An observational study in Biofilms, Arterial Catheterization, Peripheral and Bacteremia, sponsored by Centre Hospitalier William Morey - Chalon sur Saône. Recruiting at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-03-18.
Sponsored by Centre Hospitalier William Morey - Chalon sur Saône · Observational
29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality.
It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias.
The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.
297 studies on the registry are indexed under Bacteremia; 51 are open to participants now.
This study's planned enrollment of 60 is below the median of 300 across 125 observational studies indexed under Bacteremia.
Browse Bacteremia studies →Centre Hospitalier William Morey - Chalon sur Saône is the lead sponsor of 7 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patient over 18 years of age with artherial catheter more than 2 calendar days
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Critically ill patient \> 18 years of age with artherial catheter for \>2 calendar days in ICU
Other: OCT-BIO-KTA cohort
Dynamic full-field optical coherence tomography (D-FF-OCT) analysis of arterial catheter sections before microbiological analysis of catheter biofilm
Biofilm structure type (ribbon-shaped or mushroom-shaped), measured with D-FF-OCT
Provide a better understanding of the relation between structural and microbiological characterization of artherial catheter biofilm in ICU patients using D-FF-OCT
Time frame: Outcome measure is assessed 2 days following catheter removal
Bacterial or fungal indentification
Identification and enumeration of species - whether bacterial or fungal - by mass spectrometry from culture in agar medium of biofilm samples
Time frame: Outcome measure is assessed 2 days following catheter removal
Biofilm thickness, measured with D-FF-OCT
Provide a better understanding of the relation between thickness and microbiological characterization of artherial catheter biofilm in ICU patients using D-FF-OCT
Time frame: Outcome measure is assessed 2 days following catheter removal
Biofilm dynamic signal distribution, measured with D-FF-OCT
Provide a better understanding of the relation between dynamic signal distribution and microbiological characterization of artherial catheter biofilm in ICU patients using D-FF-OCT
Time frame: Outcome measure is assessed 2 days following catheter removal
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Centre Hospitalier William Morey - Chalon sur Saône