Pinealoma clinical trials
The registry lists 55 studies for Pinealoma across more than 10 countries. 12 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-15.
Status
- Completed
- 27
- Recruiting
- 11
- Terminated
- 9
- Withdrawn
- 3
- Active, not recruiting
- 2
- No longer available
- 1
Phase
- Phase 1
- 29
- Phase 2
- 10
- Early Phase 1
- 3
- Phase 3
- 1
Where
- United States
- 46
- Canada
- 6
- Germany
- 4
- Brazil
- 1
- Switzerland
- 1
- Australia
- 1
Who runs them
National Cancer Institute (NCI) (18) · Seattle Children's Hospital (3) · Massachusetts General Hospital (2) · Children's National Research Institute (2) · Pediatric Brain Tumor Consortium (2) · Barbara Ann Karmanos Cancer Institute (1) · Ashley Hill (1) · Neonc Technologies, Inc. (1)
Studies
Recruiting first, then most recently updated. Showing 50 of 55 — search for more.
- A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain TumorsRecruitingNCT06357377Phase 11 country
- GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young AdultsRecruitingNCT07087002Phase 11 country
- B7-H3.CD28Z.CART in CNS NeoplasmsRecruitingNCT07390539Phase 11 country
- Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post ConsolidationRecruitingNCT06942039Early Phase 11 country
- Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)RecruitingNCT06193759Phase 11 country
- A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.RecruitingNCT07017816Early Phase 11 country
- Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System TumorsRecruitingNCT04185038Phase 11 country
- Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsRecruitingNCT04541082Phase 11 country
- Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO ClassificationRecruitingNCT0525960512 countries
- International HIT-MED Registry (I-HIT-MED)RecruitingNCT024173241 country
- International PPB/DICER1 RegistryRecruitingNCT033821581 country
- The Evolution of Neuroendoscopy Guided by Head-mounted Mixed Reality Technique Navigation System in NeurosurgeryNot yet recruitingNCT06516471Not applicable
- Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS CancersTerminatedNCT03173950Phase 21 country
- Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas SystemCompletedNCT04743310Phase 21 country
- Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain TumorsTerminatedNCT059346302 countries
- Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS TumorsActive, not recruitingNCT02574728Phase 21 country
- EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS TumorsCompletedNCT03638167Phase 11 country
- HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS TumorsActive, not recruitingNCT03500991Phase 11 country
- Proton Beam Radiotherapy for Medulloblastoma and PineoblastomaCompletedNCT01063114Not applicable1 country
- 131I-omburtamab for the Treatment of Central Nervous System/Leptomeningeal Neoplasms in Children and Young AdultsNo longer availableNCT050643061 country
- Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid TumorCompletedNCT00638898Phase 11 country
- StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal CordWithdrawnNCT03990597Phase 11 country
- SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain TumorsCompletedNCT03434262Phase 11 country
- Stereotactic Radiosurgery in Treating Patients With Brain TumorsCompletedNCT00019578Phase 11 country
- Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid TumorsCompletedNCT02780804Phase 11 country
- Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid TumorsCompletedNCT02095132Phase 1/22 countries
- Role of Surgery in Management of Pineal Region Tumors in ChildrenStatus unknownNCT05781984
- Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer SyndromeCompletedNCT005659031 country
- Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous SystemCompletedNCT00867178Phase 11 country
- Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or PineoblastomaCompletedNCT00105560Not applicable1 country
- Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade PineoblastomaCompletedNCT02596828Phase 21 country
- Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal TumorsCompletedNCT01217437Phase 25 countries
- Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System TumorsTerminatedNCT02255461Phase 11 country
- Proton Beam Radiation Therapy in Treating Patients With Low Grade GliomasCompletedNCT01024907Phase 1/21 country
- Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With CancerTerminatedNCT01987596Phase 31 country
- Stem Cell Transplant for High Risk Central Nervous System (CNS) TumorsCompletedNCT00179803Phase 21 country
- A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research PurposesTerminatedNCT012519131 country
- Melatonin Replacement Therapy in Pinealectomized PatientsCompletedNCT03885258Early Phase 11 country
- Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade GliomaCompletedNCT01977677Phase 1/21 country
- Yoga Therapy in Treating Patients With Malignant Brain TumorsTerminatedNCT01234805Not applicable1 country
- A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid TumorsWithdrawnNCT01182883Phase 1
- Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain TumorsWithdrawnNCT02194452Not applicable1 country
- Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain MetastasesTerminatedNCT02967380Not applicable1 country
- AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS TumorsCompletedNCT00326664Phase 11 country
- Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance ImagingCompletedNCT018841941 country
- RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant GliomaCompletedNCT01119599Phase 11 country
- Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell LeukemiaTerminatedNCT01088763Phase 12 countries
- ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS TumorsCompletedNCT00946335Phase 11 country
- Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck CancerCompletedNCT00492089Phase 21 country
- Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS TumorsCompletedNCT00100880Phase 11 country