Hernia, Abdominal clinical trials
The registry lists 82 studies for Hernia, Abdominal across more than 10 countries. 19 are recruiting or about to start. 45 of them are mainly about Hernia, Abdominal (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 4 narrower conditions too, such as Hernia, Inguinal: 886 studies, 156 open.
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Who runs them
The Cleveland Clinic (4) · Algemeen Ziekenhuis Maria Middelares (3) · Azienda Sanitaria Locale Napoli 2 Nord (2) · Medtronic - MITG (2) · Bispebjerg Hospital (2) · Mansoura University (2) · Erasmus Medical Center (2) · Hospital de Granollers (1)
What is being tested here
Drugs under test in Hernia, Abdominal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Botulinum toxin type A | 1 | 0 | 3 |
| Nalbuphine | 1 | 1 | 1 |
| Acetaminophen | 0 | 0 | 2 |
| Onabotulinum toxin A | 0 | 0 | 1 |
| Ibuprofen | 0 | 0 | 1 |
| Oxycodone | 0 | 0 | 1 |
| Fibrin Tissue Adhesive | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5, phase 3 first
- Jan 2027Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management · Phase 3 · Dr. Asma Abdus Salam
- Jan 2027Experience of IPOM Technique in Laparoscopic Ventral Hernia Repair · Sohag University
- Mar 2027Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair · University of South Florida
- May 2027Abdominal Wall Tension in Patients Undergoing Ventral Hernia Repair Without Component Separation · The Cleveland Clinic
- Aug 2027Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair · Minia University
Who these studies take
Of the 10 Hernia, Abdominal studies recruiting now, 7 (70%) set no upper age limit and 3 (30%) stop at 75 or younger. 2 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (20%) | 2 (20%) |
| 18 | 10 (100%) | 10 (100%) |
| 30 | 10 (100%) | 10 (100%) |
| 40 | 10 (100%) | 10 (100%) |
| 50 | 10 (100%) | 10 (100%) |
| 65 | 10 (100%) | 10 (100%) |
| 75 | 8 (80%) | 8 (80%) |
| 85 | 7 (70%) | 7 (70%) |
Across all 82 studies, recruiting or not: 24% stop at 75 or younger and 17% at 65; 15% take children; 4% are for women only and 1% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hernia, Abdominal studies take
Of 31 interventional studies with no phase under Hernia, Abdominal, half reached primary completion within 31 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 31 mo13–60 · 31 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered3
- Robotic vs Open Retromuscular Abdominal Wall Hernia RepairNov 9, 2026NCT07925112
- Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral HerniaOct 26, 2026NCT07896278
- Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia RepairOct 15, 2026NCT07874724
Studies
Recruiting first, then most recently updated. Showing 50 of 82. Browse all 82 → or search them.
- Population Based Strategies for Standardized Surgical CareNot yet recruitingNCT07106541Not applicable1 country
- Preoperative Weight Loss for Open Abdominal Wall ReconstructionRecruitingNCT05925959Not applicable1 country
- Robotic vs Open Retromuscular Abdominal Wall Hernia RepairNot yet recruitingNCT07925112
- Preoperative BOTOX® Injection for Large Ventral Hernia RepairRecruitingNCT07220382Phase 41 country
- Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia RepairNot yet recruitingNCT07874724Not applicable1 country
- Image-Guided Herniorrhaphy StudyNot yet recruitingNCT07267494Not applicable1 country
- Experience of IPOM Technique in Laparoscopic Ventral Hernia RepairNot yet recruitingNCT07792135
- Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia RepairRecruitingNCT07720154Not applicable1 country
- Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain ManagementRecruitingNCT06996561Phase 2/31 country
- Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia TreatmentRecruitingNCT07476560Not applicable1 country
- Hernia Repair Using Rectus Fascia AllograftNot yet recruitingNCT07326826
- Abdominal Wall TransplantRecruitingNCT03310905Not applicable1 country
- The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWRRecruitingNCT04906408Not applicable1 country
- Effects of a Multicomponent Training Program on Health Outcomes in Patients with Abdominal Wall HerniaNot yet recruitingNCT06872554Not applicable
- Abdominoplasty with Ventral Hernia Repair Versus Hernioplasty .Not yet recruitingNCT05792839Not applicable
- Long Term Outcomes Following Hernia Repair With MeshRecruitingNCT045783401 country
- Relating Abdominal Complications With Peritoneal Pressure Estimation and ReportingNot yet recruitingNCT060609511 country
- Clinical Study of Hernia Ring Closure Method in Laparoscopic Abdominal Wall Hernia RepairRecruitingNCT05661097Not applicable1 country
- Web-based International Register of Emergency Surgery and TraumaRecruitingNCT036437181 country
- Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral HerniaCompletedNCT07896278Not applicable1 country
- Optimization of Surgical Treatment of Patients With Incisional Ventral HerniasCompletedNCT05734222Not applicable1 country
- Safety and Clinical Performance of a Biological Matrix Used in Abdominal Wall ReconstructionActive, not recruitingNCT045805111 country
- Occupational Claims Due to HerniaCompletedNCT078310051 country
- Robotic Versus Open Comparison in the Surgical Treatment of Wide Abdominal Wall heRnias (ROCSTAR)WithdrawnNCT05575141Not applicable
- Abdominal Wall Tension in Patients Undergoing Ventral Hernia Repair Without Component SeparationActive, not recruitingNCT060515781 country
- Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral HerniaActive, not recruitingNCT06449378Not applicable3 countries
- Tirzepatide-Based Prehabilitation Before Elective Ventral and Incisional Hernia Repair in Patients With ObesityCompletedNCT076385921 country
- Serratus Intercostal Block Versus Epidural/Port Infiltration Analgesia in Eventration: Prospective Non Inferiority StudyCompletedNCT06014749Phase 41 country
- Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term OutcomeCompletedNCT05906017Not applicable1 country
- Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair ScenariosCompletedNCT07360691Not applicable1 country
- Complication Rate of Onlay vs Sublay Mesh Repair in Incisional HerniaCompletedNCT07401446Not applicable1 country
- Light vs Heavy Weighted Mesh Repair in Primary Abdominal Hernia in Terms of Surgical Site InfectionCompletedNCT06644612Not applicable1 country
- Comparison Between eTEP-RS vs IPOM PLUSCompletedNCT07055464Not applicable1 country
- T-GENVIH-003 LTFU (Long Term Follow Up) StudyCompletedNCT060346521 country
- Virtual Reality on Pulmonary Function After Upper Abdominal SurgeriesActive, not recruitingNCT06301126Not applicable1 country
- Versius or Laparoscopic Abdominal Hernia REpairWithdrawnNCT05253586
- Effect of Different Ventilation Modes on POCD in Elderly Patients with Abdominal Wall HerniaCompletedNCT06764745Not applicable1 country
- A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation TechniqueWithdrawnNCT05606757Phase 21 country
- ENHANCE: A Prospective EvaluatioN of Permacol™ in tHe Repair of Complex AbdomiNal Wall CasEsCompletedNCT012685145 countries
- Remifentanil in Deep vs Moderate Neuromuscular Blocks During Surgical Pleth Index-guided Anesthesia for Laparoscopic HerniorrhaphyCompletedNCT04022733Not applicable1 country
- Outcomes of Trasversus Abdominis Release for Complex Abdominal Wall HerniaCompletedNCT061112871 country
- Prevention of Incisional Hernia After Elective Open Abdominal Aortic Aneurysm (AAA) RepairTerminatedNCT01189708Not applicable1 country
- Magnitude, Types, and Associated Factors of External Abdominal Hernias Among Adult Patients Visiting the Surgical Outpatient Department at Hiwotfana Comprehensive Specialized Hospital and Jugol Regional Hospital, Eastern Ethiopia: A Cross-Sectional StudyCompletedNCT059727071 country
- Study Exploring the Effect of Music on Pain After Ventral Hernia SurgeryCompletedNCT05374096Not applicable1 country
- Prophylaxis of Surgical Wound Infection With Topical AntibioticsStatus unknownNCT04476212Not applicable1 country
- Ventral Abdominal Hernia Repair With Self Adhering, Atraumatic MeshCompletedNCT04435340Not applicable1 country
- Physiologic Tension of the Abdominal WallCompletedNCT051631841 country
- Quality of Life Evaluations in Patients With Abdominal Wall HerniasCompletedNCT011154001 country
- To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children SurgeryStatus unknownNCT05308771Not applicable1 country
- Stepwise for the Treatment of Lateral Incisional HerniasCompletedNCT052052131 country