Brain Death clinical trials
The registry lists 74 studies for Brain Death across more than 10 countries. 9 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 44
- Status unknown
- 10
- Terminated
- 8
- Recruiting
- 5
- Not yet recruiting
- 4
- Active, not recruiting
- 1
Phase
- Phase 2
- 6
- Phase 3
- 4
- Phase 4
- 3
- Phase 1
- 3
- Early Phase 1
- 1
Where
- France
- 15
- United States
- 13
- China
- 5
- Turkey
- 4
- Canada
- 4
- Czechia
- 3
Who runs them
University Hospital, Basel, Switzerland (3) · University Hospital, Aachen (2) · Washington University School of Medicine (2) · Institut d'Anesthesiologie des Alpes Maritimes (2) · Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged (2) · Brno University Hospital (2) · University Hospital, Limoges (2) · Chinese Academy of Medical Sciences (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 74 — search for more.
- Miniature In-line RespiratorNot yet recruitingNCT07768215Not applicable1 country
- Efficacy of High-Flow Humidified Oxygen (HFHO) in Apneic Oxygenation for Apnea Testing: A Comparison With Continuous Positive Airway Pressure (CPAP)Not yet recruitingNCT07640009Not applicable1 country
- Pupillometric Evaluation in Patients Declared Brain Dead - a Prospective Quality Control StudyRecruitingNCT062799751 country
- Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Computer Interface and Artificial IntelligenceNot yet recruitingNCT07477028
- CT-Angiography Versus Angiogram as Ancillary Tests in the Determination of Death by Neurologic CriteriaRecruitingNCT073414901 country
- Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter ImplantationRecruitingNCT06308952Phase 41 country
- ICU Management of Brain-Dead Donors Before Multi-Organ Procurement and Factors Associated With the Number of Organs RetrievedRecruitingNCT067685151 country
- Impact of Perioperative Organ Resuscitation of Brain-dead Deceased Organ Donor on Kidney Graft Function in the RecipientRecruitingNCT069077581 country
- Implementation of Apnoea Test for Patients With Suspected Brain DeathNot yet recruitingNCT06359119
- Therapeutic Hypothermia in "Expanded Criteria" Brain-dead Donors and Kidney-graft FunctionCompletedNCT03098706Not applicable1 country
- Cyclosporine A Pretreatment and Kidney Graft FunctionCompletedNCT02907554Phase 41 country
- The Anticipated Organ Donation ApproachCompletedNCT037658141 country
- Determining ICU Staffs Conceptions, Opinions, Views, Experiences and Reflection of Brain Death and Organ DonationCompletedNCT066400881 country
- ORI and ETCO₂ Relationship With Arterial Blood Gas During Apnea TestCompletedNCT069839901 country
- Prone vs Supine Position in Potential Organ Donors: Multicenter Clinical TrialCompletedNCT07251777Not applicable1 country
- Brain Death and Organ Donation in Tunisian Intensive Care UnitsCompletedNCT069486691 country
- Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY)Active, not recruitingNCT05148715Phase 21 country
- Etiology and Hemodynamic Instability in Brain DeathCompletedNCT065699921 country
- Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death DeterminationWithdrawnNCT03743805Early Phase 11 country
- Special Imaging Technique to Aid in the Diagnosis of Patients in Coma After Cardiac ArrestCompletedNCT02102945Not applicable1 country
- The Use of Liraglutide in Brain DeathCompletedNCT03672812Phase 31 country
- Electrical Impedance Tomography Measurements During Apnea Test in Patients With Suspected Brain DeathCompletedNCT04857242Not applicable1 country
- Orbital Artery Doppler Ultrasound in Brain DeathCompletedNCT06229782Not applicable1 country
- Intravenous Thyroxine for Heart-Eligible Organ DonorsCompletedNCT04415658Phase 31 country
- Research on the Brain Death Determination in ChinaCompletedNCT059034431 country
- Incidence of Complications of Brain DeathStatus unknownNCT044049721 country
- Methods of Confirmation of Brain DeathStatus unknownNCT047345741 country
- Does Venous pCO2 Increase by 20 mmHg or More During Apnea Challenge Test?CompletedNCT02503813Not applicable1 country
- Deceased Organ Donor Interventions to Protect Kidney Graft FunctionCompletedNCT02525510Not applicable1 country
- "LiverColor": Machine Learning in Liver PhotographsStatus unknownNCT05202886Not applicable1 country
- Safeguarding the Brain of Our Smallest Infants Phase IIICompletedNCT03770741Not applicable1 country
- Resting Energy Needs in Brain Dead Patients (reSting EneRgy nEeds iN brAin DEad Patients)CompletedNCT050701821 country
- Controlled Donors After Circulatory Death and Brain Death: a Multicenter Study of Transfusion, One-year Graft Survival and Mortality. Cohort Study,CompletedNCT049451351 country
- Evaluation of CTA on the Assessment of Brain DeathStatus unknownNCT049140391 country
- Brain Death Diagnosis at an Academic Tertiary Medical Care CenterCompletedNCT039849811 country
- Goal of Open Lung Ventilation in DonorsTerminatedNCT03439995Not applicable1 country
- HOPE for Human Extended Criteria and Donation After Brain Death Donor (ECD-DBD) Liver AllograftsCompletedNCT03124641Not applicable2 countries
- Online Noninvasive Assessment of Human Brain Death and Deep Coma by Near-infrared SpectroscopyStatus unknownNCT046232941 country
- Donation Network to Optimize Organ Recovery StudyCompletedNCT03179020Not applicable1 country
- Non-randomized, Open-labeled, Interventional, Single Group, Proof of Concept Study With Multi-modality Approach in Cases of Brain Death Due to Traumatic Brain Injury Having Diffuse Axonal InjuryCompletedNCT02742857Phase 11 country
- Thyroid and Adrenocortical Hormone Replacement in Organ DonorsCompletedNCT04528797Not applicable
- Naloxone for Optimizing Hypoxemia Of Lung DonorsCompletedNCT02581111Phase 2/31 country
- Hypothermic Oxygenated Machine Perfusion of Extended Criteria Kidney Allografts From Brain Death DonorsCompletedNCT03378817Not applicable1 country
- Understanding Family RefusalCompletedNCT04303624
- Expanding Pancreas Donor Pool by Evaluation of Unallocated Organs After Brain Death - The EXPLORE StudyStatus unknownNCT041272661 country
- Evaluation of Liver Grafts With FibroScan® Before Organ Retrieval in Patients With Brain DeathCompletedNCT02460250Not applicable1 country
- Neurophysiological Examination in Patients With Brain DeathCompletedNCT032628961 country
- Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety StudyCompletedNCT02635347Not applicable1 country
- Computed Tomography Angiography Accuracy in Brain Death DiagnosisCompletedNCT020454071 country
- Uterine Allotransplantations Using Uterine Grafts From Brain-dead Female DonorsSuspendedNCT02637674Not applicable1 country