Calcinosis clinical trials
The registry lists 91 studies for Calcinosis across more than 10 countries. 19 are recruiting or about to start. 19 of them are mainly about Calcinosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 4 narrower conditions too, such as Vascular Calcification: 250 studies, 67 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Taiwan University Hospital (4) · Mayo Clinic (3) · University of Edinburgh (3) · University Hospital, Angers (2) · University of Zurich (2) · Shockwave Medical, Inc. (2) · Johns Hopkins University (2) · Sanifit Therapeutics S. A. (2)
What is being tested here
Drugs under test in Calcinosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Sodium thiosulfate | 1 | 2 | 6 |
| Colchicine | 1 | 1 | 2 |
| SNF472 | 0 | 0 | 2 |
| Efmirenpase alfa | 0 | 0 | 1 |
| Probiotic | 0 | 0 | 1 |
| Allopurinol | 0 | 0 | 1 |
| Treprostinil | 0 | 0 | 1 |
| Magnesium Oxide | 0 | 0 | 1 |
| Ataciguat | 0 | 0 | 1 |
| Inulin | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8, phase 3 first
- Dec 2026Colchicine and Inflammation in Aortic Stenosis · Phase 3 · Radboud University Medical Center
- Nov 2026TRAns-Femoral Access Intravascular Lithotripsy Comparison With PTA in TAVI · Rede Optimus Hospitalar SA
- Nov 2026Shockwave™ vs Surgical Endarterectomy for Calcified Severe Common Femoral Artery Stenosis: Comparison of Efficacy, Safety and Long-Term Outcomes · Baylor Research Institute
- Dec 2026Intravascular Lithotripsy for Acute Stent Under-expansion in Calcified Coronary Lesions · Xuzhou Third People's Hospital
- Dec 2026The Added Value of Contrast Enhanced Mammography to Standard Mammography in Assessing the Extent of DCIS · Clinical Hospital Center Rijeka
- Oct 2027Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study) · Shockwave Medical, Inc.
- Nov 2027Angioplasty With Shockwave IVL Catheter System in Femoropopliteal Lesions · Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology
- Nov 2027ClinicAL outComes of IntraVascular Lithotripsy Combined With Conventional Lesion Preparation in Patients With Moderate to Severe Coronary Artery Calcification · Second Affiliated Hospital, School of Medicine, Zhejiang University
Who these studies take
Of the 11 Calcinosis studies recruiting now, 10 (91%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 10 (91%) | 10 (91%) |
| 30 | 10 (91%) | 10 (91%) |
| 40 | 10 (91%) | 10 (91%) |
| 50 | 10 (91%) | 10 (91%) |
| 65 | 11 (100%) | 11 (100%) |
| 75 | 11 (100%) | 11 (100%) |
| 85 | 11 (100%) | 11 (100%) |
Across all 91 studies, recruiting or not: 19% stop at 75 or younger and 14% at 65; 9% take children; 12% are for women only and 1% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Calcinosis studies take
Of 19 interventional studies with no phase under Calcinosis, half reached primary completion within 31 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 31 mo12–47 · 19 studies | — | — |
| Observational | 38 mo20–73 · 14 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 91. Browse all 91 → or search them.
- REducing Systemic Inflammation With LOw-dose Colchicine to ImproVE Cardiovascular Calcification in Chronic Kidney Disease: A Pilot Randomized Open-Label TrialNot yet recruitingNCT07654231Phase 21 country
- Advanced Ultrasound Signal Processing of Suspicious Breast ImagesEnrolling by invitationNCT072068881 country
- Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)RecruitingNCT07062471Not applicable1 country
- Post-Marketing Clinical Study of High-Pressure Cutting BalloonRecruitingNCT07835178Not applicable1 country
- Molecular Imaging to Identify Predictors of Aortic Valve Disease ActivityNot yet recruitingNCT07819344
- Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Femoral Stenting (SKYWARD Trans-Femoral IDE [Investigational Device Exemption] Study)Not yet recruitingNCT07512128Not applicable1 country
- Comparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal LesionsRecruitingNCT06112171Not applicable1 country
- Intralesional Injection of STS in Treatment of CalcinosisRecruitingNCT06672822Phase 21 country
- Influence of Vessel Wall Calcification on Early Stent Strut HealingRecruitingNCT06631755Not applicable1 country
- TRAns-Femoral Access Intravascular Lithotripsy Comparison With PTA in TAVIRecruitingNCT058738421 country
- Imaging Quality and Potential Clinical Relevance of Phase Contrast Mammography In-vivo: a Single-center, Prospective StudyRecruitingNCT064896651 country
- The Added Value of Contrast Enhanced Mammography to Standard Mammography in Assessing the Extent of DCISNot yet recruitingNCT06217458Not applicable1 country
- Angioplasty With Shockwave IVL Catheter System in Femoropopliteal LesionsRecruitingNCT067138501 country
- The Safety and Performence of ShockPulse-10 in Patients with Coronary Artery CalcificationRecruitingNCT06711822Not applicable1 country
- Intravascular Lithotripsy for Acute Stent Under-expansion in Calcified Coronary LesionsNot yet recruitingNCT06669195Not applicable
- Calcification on CTCA of a CTO and PCI OutcomesRecruitingNCT064145511 country
- Safety and Efficacy of Topical Sodium Metabisulfite for the Treatment of Calcinosis in Patients With Systemic SclerosisNot yet recruitingNCT06155578Phase 1/21 country
- Calcinosis Reduction by Pyrophosphate in SSCNot yet recruitingNCT04966416Not applicable
- Serum and Cellular Biomarkers for Aortic Valve StenosisRecruitingNCT043121391 country
- Shockwave™ vs Surgical Endarterectomy for Calcified Severe Common Femoral Artery Stenosis: Comparison of Efficacy, Safety and Long-Term OutcomesActive, not recruitingNCT06829914Not applicable1 country
- Colchicine and Inflammation in Aortic StenosisActive, not recruitingNCT05162742Phase 31 country
- Prospective Observational Study for Breast Microcalcifications' Classification With Artificial Intelligence TechniquesActive, not recruitingNCT057674241 country
- SEAPORT 1: Study of INZ-701 in Adults With Hemodialysis-Dependent End-Stage Kidney DiseaseCompletedNCT06283589Phase 11 country
- Coronary Atherectomy System in Patients With Coronary Calcification (CORECT)CompletedNCT05447585Not applicable1 country
- Coronary Intravascular Lithotripsy System in Patients With Coronary Artery Calcification (VIGOUR)CompletedNCT05818098Not applicable1 country
- Biopsy of Calcifications Under Contrast Enhancement Guide (BoCCE)CompletedNCT04862429Not applicable1 country
- ClinicAL outComes of IntraVascular Lithotripsy Combined With Conventional Lesion Preparation in Patients With Moderate to Severe Coronary Artery CalcificationActive, not recruitingNCT07340294Not applicable1 country
- Lactobacillus Acidophilus and Postmenopausal WomenCompletedNCT05332626Not applicable1 country
- Evaluation of an Arterial Calcification Score as a Predictive Factor of Anastomotic Leakage in Right ColectomyCompletedNCT040029211 country
- Effects of Aerobic Versus Resistance Training on Bone Metabolism in Stage 3-4 Chronic Kidney DiseaseCompletedNCT07133256Not applicable1 country
- Ultrasound Imaging Technique in Detecting Breast Microcalcifications in Patients Undergoing Biopsy for a Breast AbnormalityCompletedNCT03031561Not applicable
- A Study to Assess Metabolic Bone Disease of Prematurity Using an Acoustic MethodCompletedNCT04752098Not applicable1 country
- Effect of Allopurinol on Markers of Mineral and Bone MetabolismCompletedNCT05601271Not applicable1 country
- CRUSTAL Study in ChinaActive, not recruitingNCT058281861 country
- Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult DermatomyositisCompletedNCT03267277Phase 2/31 country
- 64 Cu-DOTA-alendronate PET Imaging in Localizing and Characterizing Breast Calcifications in Participants Before Undergoing MastectomyCompletedNCT03542695Early Phase 11 country
- Metabolic Imaging in Carotid AtherosclerosisCompletedNCT016742571 country
- Calcinosis in a Single-Center Scleroderma PopulationCompletedNCT020621251 country
- Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial HypercholesterolemiaActive, not recruitingNCT048376381 country
- Influence of Calcium Pattern on Plaque Modification Achieved With Intracoronary LithotripsyCompletedNCT046989021 country
- Treatment of Calcific Tendinitis of the Rotator CuffCompletedNCT02419040Not applicable1 country
- Outcome of Endovascular Therapies in Chronic Femoropopliteal Occlusive Disease With Severe CalcificationStatus unknownNCT047163611 country
- Calcium Balance Studies in Children With CKD and on DialysisStatus unknownNCT032858541 country
- Rotablation vs Intravascular Lithotripsy in Calcified Coronary LesionsStatus unknownNCT04960319Not applicable
- Novel Imaging Approaches To Identify Unstable Coronary PlaquesCompletedNCT017492541 country
- Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic SclerosisCompletedNCT02663895Phase 21 country
- Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)CompletedNCT02966028Phase 23 countries
- Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE)CompletedNCT01525875Phase 21 country
- Reducing Aggression Among People With an Intellectual DisabilityCompletedNCT03212092Not applicable1 country
- A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve CalcificationCompletedNCT02481258Phase 21 country