Intermittent Claudication clinical trials

The registry lists 309 studies for Intermittent Claudication across more than 10 countries. 46 are recruiting or about to start. 183 of them are mainly about Intermittent Claudication (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Status

Completed: 182
Status unknown: 46
Recruiting: 33
Terminated: 20
Not yet recruiting: 12
Withdrawn: 8

Phase

Phase 2: 34
Phase 4: 29
Phase 3: 25
Phase 1: 24

Where

United States: 119
Germany: 30
United Kingdom: 26
France: 21
Austria: 15
Belgium: 13

Who runs them

University Hospital, Angers (11) · Genovate Biotechnology Co., Ltd., (6) · Abbott Medical Devices (6) · Medtronic Endovascular (6) · Northwestern University (6) · Hull University Teaching Hospitals NHS Trust (5) · Copenhagen University Hospital at Herlev (5) · Sahlgrenska University Hospital (5)

What is being tested here

Drugs under test in Intermittent Claudication studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Metformin	1	1	2
Nicotinamide-beta-riboside	1	1	1
Perflutren	1	0	1
Fisetin	1	0	1
Cilostazol	0	1	9
Niacin	0	2	3
Aspirin	0	0	3
Ramipril	0	0	2
Sapropterin	0	0	2
Cholesterol-binding protein	0	0	2

Drug classes tested here NSAIDs 4 · Statins 3

Coming up

4phase 3 studies under way

16studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Feb 2027MetfOrmin BenefIts Lower Extremities With Intermittent Claudication · Phase 3 · VA Office of Research and Development
Nov 2026Fisetin to Reduce Senescence and Mobility Impairment in PAD · Northwestern University
Dec 2026Local And Systemic Macrophage Activation in Coronary and Peripheral Artery Disease · Maria Cecilia Hospital
Dec 2026Presence of Dural Pulsation in Patients Diagnosed With Lumbar Spinal Stenosis · Marmara University
Dec 2026CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions · Yale University
Dec 2026Study of the R3 Vascular Drug-Eluting Bioresorbable Scaffold in Treating Below the Knee Arterial Disease · R3 Vascular Inc.
Jan 2027Evaluation of the Effectiveness of Hybrid Cardiac Rehabilitation in Peripheral Artery Disease · Biruni University
Mar 2027Evaluation of Safety, Tolerability and Preliminary Efficacy of Etrinabdione in Patients With Peripheral Arterial Disease · VivaCell Biotechnology España
Jun 2027Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis · University of Nebraska
Jun 2027Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease · University of Trás-os-Montes and Alto Douro

Who these studies take

Of the 33 Intermittent Claudication studies recruiting now, 21 (64%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 1 (3%) for men only; 1 (3%) take healthy volunteers.

Recruiting studies that take each age, of 33
Age	Women	Men
10	0 (0%)	0 (0%)
18	20 (61%)	21 (64%)
30	21 (64%)	22 (67%)
40	28 (85%)	29 (88%)
50	32 (97%)	33 (100%)
65	32 (97%)	33 (100%)
75	32 (97%)	33 (100%)
85	29 (88%)	30 (91%)

Across all 309 studies, recruiting or not: 6% stop at 75 or younger and 4% at 65; 6% take children; 1% are for women only and 1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Intermittent Claudication studies take

Of 84 interventional studies with no phase under Intermittent Claudication, half reached primary completion within 41 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Interventional, no phase	41 mo17–77 · 84 studies	—	46 mo17–77 · 73 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Newly registered1

Daily Stretching to Improve Walking in Older Patients With Peripheral Artery Disease: The STRETCH PAD StudyNov 5, 2026NCT07919483

Studies

Recruiting first, then most recently updated. Showing 50 of 309. Browse all 309 → or search them.