Pinealoma clinical trials

The registry lists 66 studies for Pinealoma across more than 10 countries. 11 are recruiting or about to start. 11 of them are mainly about Pinealoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

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· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

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Status

Completed: 38
Recruiting: 10
Terminated: 7
Withdrawn: 4
Active, not recruiting: 3
Status unknown: 2

Phase

Phase 1: 32
Phase 2: 13
Early Phase 1: 3
Phase 3: 2

Where

United States: 53
Germany: 4
Canada: 4
Australia: 2
United Kingdom: 2
Switzerland: 2

Who runs them

National Cancer Institute (NCI) (11) · Wake Forest University Health Sciences (4) · Seattle Children's Hospital (3) · National Institutes of Health Clinical Center (CC) (3) · City of Hope Medical Center (2) · Case Comprehensive Cancer Center (2) · Children's National Research Institute (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1)

What is being tested here

Drugs under test in Pinealoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Fludarabine	1	0	1
Cyclophosphamide	1	0	1
Perillyl alcohol	1	0	1
Temozolomide	0	0	5
Sirolimus	0	0	2
Entinostat	0	0	2
Donepezil	0	1	2
Irinotecan	0	0	2
Temsirolimus	0	0	2
Carboplatin	0	0	2

Drug classes tested here Alkylating agents 1 open · mTOR inhibitors 4 · HDAC inhibitors 3

Coming up

0phase 3 studies under way

5studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 5

Dec 2026The Evolution of Neuroendoscopy Guided by Head-mounted Mixed Reality Technique Navigation System in Neurosurgery · Shanghai Zhongshan Hospital
Mar 2027Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms · Jazz Pharmaceuticals
May 2027Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors · Seattle Children's Hospital
Jun 2027A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors · Neonc Technologies, Inc.
Aug 2027GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults · Stanford University

Who these studies take

Of the 10 Pinealoma studies recruiting now, 2 (20%) set no upper age limit and 7 (70%) stop at 75 or younger. 9 (90%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (10%) take healthy volunteers.

Recruiting studies that take each age, of 10
Age	Women	Men
10	8 (80%)	8 (80%)
18	9 (90%)	9 (90%)
30	5 (50%)	5 (50%)
40	3 (30%)	3 (30%)
50	3 (30%)	3 (30%)
65	3 (30%)	3 (30%)
75	3 (30%)	3 (30%)
85	3 (30%)	3 (30%)

Across all 66 studies, recruiting or not: 45% stop at 75 or younger and 39% at 65; 47% take children; 0% are for women only and 2% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 50 of 66. Browse all 66 → or search them.