BiologicalDrug
Endotoxins clinical trials
- studies test it
- 23
- open now
- 3
- in phase 3
- 0
- first study started
- 2003
Keep track of what changes. Save the Endotoxins studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
23 studies that test it; most in 2010 (3)
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2004 | 1 |
| 2007 | 2 |
| 2008 | 1 |
| 2010 | 3 |
| 2011 | 1 |
| 2012 | 1 |
| 2014 | 2 |
| 2015 | 2 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 5
- Phase 1
- 9
- Phase 2
- 6
- No phase
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 23
University of California, Los Angeles (7) · Washington University School of Medicine (3) · National Institutes of Health Clinical Center (CC) (2) · Karolinska Institutet (2) · Yale University (1) · Michael Irwin, MD (1) · University of North Carolina, Chapel Hill (1) · National Cancer Institute (NCI) (1)
Often tested with
Tested in the same studies.
Carbon Monoxide (1) · Interleukin-4 (1) · Keyhole limpet hemocyanin (1) · Epinephrine (1) · Tumor Necrosis Factor-alpha (1)
Studies
Open first, then newest update. How each study uses Endotoxins is read from its arms, and is right about nine times in ten.
Testing it · 23
- Effects of Bronchial Segmental Endotoxin Instillation in HumansEnrolling by invitationPhase 2National Institutes of Health Clinical Center (CC)NCT02392442Written as Endotoxin
- Endotoxin Exposure to Examine the Role of Inflammation in Alcohol UseNot yet recruitingPhase 2University of California, Los AngelesNCT07452146Written as Endotoxin
- Inflammatory Challenge in Human Aggression.RecruitingPhase 2Ohio State UniversityNCT06665074Written as Endotoxin (E. coli O:113, Reference Endotoxin)
- Sleep and Healthy Aging Research on Depression for Younger WomenCompletedPhase 1University of California, Los AngelesNCT03848715Written as Endotoxin
- Aging and Reward System Response to Inflammation and Anxiety StudyCompletedPhase 1University of California, Los AngelesNCT05363527Written as Endotoxin
- Effect of Endotoxin on Alcohol ConsumptionCompletedPhase 2Yale UniversityNCT04527185Written as Endotoxin
- An Inflammatory Challenge Using EndotoxinCompletedPhase 2University of California, Los AngelesNCT04310423Written as Endotoxin
- Sleep and Healthy Aging Research for Depression (SHARE-D) StudyCompletedPhase 1Michael Irwin, MDNCT03256760Written as Endotoxin
- Sleep Health, Inflammation, and Emotion StudyCompletedEarly Phase 1University of California, Los AngelesNCT02270619Written as Endotoxin
- Carbon Monoxide to Prevent Lung InflammationCompletedPhase 1National Institutes of Health Clinical Center (CC)NCT00094406Written as Endotoxin
- Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART)CompletedPhase 1University of North Carolina, Chapel HillNCT03623022Written as Clinical Center Reference Endotoxin (CCRE)
- Assessing NOS Uptake With PET Imaging in Lung InflammationCompletedEarly Phase 1Washington University School of MedicineNCT02151552Written as Endotoxin (E. coli O:113, Reference Endotoxin)
- Inflammation and Brain Function - Main StudyCompletedNot applicableKarolinska InstitutetNCT03551184Written as Endotoxin
- Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the BloodCompletedPhase 1/2National Cancer Institute (NCI)NCT00923910Written as Endotoxin
- Dose-Related Inflammatory Effects of Intravenous Endotoxin in HumansCompletedPhase 1Robert J Noveck, M.D.NCT02789241Written as Endotoxin
- Inflammation and the Metabolic Syndrome in HumansCompletedNot applicableUniversity of PennsylvaniaNCT00954824Written as Endotoxin (LPS)
- Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual DifferencesCompletedNot applicableKarolinska InstitutetNCT02529592Written as Endotoxin
- The Effects of Epinephrine in Endotoxemia in Normal VolunteersCompletedPhase 1Rutgers, The State University of New JerseyNCT00753402Written as Endotoxin, Epinephrine
- Inflammation-Induced Depressed Mood: The Role of Social Neurocognitive MechanismsCompletedEarly Phase 1University of California, Los AngelesNCT01671150Written as endotoxin
- Quantifying Airway Inflammation With Radiologic TestsCompletedEarly Phase 1Washington University School of MedicineNCT00741013Written as Endotoxin
See all 23 studies that test Endotoxins →
Given in every arm · 8 — Endotoxins is usual care beside what is tested
- The Antiplatelet and Immune Response TrialCompletedPhase 4Sheffield Teaching Hospitals NHS Foundation TrustNCT01846559Written as Endotoxin
- Adrecizumab-LPS StudyCompletedPhase 1Adrenomed AGNCT03083171Written as Endotoxin
- PK/PD of EA-230 During EndotoxemiaCompletedPhase 1Radboud University Medical CenterNCT02629874Written as Endotoxin
- The Role of the Gut Microbiota in the Systemic Immune Response During Human EndotoxemiaCompletedNot applicableAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT02127749Written as Endotoxin
- Effects of Iron Loading and Iron Chelation Therapy on Innate Immunity During Human EndotoxemiaCompletedNot applicableRadboud University Medical CenterNCT01349699Written as endotoxin
- In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR IICompletedPhase 3Radboud University Medical CenterNCT01766414Written as Endotoxin
- Effect of Intrapulmonary Recombinant Human Activated Protein C (APC) on Coagulation and Inflammation After Lipopolysaccharide (LPS)CompletedNot applicableAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT00943267Written as Endotoxin
- Anti-inflammatory Effects of GTS-21 After LPSCompletedNot applicableRadboud University Medical CenterNCT00783068Written as Lipopolysaccharide E. Coli 113:H 10:K negative