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Heartburn clinical trials

The registry lists 154 studies for Heartburn across more than 10 countries. 12 are recruiting or about to start. 46 of them are mainly about Heartburn (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
113
Status unknown
18
Recruiting
8
Terminated
6
Not yet recruiting
3
Active, not recruiting
3

Phase

Phase 4
32
Phase 3
31
Phase 2
19
Phase 1
14
Early Phase 1
1

Where

United States
76
Germany
7
China
6
Netherlands
5
Spain
4
Vietnam
4

Who runs them

AstraZeneca (24) · Takeda (8) · Novartis (7) · Bayer (5) · Phathom Pharmaceuticals, Inc. (4) · Mayo Clinic (4) · Eisai Inc. (3) · Southern Arizona VA Health Care System (3)

What is being tested here

Drugs under test in Heartburn studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Acetic Acid101
Esomeprazole0319
Dexlansoprazole059
Rabeprazole047
Omeprazole015
Lansoprazole025
Pantoprazole014
Alginates013
Vonoprazan013
Lesogaberan003

Drug classes tested here Proton pump inhibitors (PPIs) 44

Coming up

1phase 3 study under way
6studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6, phase 3 first

Who these studies take

Of the 8 Heartburn studies recruiting now, 5 (63%) set no upper age limit and 3 (38%) stop at 75 or younger. 2 (25%) take children under 18. 1 (13%) are for women only and 0 (0%) for men only; 1 (13%) take healthy volunteers.

Recruiting studies that take each age, of 8
AgeWomenMen
100 (0%)0 (0%)
188 (100%)7 (88%)
308 (100%)7 (88%)
408 (100%)7 (88%)
507 (88%)6 (75%)
655 (63%)5 (63%)
755 (63%)5 (63%)
855 (63%)5 (63%)

Across all 154 studies, recruiting or not: 44% stop at 75 or younger and 19% at 65; 8% take children; 2% are for women only and 2% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Heartburn studies take

Of 26 interventional studies with no phase under Heartburn, half reached primary completion within 15 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase15 mo10–35 · 26 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 154. Browse all 154 → or search them.