ClinicalTrials.gg
CompletedNCT07908758Updated Nov 2, 2026

Short Term Outcomes of for Primary Small Sized Midline Ventral Hernia

An interventional study of Group I:Extended Totally Extraperitoneal Retro-muscular Repair in Outcomes, Extraperitoneal and Ventral Hernia, sponsored by Tanta University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-11-02.

Sponsored by Tanta University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 2 years 1 month after the study started (first participant enrolled Aug 2024, registered Oct 2026).
Updated Nov 2, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study is to assess the short-term outcomes of endoscopic extended totally extraperitoneal repair in primary small-sized ventral hernias, with specific regard to surgical site occurrences and hernia recurrence.

Read the detailed description

Ventral hernia repair is one of the most common surgical procedures in general surgical practice, yet the optimal treatment for ventral hernias remains debatable. Open surgical methods were the sole available techniques for ventral hernia repair until 1993.

Although the exact incidence of recurrence is unknown, it is estimated that 30-50% of patients developed recurrent hernias following primary suture repair, which decreased significantly to 1-14% with the introduction of prosthetic meshes.

Laparoscopic ventral hernia repair was first introduced in 1993 by Le Blanc and Booth, who reported the initial case managed by intraperitoneal onlay mesh , demonstrating early recovery and reduced surgical wound complications. However, adhesive bowel obstruction, mesh erosion, and enterocutaneous fistula arising from direct contact of the mesh with the viscera remained notable disadvantages of intraperitoneal onlay mesh.

espite varying approaches, debate continues between open and minimally invasive techniques regarding the optimal placement of the mesh. Current evidence-based trends suggest four general principles have emerged in contemporary ventral hernia management: mesh reinforcement, retromuscular mesh placement, primary fascial closure, and minimally invasive techniques.

The aim of this study is to assess the short-term outcomes of endoscopic extended totally extraperitoneal repair in primary small-sized ventral hernias, with specific regard to surgical site occurrences and hernia recurrence.

02

Conditions studied

  • Outcomes
  • Extraperitoneal
  • Ventral Hernia
  • Midline

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Keywords

  • Midline
  • Ventral Hernia
  • Outcomes
  • Extended Totally Extraperitoneal
  • Endoscopic
03

In context

Hernia, Ventral

230 studies on the registry are indexed under Hernia, Ventral; 45 are open to participants now.

This study's enrollment of 30 is below the median of 90 across 153 interventional studies indexed under Hernia, Ventral.

Browse Hernia, Ventral studies →

Lead sponsor

Tanta University is the lead sponsor of 1,010 studies on the registry; 321 are open to participants now.

Of its 15 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients ≥18 years of age presenting with uncomplicated primary or recurrent ventral hernia with an abdominal wall defect less than 4 cm

Exclusion criteria

Exclusion Criteria:

  • Age \<18 years
  • complicated ventral hernia
  • large ventral hernia (defect >5 cm)
  • absolute for general anesthesia
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    Group 1: Extended Totally Extraperitoneal Retro-muscular Repair

    30 patients diagnosed with uncomplicated ventral hernias who are admitted to the GIT and Laparoscopic Surgery Unit

    Procedure: Group I:Extended Totally Extraperitoneal Retro-muscular Repair

Interventions

  • ProcedureGroup I:Extended Totally Extraperitoneal Retro-muscular Repair

    30 patients diagnosed with uncomplicated ventral hernias who are admitted to the GIT and Laparoscopic Surgery

06

What researchers measure

Primary outcomes

  1. Incidence of Morbidity (Surgical Field Occurrence/Surgical Site Occurrence)

    Time frame: scheduled at 1 week, 1 month, 3 months, 6 months, and 12 months.

Secondary outcomes

  1. Hernia recurrence

    Time frame: scheduled at 1 week, 1 month, 3 months, 6 months, and 12 months.

07

Study locations

1 site
  • Tanta University
    Tanta, Egypt
08

References and documents

Individual participant data

Plan to share: Yes — It will be available if it needed

Supporting information: Study protocol, Informed consent form

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Aug 2024 to primary completion in Jul 2025, 11 months.

Of 75 non-industry interventional studies with no phase under Hernia, Ventral, half reached primary completion within 33 months of starting (the median), counting those still running; a quarter within 19 and three quarters within 48. This study's 11 months is below that.

Counting every sponsor, half of 88 studies reached it within 37 months; a quarter within 19 and three quarters within 56.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 24, 2026
First posted
Nov 2, 2026
StartActual
Aug 30, 2024
Primary completionActual
Jul 30, 2025
CompletionActual
Jul 30, 2025
Last update
Nov 2, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 2, 2026
Show all 1 update
  1. Nov 2, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07908758
Lead sponsor
Tanta University
Responsible party
Ahmed Mohamed Moussa (Resident, Tanta University) — Principal investigator
First posted
Nov 2, 2026
Start date
Aug 30, 2024
Primary completion
Jul 30, 2025
Completion
Jul 30, 2025
Last update
Nov 2, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.

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