Blindness clinical trials
The registry lists 144 studies for Blindness across more than 10 countries. 33 are recruiting or about to start. 76 of them are mainly about Blindness (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30. Counting its 2 narrower conditions too, such as Hemianopsia: 233 studies, 67 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Adverum Biotechnologies, Inc. (8) · US Department of Veterans Affairs (6) · Oregon Health and Science University (5) · Vanda Pharmaceuticals (5) · National Eye Institute (NEI) (5) · National Institute of Neurological Disorders and Stroke (NINDS) (4) · Istituto Italiano di Tecnologia (3) · Massachusetts Eye and Ear Infirmary (3)
What is being tested here
Drugs under test in Blindness studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Sepofarsen | 1 | 3 | 4 |
| Melatonin | 0 | 0 | 6 |
| Tasimelteon | 0 | 4 | 4 |
| Aflibercept | 0 | 2 | 2 |
| Rituximab | 0 | 0 | 1 |
| Azd-4017 | 0 | 0 | 1 |
| Tesidolumab | 0 | 0 | 1 |
| Aspirin | 0 | 1 | 1 |
| Sildenafil | 0 | 0 | 1 |
| Ketorolac Tromethamine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 9, phase 3 first
- Dec 2026Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration · Phase 3 · Adverum Biotechnologies, Inc.
- Nov 2027Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION) · Phase 3 · Laboratoires Thea
- Nov 2027Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
- Dec 2026Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema · Carmen Clapp
- Dec 2026Feasibility of Stimulating the Visual Cortex in Blind · University of California, Los Angeles
- Jun 2027A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People With Blindness · Illinois Institute of Technology
- Jul 2027Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss · The Chicago Lighthouse
- Jul 2027Stem Cell Ophthalmology Treatment Study II · MD Stem Cells
- Aug 2027AI-Powered Artificial Vision for Visual Prostheses · University of California, Santa Barbara
Who these studies take
Of the 20 Blindness studies recruiting now, 13 (65%) set no upper age limit and 4 (20%) stop at 75 or younger. 5 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (30%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (20%) | 4 (20%) |
| 18 | 14 (70%) | 14 (70%) |
| 30 | 15 (75%) | 15 (75%) |
| 40 | 16 (80%) | 16 (80%) |
| 50 | 18 (90%) | 18 (90%) |
| 65 | 18 (90%) | 18 (90%) |
| 75 | 16 (80%) | 16 (80%) |
| 85 | 14 (70%) | 14 (70%) |
Across all 144 studies, recruiting or not: 29% stop at 75 or younger and 18% at 65; 36% take children; 2% are for women only and 1% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Blindness studies take
Of 36 interventional studies with no phase under Blindness, half reached primary completion within 57 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 57 mo19–… · 36 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 144. Browse all 144 → or search them.
- Multisensory Rehabilitation of Vision Loss After Cortical DamageNot yet recruitingNCT07659691Not applicable1 country
- Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)RecruitingNCT06891443Phase 310 countries
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)RecruitingNCT07482176Phase 31 country
- Effect of Visual Retraining After StrokeRecruitingNCT06121219Not applicable1 country
- Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General PracticeRecruitingNCT07015034Not applicable1 country
- AI-Powered Artificial Vision for Visual ProsthesesEnrolling by invitationNCT06117332Not applicable2 countries
- Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular DegenerationRecruitingNCT07630649Phase 21 country
- Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable3 countries
- A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People With BlindnessRecruitingNCT04634383Not applicable1 country
- Study Protocol: The Jerte Valley as an Inclusive Outdoor Classroom. Smart and Active Tourism.Not yet recruitingNCT07609459Not applicable
- Development of a Cortical Visual Neuroprosthesis for the BlindRecruitingNCT02983370Not applicable1 country
- Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic QualityEnrolling by invitationNCT07529041Not applicable1 country
- Evaluation of the Efficacy and Safety of Aspheric Keratoprosthesis in the Treatment of Patients With Corneal Blindness: A Clinical StudyNot yet recruitingNCT07526389Not applicable
- Sensory Substitution and Brain Plasticity Following Vision LossNot yet recruitingNCT07450677Not applicable1 country
- Multicenter Study of Transcranial Magnetic Stimulation on Vision RestorationNot yet recruitingNCT07425717Not applicable1 country
- Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular EdemaRecruitingNCT03161652Phase 21 country
- Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision LossRecruitingNCT07073521Not applicable1 country
- Validation of Texture Changing Coatings for Use in At-Home Rapid TestsNot yet recruitingNCT06539728Not applicable1 country
- Effect of Presbyopia Correction on Livelihood and Repayment Among Solar Customers in Western Region, KenyaNot yet recruitingNCT06774183Not applicable
- The Impact of the Years of Blindness on Sleep and Dreaming Processes and the Relationships With Spatial AbilitiesEnrolling by invitationNCT066318071 country
- Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye DiseasesRecruitingNCT060704671 country
- A Pilot Study Comparing Performance of Blind Participants on 12 Tasks, With and Without the ARIA DeviceRecruitingNCT06477809Not applicable1 country
- Visual Involvement in Giant Cell ArteritisRecruitingNCT065007281 country
- Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial KeratitisRecruitingNCT06451172Early Phase 11 country
- MySpace: the Role of Vision in Representing SpaceEnrolling by invitationNCT06364605Not applicable1 country
- iReach: a Rehabilitative Medical DeviceNot yet recruitingNCT06334614Not applicable
- Testing Tactile Aids With Blind SubjectsRecruitingNCT06237829Not applicable1 country
- Sleep Profile of Patients With Septo-optic DysplasiaRecruitingNCT062621521 country
- The Effect of Education Based on Health Belief Model on Smoking Behaviors of Visually Impaired IndividualsRecruitingNCT05910203Not applicable1 country
- Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual ImpairmentRecruitingNCT05377853Not applicable1 country
- Vision Improvement for Legally Blind Dry AMD PatientsNot yet recruitingNCT04875234
- Shanghai Eye Study for AdultsRecruitingNCT03455478Not applicable1 country
- Patient Registry of Blind Subjects With Sleep-related ProblemsRecruitingNCT011955581 country
- Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)Active, not recruitingNCT056078102 countries
- Aflibercept After Ranibizumab in Exudative Age-related Macular DegenerationCompletedNCT02157077Phase 31 country
- Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA]Active, not recruitingNCT05536973Phase 23 countries
- Genetic Analyses of Nonsyndromic and Syndromic Deafness in PakistanCompletedNCT003418741 country
- Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT)Active, not recruitingNCT04271709Not applicable1 country
- Oral Proprioceptive Sensitivity and Upper Limb Kinesthetic Acuity: A Pilot StudyCompletedNCT078543141 country
- Wearable Echolocation Aids Using Parametric SoundCompletedNCT07218991Not applicable1 country
- Audio-Described Menopause Education Program in Visually Impaired WomenCompletedNCT07771946Not applicable1 country
- Prevalence of Glaucoma and Normative Data of Ocular Biometry in Elderly Population in BangkokCompletedNCT077632881 country
- VISIODOL: Validation of the VISIODOL® ScaleTerminatedNCT03968991Not applicable1 country
- Simulated Walking With Multiplexing Prism for Field Expansion in Monocular VisionWithdrawnNCT06024668Not applicable1 country
- Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBOCompletedNCT03841734Phase 31 country
- The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 DiabetesActive, not recruitingNCT01047735Not applicable1 country
- Eye Health Intervention Study in Upper ManhattanWithdrawnNCT06112431Not applicable1 country
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular DegenerationActive, not recruitingNCT06856577Phase 31 country
- Clinical Trial Evaluating Rituximab in Ocular Cicatricial PemphigoidCompletedNCT00584935Phase 1/21 country
- Multisensory Rehabilitation of HemianopiaCompletedNCT04963075Not applicable1 country