Drug
Nitrous Oxide clinical trials
Also written N2O.
- studies test it
- 102
- open now
- 14
- in phase 3
- 11
- first study started
- 1993
Keep track of what changes. Save the Nitrous Oxide studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
101 studies that test it; most in 2016 (11)
| Year | Studies |
|---|---|
| 1993 | 2 |
| 1994 | 3 |
| 1995 | 3 |
| 1996 | 1 |
| 1997 | 2 |
| 1998 | 1 |
| 2000 | 1 |
| 2003 | 2 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 3 |
| 2009 | 2 |
| 2011 | 1 |
| 2012 | 6 |
| 2013 | 6 |
| 2014 | 2 |
| 2015 | 3 |
| 2016 | 11 |
| 2017 | 6 |
| 2018 | 3 |
| 2019 | 7 |
| 2021 | 11 |
| 2022 | 4 |
| 2023 | 4 |
| 2024 | 3 |
| 2025 | 2 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 10
- Phase 1
- 7
- Phase 2
- 25
- Phase 3
- 11
- Phase 4
- 26
- No phase
- 26
What it is tested for
Each study’s main condition, where its own words name it.
- Pain
- 3
Who runs them
Industry 3 · Other 99
University of Chicago (14) · Washington University School of Medicine (5) · The Cleveland Clinic (4) · Beth Israel Deaconess Medical Center (3) · Stanford University (3) · Albert Einstein Healthcare Network (3) · Assistance Publique - Hôpitaux de Paris (2) · Columbia University (2)
Often tested with
Tested in the same studies.
Oxygen (7) · Midazolam (5) · Sevoflurane (4) · Dexmedetomidine (3) · Propofol (2) · Remifentanil (2) · Fentanyl (2) · Meperidine (1)
Studies
Open first, then newest update. How each study uses Nitrous Oxide is read from its arms, and is right about nine times in ten.
Testing it · 102
- Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial-Not yet recruitingPhase 2University Hospital, ToursNCT06382389Written as EMONO
- A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing ChangesRecruitingEarly Phase 1University of ManitobaNCT03695887Written as Nitrous Oxide Inhalant Product
- NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain CircuitsRecruitingPhase 1Washington University School of MedicineNCT02994433Written as Nitrous Oxide
- Use of Nitrous Oxide for Pain and Anxiety Management During Cervical Cerclage RemovalNot yet recruitingNot applicableKaplan Medical CenterNCT07491874Written as Inhaled nitrous oxide
- Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of VasectomyRecruitingPhase 4Beth Israel Deaconess Medical CenterNCT05895383Written as Nitrous oxide
- A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox InjectionsNot yet recruitingPhase 4TriHealth Inc.NCT07387315Written as Pro-Nox Nitrous Oxide/Oxygen Delivery System
- Nitrous Oxide- Suicidal IdeationEnrolling by invitationPhase 1Washington University School of MedicineNCT03736538Written as Nitrous Oxide
- Sustained Mood Improvement With Laughing Gas ExposureNot yet recruitingPhase 3Women's College HospitalNCT07262008Written as Inhalation of Nitrous oxide (Laughing gas) + intravenous saline
- A Trial of Self-Adjusted Nitrous Versus Placebo During Office VasectomyRecruitingEarly Phase 1Alexandra J. Berger Eberhardt, MDNCT07245628Written as Nitrous Oxide
- Efficacy of Nitrous Oxide in OCD: Pilot StudyRecruitingPhase 2Stanford UniversityNCT03826693Written as Nitrous Oxide
- Anxiolysis for Laceration Repair in ChildrenRecruitingPhase 3London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sNCT05383495Written as Nitrous oxide
- Effect of Nitrous Oxide on Aggression.RecruitingPhase 2Ohio State UniversityNCT06118567Written as Nitrous oxide
- Efficacy of Remifentanil in Preventing Emergence AgitationRecruitingNot applicableSaglik Bilimleri Universitesi Gazi Yasargil Training and Research HospitalNCT06539013Written as N2O
- Treatment of Suicidal Ideation in the Emergency Department Using Nitrous OxideNot yet recruitingPhase 2University Hospital, ToursNCT06430489Written as Nitrous oxide
- Intracervical Balloon Placement With Nitrous Oxide AdministrationWithdrawnPhase 3Jefferson DrapkinNCT06498908Written as Nitrous oxide
- Nitrous Oxide NeuroimagingCompletedEarly Phase 1Keith M VogtNCT06702631Written as Nitrous oxide
- Nitrous Oxide for Analgesia During Nasogastric Tube Placement in Young ChildrenCompletedNot applicableAssistance Publique - Hôpitaux de ParisNCT04008628Written as Nitrous Oxide
- Nitrous Oxide Induction Induces Amnesia in Pediatric PatientsCompletedNot applicableState University of New York at BuffaloNCT02050152Written as Nitrous Oxide 0%
- Antidepressant Effects of Nitrous OxideWithdrawnPhase 2University of ChicagoNCT05357040Written as Nitrous oxide gas for inhalation
- Nitrous Oxide as Treatment for FibromyalgiaWithdrawnPhase 2University of ChicagoNCT05357066Written as Nitrous oxide gas for inhalation
See all 102 studies that test Nitrous Oxide →
Given in every arm · 10 — Nitrous Oxide is usual care beside what is tested
- Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft SurgeryRecruitingNot applicableIva SmiljanićNCT07557576Written as Nitrous Oxide/Oxygen
- Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial SurgeryCompletedPhase 1Albert Einstein College of MedicineNCT06867068Written as Nitrous oxide
- Trial- Dysphagia From ETT or GI EndoscopyWithdrawnNot applicableBaylor College of MedicineNCT02460055Written as sevoflurane, nitrous oxide and oxygen
- Dexmedetomidine and Propofol for Pediatric MRI SedationCompletedPhase 4Medical College of WisconsinNCT03513757Written as Nitrous Oxide
- Analgesic Effect of IV Acetaminophen in TonsillectomiesCompletedPhase 2Nationwide Children's HospitalNCT01691690Written as Nitrous Oxide/Oxygen
- Isoflurane at Subanesthetic Concentrations - 6CompletedPhase 2University of ChicagoNCT00000254Written as 40% Nitrous oxide
- Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14CompletedNot applicableUniversity of ChicagoNCT00000262Written as 30% Nitrous oxide
- Effects of Combined Alcohol and Nitrous Oxide Intake - 15CompletedNot applicableUniversity of ChicagoNCT00000263Written as 30% Nitrous oxide
- Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16CompletedNot applicableUniversity of ChicagoNCT00000264Written as 30% Nitrous oxide
- Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer SurgeryStatus unknownNot applicableHillel Yaffe Medical CenterNCT02326727Written as Nitrous Oxide
As the comparator · 4 — what is tested is compared with Nitrous Oxide
- Virtual Reality Games in Pediatric SurgeryRecruitingNot applicableInsel Gruppe AG, University Hospital BernNCT05510141Written as Nitrous oxide
- Virtual Reality Hypnosis Versus Inhaled Nitrous Oxide in Anterior Shoulder Dislocation Reduction: an Open Multicenter Randomized Controlled TrialStatus unknownNot applicableCHU de ReimsNCT05388942Written as Nitrous oxide
- Distraction and Nitrous Oxide for Venous PunctureCompletedNot applicableUniversity Hospital, GenevaNCT04185233Written as Nitrous Oxide
- Open Randomized Controlled Trial to Evaluate the Efficacy and Safety of Remifentanil Versus Nitrous Oxide in External Cephalic Version at Term in Singleton Pregnancy in Breech PresentationCompletedPhase 3Hospital de CrucesNCT01735669Written as Nitrous Oxide
Codes
What other systems call Nitrous Oxide · ClinicalTrials.gg INT007904
- MeSH (NLM) D009609Nitrous OxideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) K50XQU1029NITROUS OXIDEConfirmed FDA, NLM, Wikidata
- RxNorm 7486Confirmed FDA, Wikidata
- Wikidata Q905750nitrous oxideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73617Nitrous OxideOne source FDA
- DrugBank DB06690One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D009609 | Nitrous Oxide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | K50XQU1029 | NITROUS OXIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 7486 | — | Confirmed FDA, Wikidata |
| Wikidata | Q905750 | nitrous oxide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73617 | Nitrous Oxide | One source FDA |
| DrugBank | DB06690 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.