 country
- Head and Neck Cancer Survivorship Ototoxicity Screening (SOS)CompletedNCT05789316Not applicable1 country
- Cancer and Hearing Loss Related in ChildrenCompletedNCT024253971 country
- Investigation of the Impact of Medications Used in COVID-19 Treatment and COVID-19 Vaccine on HearingCompletedNCT072544421 country
- Sodium Thiosulfate Otoprotection During Salvage Cisplatin TherapySuspendedNCT05756660Early Phase 11 country
- Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With CisplatinCompletedNCT04541355Phase 21 country
- Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyCompletedNCT00716976Phase 33 countries
- Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced OtotoxicityTerminatedNCT04226456Phase 41 country
- Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer TreatmentCompletedNCT04262336Phase 12 countries
- Evaluation of the Effect of Rosuvastatin on Cisplatin-induced Nephrotoxicity and OtotoxicityStatus unknownNCT04817904Phase 21 country
- Prevalence and Impact on QoL From Ototoxicity in Cancer SurvivorsSuspendedNCT042709161 country
- Impact on Quality of Life of Long-term Ototoxicity in Cancer SurvivorsCompletedNCT042819531 country
- Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma TherapyCompletedNCT01848457Phase 21 country
- Randomized Trial Comparison of Ototoxicity Monitoring ProgramsCompletedNCT02099786Not applicable1 country
- Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver CancerCompletedNCT00652132Phase 31 country
- Protective Role of N-acetylcisteine From Cisplatin-induced Ototoxicity in Patients With Head and Neck CancerCompletedNCT03400709Not applicable1 country
- Dexamethasone in Preventing Hearing Loss in Patients Receiving CisplatinWithdrawnNCT02382068Not applicable
- Assessing Ear Damage in Young Cancer Patients Treated With CisplatinCompletedNCT004588873 countries
- Efficacy of Trans-tympanic Injections of a Sodium Thiosulfate Gel to Prevent Cisplatin-induced OtotoxicityTerminatedNCT02281006Phase 21 country
- Protection From Cisplatin Ototoxicity by Lactated RingersWithdrawnNCT00584155Phase 11 country
- Prevention of Cisplatin-Induced Hearing Loss by Intratympanic Dexamethasone TreatmentCompletedNCT01372904Phase 41 country
- Alpha-Lipoic Acid in Preventing Hearing Loss in Cancer Patients Undergoing Treatment With CisplatinCompletedNCT00477607Phase 2/31 country
- A Comparison of Infection Rates Between Two Surgical SitesCompletedNCT012632621 country
- Observing Young Patients With Ependymoma Undergoing Standard Combination ChemotherapyActive, not recruitingNCT006833191 country
- Aminoglycoside Plasma Level Measurement in Neonates With InfectionStatus unknownNCT016243241 country
- Protective Effect of N-acetylcysteine Against From OtotoxicityCompletedNCT01271088Phase 2/31 country
- Intratympanic Steroid Treatment For The Prevention Of Inner Ear Toxicity Associated With Systemic Treatment With Cisplatin.Status unknownNCT01285674Not applicable1 country
- Intensity-Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Decreasing Hearing Loss in Patients Who Have Undergone Surgery for Parotid TumorsStatus unknownNCT01216800Phase 31 country
- The Protective Effect of Ginkgo Biloba Extract on Cisplatin-induced Ototoxicity in HumansCompletedNCT01139281Phase 21 country