Memorial Sloan Kettering Cancer Center: Brain Neoplasms trials

The registry lists 40 Brain Neoplasms studies with Memorial Sloan Kettering Cancer Center as lead sponsor. 5 are open to participants now and 10 have results posted.

Early Phase 1 2Phase 1 10Phase 2 9No phase 20(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study of Sotorasib in People With Brain TumorsRecruitingNCT06807619Phase 1
• Trastuzumab Deruxtecan (T-DXd) for People With Brain CancerRecruitingNCT06058988Phase 2
• Developing a New MRI Technique to Understand Changes in Brain Tumors After TreatmentRecruitingNCT05559853
• A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the BrainRecruitingNCT05419076Phase 2
• Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid TumorsRecruitingNCT00870129Not applicable
• Assessing 11C-Choline (11C-CH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade GliomasCompletedNCT02849171Not applicableResults posted
• A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor ProgressionCompletedNCT01604512Not applicableResults posted
• External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade AstrocytomasCompletedNCT01012609Phase 2Results posted
• Image-Guided Stereotactic Biopsy of High Grade GliomasCompletedNCT00979810Not applicableResults posted
• [18F] FACBC and [18F] FLT PET Imaging in Central Nervous System TumorsCompletedNCT00832598Not applicableResults posted
• Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant GliomaCompletedNCT00782756Phase 2Results posted
• Imaging Brain Tumors With FACBC and MethionineCompletedNCT00597246Not applicableResults posted
• Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant GliomasCompletedNCT00590954Phase 2Results posted
• Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain MetastasesCompletedNCT00587964Phase 2Results posted
• Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain MetastasesCompletedNCT00026494Phase 1/2Results posted
• A Study of 68Ga-PSMA-11 PET Scans in People With Brain TumorsActive, not recruitingNCT06209567Early Phase 1
• A Study of Cabozantinib and Nivolumab With Radiation Therapy for People With Renal Cell Carcinoma That Has Spread to the BrainActive, not recruitingNCT06132945Phase 1
• A Study of Avutometinib for People With Solid Tumor CancersActive, not recruitingNCT06104488Phase 1
• A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain TumorActive, not recruitingNCT05288439Not applicable
• Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II StudyActive, not recruitingNCT04690348Phase 2
• GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal MetastasesActive, not recruitingNCT04192981Phase 1
• PET and MRI Imaging of Brain Tumors Using [18F]PARPiCompletedNCT04173104Early Phase 1
• Communication Training for Caregivers In Advanced Care PlanningCompletedNCT04171895
• Evaluation of Preoperative Functional Magnetic Resonance Imaging (fMRI) in Patients With Brain TumorsActive, not recruitingNCT03604302Not applicable
• A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain TumorsActive, not recruitingNCT03465618Phase 1
• Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain TumorsActive, not recruitingNCT03220646Phase 2
• Understanding the Late Effects of Surviving a Pediatric Brain TumorActive, not recruitingNCT03208387
• Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor PrimaryActive, not recruitingNCT02429570Not applicable
• Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and CaregiversActive, not recruitingNCT02375841
• 18F-Fluorocholine (18F-FCho) to Distinguish Necrosis From Recurrence in Brain MetastasesCompletedNCT02037945Not applicable
• Assessment of Early Treatment Response by Diffusion and Perfusion MRI in Patients With Brain MetastasisCompletedNCT01974804
• Pilot Study of Optune (NovoTTF-100A) for Recurrent Atypical and Anaplastic MeningiomaActive, not recruitingNCT01892397Not applicable
• Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)CompletedNCT01724606Phase 1
• MRI and Diffusion Imaging of Eloquent Brain Areas to Optimize Brain Tumor Resection PlanningCompletedNCT01534104Not applicable
• Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant GliomaCompletedNCT01392209Phase 1
• A Feasibility Study of Image Guided Noninvasive Single Fraction Stereotactic Radiosurgery for the Treatment of Brain MetastasesCompletedNCT00610285
• Language Function in Patients With Brain TumorsCompletedNCT00599703
• Bevacizumab in the Radiation Treatment of Recurrent Malignant GliomaCompletedNCT00595322Not applicable
• Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor SurvivorsCompletedNCT00594633Phase 1
• Spectroscopy With Surface Coils and DecouplingCompletedNCT00581815Phase 1