An interventional study of Multiplexing Prism in One Eye Blindness, Blind Left Eye and Blind Right Eye, sponsored by Massachusetts Eye and Ear Infirmary. Withdrawn at 1 site in United States. Open to participants aged 16 Years and older. Per ClinicalTrials.gov, last updated 2026-07-09.
Sponsored by Massachusetts Eye and Ear Infirmary · Not applicable, Interventional, and Basic science
The investigators are developing an assistive device, known as multiplexing prism that expands the field of view for individuals with acquired monocular vision (loss of an eye). The investigators will test the efficacy of the prism in improving the detection of colliding pedestrians during a simulated walking task.
144 studies on the registry are indexed under Blindness; 33 are open to participants now.
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Participants will perform a simulated walking task in which surrounding pedestrians will walk towards and make a collision. Participants will respond by pressing buttons to indicate the direction of the colliding pedestrians. Participants will perform the task with and without the multiplexing prism in random orders.
Device: Multiplexing Prism
Multiplexing prism is designed for spatial vision multiplexing. It allows partial light transmission through the prism allow the observer to simultaneously see the physical world through the prism and see the "shifted view" from the non-seeing side. It is developed to expand the field of view of individuals with just one eye.
Mean response time to detect colliding pedestrian
The investigators will compare the mean response time to detect colliding pedestrians coming from the nasal (same side as the blind eye) and temporal (same side as the seeing eye) visual field with and without multiplexing prism. The comparison will be made between these four: Nasal without prism, Temporal without prism, Nasal with prism, and Temporal with prism.
Time frame: Approximately 3 sessions, up to 3 hours for each session, any time within 4 month period
Pedestrian Detection Rate
The investigators will measure the rate of correct detection rate of colliding pedestrians in the nasal (same side as the blind eye) and temporal (same side as the seeing eye) with and without multiplexing prism. Comparisons will be made for these: nasal without prism, temporal without prism, nasal with prism,and temporal with prism.
Time frame: Approximately 3 sessions, up to 3 hours for each session, any time within 4 month period
Plan to share: No
Ran from Aug 2024 to primary completion in Dec 2024, 4 months.
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This study is withdrawn, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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