An observational study in Pneumonia, Meningitis and Sepsis, sponsored by American University of Beirut Medical Center. Recruiting at 1 site in Lebanon. Open to participants aged 1 Day and older. Per ClinicalTrials.gov, last updated 2023-02-03.
Sponsored by American University of Beirut Medical Center · Observational
Streptococcus pneumoniae (pneumococcus) is a bacterium that causes severe infections in children and adults such as meningitis, pneumonia, and blood stream infection. There are many types of these bacteria defined by the type of sugar coat that they have. These are classified as serotypes. There are common serotypes that cause severe disease and are preventable by vaccination of children. Other less common types are more difficult to prevent. The investigators aim to determine the serotypes that cause invasive pneumococcal disease in Lebanon and to study their sensitivity to different antibiotics. The investigators will collect bacterial isolates from different hospitals in Lebanon isolated from the blood or spinal fluid of patients with invasive pneumococcal disease. This information will help the investigators determine the usefulness of available pneumococcal vaccines in preventing these infections. The data will be distributed to all primary care physicians treating children in Lebanon and will be shared with the Ministry of Health.
patients with invasive pneumococcal disease with positive culture of S. pneumoniae from a normally sterile site (blood, CSF, etc.)
Samples included in the study are those that are:
Acceptable samples include:
Exclusion Criteria:
Serotype prevalence of S. pneumoniae in invasive pneumococcal disease
Time frame: yearly
Determine the antibiotic sensitivity of S. pneumoniae and the association with specific serotypes
Time frame: yearly
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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American University of Beirut Medical Center