An observational study in Breast Cancer, Breast Cyst and Microcalcification, sponsored by Johns Hopkins University. Enrolling by invitation at 1 site in United States. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-29.
Sponsored by Johns Hopkins University · Observational
This study aims to investigate recent developments in ultrasound signal processing to determine if these new techniques can enhance the visibility of important features of interest in breast ultrasound images. Ultrasound signals obtained from both standard ultrasound imaging and ultrasound imaging combined with light (also known as photoacoustic imaging) will be investigated.
14,825 studies on the registry are indexed under Breast Neoplasms; 3,319 are open to participants now.
This study's planned enrollment of 252 is above the median of 184 across 3,235 observational studies indexed under Breast Neoplasms.
Browse Breast Neoplasms studies →Johns Hopkins University is the lead sponsor of 1,815 studies on the registry; 315 are open to participants now.
Of its 208 completed or terminated interventional studies of FDA-regulated products, 144 (69%) have results posted.
Counted across the registry records on this site, refreshed daily.
Johns Hopkins Hospital
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
(when performing ultrasound imaging only)
(when performing ultrasound imaging with light, i.e., optoacoustic imaging)
Ultrasound imaging or ultrasound imaging with light (i.e., photoacoustic imaging)
Image quality
compare advanced beamforming and benchmark against a conventional beamforming technique by measuring and comparing standard image quality metrics
Time frame: baseline
Number of microcalcifications
Time frame: baseline
Binary visibility of microcalcifications
Clinicians (members of study team) will be shown images and record 'yes' if microcalcifications are present and 'no' if not.
Time frame: baseline
Subjective ratings
Clinicians (members of study team) will be shown images and asked to provide subjective ratings of the images
Time frame: baseline
Distinction of mass contents: solid vs. fluid
After examining the coherence measurements obtained from advanced beamforming techniques, the investigators will determine the ability of this quantitative information to distinguish between solid and fluid-filled masses
Time frame: baseline
Distinction of mass contents: benign vs. malignant
After examining the coherence measurements obtained from advanced beamforming techniques, the investigators will determine the ability of this quantitative information to distinguish between solid malignant masses vs. solid benign masses
Time frame: baseline
Number of true positives
The number of positive results that are correct
Time frame: baseline
Number of false positives
The number of positive results that are incorrect
Time frame: baseline
Number of true negatives
The number of negative results that are correct
Time frame: baseline
Number of false negatives
The number of negative results that are incorrect
Time frame: baseline
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
No contact was published for this record. The registry link below has the sponsor’s details.
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