Pituitary Neoplasms clinical trials
The registry lists 200 studies for Pituitary Neoplasms across more than 10 countries. 51 are recruiting or about to start. 135 of them are mainly about Pituitary Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Prolactinoma: 217 studies, 57 open.
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Status
Who runs them
Novartis Pharmaceuticals (9) · Huashan Hospital (8) · St. Joseph's Hospital and Medical Center, Phoenix (6) · Peking Union Medical College Hospital (6) · National Institute of Neurological Disorders and Stroke (NINDS) (5) · Federico II University (5) · Columbia University (4) · Mayo Clinic (4)
What is being tested here
Drugs under test in Pituitary Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cabergoline | 1 | 2 | 6 |
| Gallium-68 | 1 | 0 | 1 |
| Panitumumab | 1 | 0 | 1 |
| IRDye800 | 1 | 0 | 1 |
| Deamino Arginine Vasopressin | 1 | 0 | 1 |
| Cefdinir | 1 | 0 | 1 |
| Pasireotide | 0 | 2 | 8 |
| Temozolomide | 0 | 1 | 3 |
| Dexmedetomidine | 0 | 0 | 3 |
| Sevoflurane | 0 | 0 | 2 |
Drug classes tested here Inhaled anesthetics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas · Phase 3 · St. Olavs Hospital
- Nov 2026To Assess the Impact of theERAS Consensus on Patients With Endoscopic Pituitary Tumor Surgery · Chang Gung Memorial Hospital
- Dec 2026Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas · Mayo Clinic
- Dec 2026NoSeal Trial: Comparing Sealants Versus No Sealant for Preventing CSF Leak After Endonasal Skull Base Surgery · Maria Sklodowska-Curie National Research Institute of Oncology
- Dec 2026Long-Term Longitudinal QoL in Patients Undergoing EEA · Ohio State University
- Dec 2026Long Term Outcome Study in Patients With Pituitary Disorders · University of Alberta
- Dec 2026Clinical Trial of an Anti-Fog Drainage Device for Endoscopic Endonasal Sellar Region Tumor Surgery · West China Hospital
- Dec 2026Individualized Physical Activity or Patients With Non Functioning Pituitary Adenoma · Vastra Gotaland Region
- Jan 2027Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors · Mayo Clinic
- Feb 2027A Study of Pasireotide in People With Prolactinoma · Memorial Sloan Kettering Cancer Center
Who these studies take
Of the 36 Pituitary Neoplasms studies recruiting now, 14 (39%) set no upper age limit and 10 (28%) stop at 75 or younger. 6 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (14%) | 5 (14%) |
| 18 | 33 (92%) | 33 (92%) |
| 30 | 36 (100%) | 36 (100%) |
| 40 | 36 (100%) | 36 (100%) |
| 50 | 36 (100%) | 36 (100%) |
| 65 | 36 (100%) | 36 (100%) |
| 75 | 32 (89%) | 32 (89%) |
| 85 | 22 (61%) | 22 (61%) |
Across all 200 studies, recruiting or not: 24% stop at 75 or younger and 10% at 65; 17% take children; 1% are for women only and 1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pituitary Neoplasms studies take
Of 46 interventional studies with no phase under Pituitary Neoplasms, half reached primary completion within 48 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 48 mo16–68 · 46 studies | — | — |
| Observational | 163 mo32–349 · 33 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 200. Browse all 200 → or search them.
- Evaluation and Treatment of Neurosurgical DisordersRecruitingNCT000605411 country
- 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.RecruitingNCT04081701Phase 41 country
- FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing DiseaseRecruitingNCT07460232Early Phase 11 country
- Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal SurgeryRecruitingNCT03678389Not applicable1 country
- International PPB/DICER1 RegistryRecruitingNCT033821581 country
- Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical ProceduresRecruitingNCT07493447Early Phase 11 country
- PRESTO: A Phase III Randomised Controlled Trial of Dose-escalated Proton Beam Therapy Versus Standard of Care Radiotherapy for Functioning Pituitary TumoursNot yet recruitingNCT07813351Phase 3
- To Assess the Impact of theERAS Consensus on Patients With Endoscopic Pituitary Tumor SurgeryRecruitingNCT062210201 country
- Perimetry Based on Eye-movements in Patients With (Supra)Sellar TumorsNot yet recruitingNCT062669491 country
- Temozolomide in Aggressive Pituitary Neuroendocrine Tumors: A Latin American Multicenter Retrospective Cohort (TMZ-LATAM)Not yet recruitingNCT07695844
- Clinical Trial of an Anti-Fog Drainage Device for Endoscopic Endonasal Sellar Region Tumor SurgeryRecruitingNCT07316101Not applicable1 country
- Direct Versus Video Laryngoscopy in Patients With AcromegalyNot yet recruitingNCT07659912
- Standardized Patient Education in Pituitary SurgeryNot yet recruitingNCT07618949Not applicable
- Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.Enrolling by invitationNCT07595666Not applicable1 country
- NET-TIME: Inflammatory Tumor Microenvironment in Pituitary NeoplasmRecruitingNCT075942621 country
- Study of 18FET PET in Functional Pituitary Adenomas With Indeterminate MRI FindingsNot yet recruitingNCT07360548Phase 21 country
- AI in Endoscopic Transsphenoidal SurgeryNot yet recruitingNCT07568366Early Phase 11 country
- DDAVP for Pituitary AdenomaRecruitingNCT04569591Not applicable1 country
- Pituitary Tumor Surveillance: Pathogenic CorrelationRecruitingNCT005990921 country
- Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary AdenomasRecruitingNCT07456878Phase 11 country
- A Study of Pasireotide in People With ProlactinomaRecruitingNCT06295952Phase 21 country
- Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI StudyRecruitingNCT04278118Not applicable1 country
- Evaluation of the CONVIVO SystemRecruitingNCT05139277Not applicable1 country
- Physical Attendance Versus Telephone or Video Follow-up in Patients With Non-functioning Pituitary Tumors.Enrolling by invitationNCT06297473Not applicable1 country
- Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary TumorsRecruitingNCT073353151 country
- Molecular Pituitary Imaging Using 18F-FET PETRecruitingNCT06584123Not applicable1 country
- Clinical Evaluation of [68Ga]Ga-NOTA-RF PET Imaging Targeting RFVT3 in Patients With Pituitary TumorsEnrolling by invitationNCT07254104Early Phase 11 country
- NoSeal Trial: Comparing Sealants Versus No Sealant for Preventing CSF Leak After Endonasal Skull Base SurgeryRecruitingNCT07216157Not applicable1 country
- Individualized Physical Activity or Patients With Non Functioning Pituitary AdenomaRecruitingNCT06163261Not applicable1 country
- Proton Versus Photon Radiotherapy in Adults With Primary Brain TumorsRecruitingNCT06831461Not applicable1 country
- Cabergoline in the Management of Nonfunctioning Pituitary AdenomaEnrolling by invitationNCT07034859Phase 41 country
- A Twenty-years' Experience in Pituitary Disease.RecruitingNCT069738241 country
- The Impact of Endoscopic Endonasal Skull Base Surgery on OlfactionRecruitingNCT068744263 countries
- Hydrocortisone in Hormone Replacement Therapy for Large Pituitary Neuroendocrine TumorsRecruitingNCT06679816Phase 41 country
- Osilodrostat Therapy and 11C-methionine PET to Improve Corticotroph Adenoma DetectionNot yet recruitingNCT06701838
- SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)RecruitingNCT052541971 country
- Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus RegionsRecruitingNCT067050361 country
- Application of Augmented Reality Neuronavigation in Transnasal Endoscopic Skull Base SurgeryRecruitingNCT06282224Not applicable1 country
- Surgical and Pharmacological Efficacy of Knosp Grade 0-2 ProlactinomaNot yet recruitingNCT06556186Not applicable
- Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsRecruitingNCT065235821 country
- Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid LeakageRecruitingNCT06472505Not applicable1 country
- Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical ModelsNot yet recruitingNCT06326853
- Neurocognition After Radiotherapy in CNS- and Skull-base TumorsRecruitingNCT05727605Not applicable1 country
- Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary SurgeryRecruitingNCT05659524Not applicable1 country
- Bed Rest on the Effect of CSF Leakage Repair After Transsphenoidal Pituitary SurgeryEnrolling by invitationNCT05682391Not applicable1 country
- Outcome Analysis of Endoscopic Resection of Pituitary AdenomasRecruitingNCT06156020Not applicable1 country
- Nasal Obstruction Compared by Rhinomanometry and Nasal Inspiratory Peak Flow After Endoscopic Nasal SurgeryRecruitingNCT05921396Not applicable1 country
- Predictive Value of Serum and Tissue Molecular Markers and Imaging Features in the Invasiveness and Prognosis of Pituitary Neuroendocrine TumorsRecruitingNCT060158021 country
- Application Research on Endoscopic Pseudocapsule-Based Resection for Pituitary AdenomasRecruitingNCT05466357Not applicable1 country
- China Pituitary Disease Registry (CAPASITY)RecruitingNCT047132931 country