Disruptive, Impulse Control, and Conduct Disorders clinical trials
The registry lists 56 studies for Disruptive, Impulse Control, and Conduct Disorders across more than 10 countries. 17 are recruiting or about to start. 24 of them are mainly about Disruptive, Impulse Control, and Conduct Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-22. Counting its 3 narrower conditions too, such as Gambling: 261 studies, 67 open.
Get an email when these change. Save the Disruptive, Impulse Control, and Conduct Disorders studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
University of Chicago (7) · Ohio State University (5) · University Hospital, Clermont-Ferrand (4) · University of Minnesota (3) · University Hospital, Strasbourg, France (2) · Hospices Civils de Lyon (2) · Boehringer Ingelheim (2) · Assistance Publique - Hôpitaux de Paris (2)
What is being tested here
Drugs under test in Disruptive, Impulse Control, and Conduct Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pimavanserin | 1 | 0 | 2 |
| Endotoxins | 1 | 0 | 1 |
| Ethanol | 1 | 0 | 1 |
| Nitrous Oxide | 1 | 0 | 1 |
| Naltrexone | 0 | 0 | 3 |
| Acetylcysteine | 0 | 0 | 2 |
| Clonidine | 0 | 0 | 1 |
| SRX246 | 0 | 0 | 1 |
| Inositol | 0 | 0 | 1 |
| Memantine | 0 | 0 | 1 |
Drug classes tested here Antipsychotics 1 open · Opioid antagonists 4 · SSRIs 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Jan 2027Pimavanserin and Aggression and Social Cognition. · Ohio State University
- May 2027rTMS Over the Dorsolateral Prefrontal Cortex for the Treatment of Impulse Control Disorders in Parkinson's Disease · West Virginia University
- Jul 2027STIMPulseControl Ancillary Speech Study · Steffen Paschen
- Jul 2027Bilateral Subthalamic Stimulation in PD Patients With Impulse Control Disorders - STIMPulseControl · University of Kiel
- Aug 2027Effect of Nitrous Oxide on Aggression. · Ohio State University
- Oct 2027Neurostimulation Versus Therapy for Problems With Emotions · Duke University
- Nov 2027Feasibility of Accelerated, Personalized rTMS as an Adjuvant for Impulse Control Disorders: a Pilot Study · M.D. Anderson Cancer Center
Who these studies take
Of the 15 Disruptive, Impulse Control, and Conduct Disorders studies recruiting now, 4 (27%) set no upper age limit and 10 (67%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 8 (53%) | 8 (53%) |
| 30 | 14 (93%) | 14 (93%) |
| 40 | 14 (93%) | 14 (93%) |
| 50 | 15 (100%) | 15 (100%) |
| 65 | 9 (60%) | 9 (60%) |
| 75 | 6 (40%) | 6 (40%) |
| 85 | 4 (27%) | 4 (27%) |
Across all 56 studies, recruiting or not: 71% stop at 75 or younger and 54% at 65; 13% take children; 0% are for women only and 2% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 50 of 56. Browse all 56 → or search them.
- STIMPulseControl Ancillary Speech StudyRecruitingNCT06561919Not applicable3 countries
- Bilateral Subthalamic Stimulation in PD Patients With Impulse Control Disorders - STIMPulseControlRecruitingNCT06498349Not applicable3 countries
- Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's DiseaseRecruitingNCT07505394Not applicable1 country
- Feasibility of Accelerated, Personalized rTMS as an Adjuvant for Impulse Control Disorders: a Pilot StudyRecruitingNCT06639594Phase 11 country
- Controlled Evaluation of an Exercise Program for Overweight AdolescentsEnrolling by invitationNCT06923865Not applicable1 country
- Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Counteract Dopaminergic Desensitization and Neuropsychiatric Complications in Parkinson's DiseaseRecruitingNCT07151378Phase 31 country
- PET-MRI of Reward System in Parkinson's Disease With RBDRecruitingNCT07213219Not applicable1 country
- rTMS Over the Dorsolateral Prefrontal Cortex for the Treatment of Impulse Control Disorders in Parkinson's DiseaseRecruitingNCT06237868Not applicable1 country
- Inflammatory Challenge in Human Aggression.RecruitingNCT06665074Phase 21 country
- LHC-CIDI-5 in Hong KongRecruitingNCT068045251 country
- Neurostimulation Versus Therapy for Problems With EmotionsRecruitingNCT05712057Not applicable1 country
- Frontosubthalamic Networks in Parkinson's Disease.RecruitingNCT06485986Not applicable1 country
- Neural Correlates During Alcohol IntoxicationRecruitingNCT06118580Phase 21 country
- Effect of Nitrous Oxide on Aggression.RecruitingNCT06118567Phase 21 country
- Pimavanserin and Aggression and Social Cognition.RecruitingNCT05895513Phase 21 country
- Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist, to Treat Impulse Control Disorders in Parkinson's Disease.Not yet recruitingNCT067545531 country
- Maladaptive Anger TreatmentRecruitingNCT06275607Not applicable1 country
- Study of the Efficacy of N-acetylcysteine (NAC) on Impulse Control DisordersTerminatedNCT03146130Phase 31 country
- Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist, to Treat Impulse Control Disorders in Parkinson's Disease.CompletedNCT03947216Phase 21 country
- Study of Clonidine Efficacy for the Treatment of Impulse Control Disorders in Parkinson's Disease:CompletedNCT03552068Phase 21 country
- Objective Assessment of Behavioural Disorders in PDActive, not recruitingNCT046115811 country
- Psychotherapy for Intermittent Explosive DisorderCompletedNCT00667212Not applicable1 country
- Safety, Tolerability and Activity of SRX246 in Adults With Intermittent Explosive DisorderCompletedNCT02055638Phase 1/21 country
- Circadian Character of Food Compulsions and Impulses Control Disorders in Parkinsonian Patients With and Without Resting Leg SyndromeCompletedNCT03818243Not applicable1 country
- Inositol in TrichotillomaniaCompletedNCT01875445Phase 21 country
- Drug Treatment for Pathologic Gambling DisorderCompletedNCT00053677Phase 31 country
- N-Acetyl Cysteine in Pathologic Skin PickingCompletedNCT01063348Phase 21 country
- Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Intermittent Explosive DisorderTerminatedNCT03420222Phase 21 country
- Testing a New Therapy for TrichotillomaniaCompletedNCT00872742Phase 21 country
- Clinical Response of Impulsivity After Brain Stimulation in Parkinson's DiseaseStatus unknownNCT04811807
- Memantine in the Treatment of KleptomaniaCompletedNCT00880685Phase 21 country
- A Comparison of Fluoxetine and Divalproex for the Treatment of Intermittent Explosive DisorderCompletedNCT00078754Phase 21 country
- A Cognitive Bias Modification RCT for AggressionStatus unknownNCT04819230Not applicable1 country
- Remission of ICD by Switching Dopamine Agonist to Levodopa/CarbidopaCompletedNCT01683253Phase 41 country
- Restoring Cognitive Control (ReCon) in Acute Nicotine WithdrawalCompletedNCT03887429Phase 21 country
- Serotonin in Impulse Control Disorders in Parkinson's DiseaseStatus unknownNCT03970239Not applicable1 country
- Double-Blind Naltrexone in KleptomaniaCompletedNCT00332579Phase 21 country
- Psychiatric and Cognitive Manifestations of Parkinson's DiseaseCompletedNCT003606331 country
- Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in AdolescentsCompletedNCT01111734Phase 11 country
- Fingerprinting of ImpulsivityCompletedNCT027221741 country
- fMRI in ImpulsivityCompletedNCT027551811 country
- Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive DisorderCompletedNCT02048241Phase 41 country
- Better Understand Children and Adolescents' Intrafamilial Oppositional Defiant DisorderCompletedNCT034475351 country
- Effects of Non-invasive Brain Stimulation in Impulse Control DisordersStatus unknownNCT02927002Not applicable1 country
- Acamprosate in the Treatment of Pathological GamblingCompletedNCT00571103Phase 4
- Behavioural Addiction and Genetics in Parkinson's DiseaseCompletedNCT023193951 country
- Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label StudyStatus unknownNCT02934919Phase 21 country
- Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone.CompletedNCT00399698Phase 31 country
- Exploration of Mesocorticolimbic Pathway in Impulse Control Disorders in Parkinson's Disease: Study Using Tensor Diffusion Imaging and Tractography.Status unknownNCT02796040Not applicable1 country
- Naltrexone for Impulse Control Disorders in Parkinson's DiseaseCompletedNCT01052831Phase 41 country