Aortic Diseases clinical trials
The registry lists 108 studies for Aortic Diseases across more than 10 countries. 43 are recruiting or about to start. 33 of them are mainly about Aortic Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 11 narrower conditions too, such as Aortic Aneurysm, Abdominal: 1,109 studies, 313 open.
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Who runs them
Fondazione Policlinico Universitario Agostino Gemelli IRCCS (6) · Xijing Hospital (3) · Helse Nord-Trøndelag HF (2) · Medtronic Cardiovascular (2) · Vascutek Ltd. (2) · Barts & The London NHS Trust (2) · Cook Research Incorporated (2) · Braile Biomedica Ind. Com. e Repr. Ltda. (2)
What is being tested here
Drugs under test in Aortic Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Liposomal Bupivacaine | 1 | 0 | 1 |
| Bupivacaine | 1 | 0 | 1 |
| Propofol | 0 | 0 | 2 |
| Sevoflurane | 0 | 0 | 2 |
| Aminocaproic Acid | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10
- Dec 2026Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR · EnCompass Technologies, Inc.
- Dec 2026Soft Foam Dressings for Pressure Injury Prevention of Cardiac Surgery · Shih,Wen-Chi
- Mar 2027Safety and Efficacy of XJ-Procedure in Patients With Acute Type A Aortic Dissection Surgery · First Affiliated Hospital Xi'an Jiaotong University
- Mar 2027Digital Twin and Ml-basEd MOdel of TEVAR Interventions · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- Jun 2027Identification of Genetic Causes of Calcific Aortic Valve Disease · Beth Israel Deaconess Medical Center
- Jun 2027Phenotyping Heterogeneity and Regionality of the Aorta · Heinrich-Heine University, Duesseldorf
- Jul 2027Intervascular Post-Market Clinical Follow-Up (PMCF) Registry · Intervascular
- Jul 2027Assess Abdominal Aortic Diameter in Females · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- Aug 2027Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac Access · EndoCore Lab s.r.l.
- Nov 2027A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta · Vascutek Ltd.
Who these studies take
Of the 36 Aortic Diseases studies recruiting now, 28 (78%) set no upper age limit and 2 (6%) stop at 75 or younger. 2 (6%) take children under 18. 1 (3%) are for women only and 0 (0%) for men only; 6 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (6%) | 2 (6%) |
| 18 | 32 (89%) | 32 (89%) |
| 30 | 35 (97%) | 35 (97%) |
| 40 | 35 (97%) | 35 (97%) |
| 50 | 36 (100%) | 35 (97%) |
| 65 | 36 (100%) | 35 (97%) |
| 75 | 34 (94%) | 33 (92%) |
| 85 | 32 (89%) | 31 (86%) |
Across all 108 studies, recruiting or not: 4% stop at 75 or younger and 1% at 65; 14% take children; 1% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Aortic Diseases studies take
Of 33 observational studies under Aortic Diseases, half reached primary completion within 98 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 28 mo12–107 · 21 studies | — | — |
| Observational | 98 mo43–203 · 33 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 50 of 108. Browse all 108 → or search them.
- Trial of the F2 Filter and Delivery System for Embolic Protection During TAVRRecruitingNCT06689839Not applicable2 countries
- Digital Twin and Ml-basEd MOdel of TEVAR InterventionsRecruitingNCT076408281 country
- Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world PracticeRecruitingNCT070686331 country
- Intervascular Post-Market Clinical Follow-Up (PMCF) RegistryRecruitingNCT073229134 countries
- Multimodal Physiologic State Intelligence StudyEnrolling by invitationNCT078141181 country
- Cerebral Protection in Aortic Arch SurgeryRecruitingNCT049662471 country
- Selective Antegrade Cerebral Perfusion and Perioperative Optic Nerve Sheath Diameter in Ascending Aortic SurgeryNot yet recruitingNCT07800806Not applicable1 country
- PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular PatchesRecruitingNCT045455026 countries
- Prospective Multicenter Study Evaluating Myval TAVR Safety and Effectiveness in High-risk Severe ARNot yet recruitingNCT07751965Not applicable
- Longitudinal Validation of CIRC TechnologiesRecruitingNCT070817111 country
- A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the AortaRecruitingNCT07078383Not applicable5 countries
- Accessing the Clarity and Acceptability of Recruitment Materials for a Study on Thoracic Aortic Disease SurveillanceRecruitingNCT075741511 country
- Construction of a Prospective Cohort Database for the Perioperative Period of Cardiac SurgeryRecruitingNCT076623171 country
- Impact of Aortic Diseases on Quality of Life and Work AbilityRecruitingNCT074791861 country
- Outcomes of Aortic Dissection RepairEnrolling by invitationNCT059270901 country
- Soft Foam Dressings for Pressure Injury Prevention of Cardiac SurgeryNot yet recruitingNCT07379294Not applicable
- Development of CIRC TechnologiesRecruitingNCT056542721 country
- INFLATE Study: Investigation of the Safety and Performance of a Novel PTV Balloon in Patients Undergoing TAVI for Severe Aortic StenosisRecruitingNCT06816485Not applicable1 country
- Prospective Aortic Biobank of POP-STAREnrolling by invitationNCT042694471 country
- Assess Abdominal Aortic Diameter in FemalesRecruitingNCT074879611 country
- Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac AccessRecruitingNCT058806411 country
- Cardiac Remodelling Following Endovascular Repair of the AortaRecruitingNCT074154471 country
- Duke Customized Aortic Aneurysm Repair With Endovascular Stent-grafts - Duke CARES TrialRecruitingNCT07064460Not applicable1 country
- Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic DiseaseRecruitingNCT040059766 countries
- Comparison of the Diagnosis Time of VET and SCL in Patients With Intraoperative CoagulopathyNot yet recruitingNCT066379431 country
- Comparing Hypothermic Temperatures During Hemiarch SurgeryRecruitingNCT02860364Not applicable2 countries
- Liposomal Bupivacaine/Bupivacaine in Rectus Sheath Blocks Versus Ropivacaine in Rectus Sheath Blocks And CathetersRecruitingNCT05972018Phase 41 country
- Management of Aorto-iliac Infection With BioIntegral Surgical No-React® Bovine Pericardial XenograftsRecruitingNCT057776811 country
- Concordance of Three Imaging Methods by Dynamic CT, Contrast Ultrasound and CT Angiography in the Characterization of Endoleaks in Patients With an Aortic EndoprosthesisRecruitingNCT06318780Not applicable1 country
- Active Thoracic Compromised Distal LANding in TEvarRecruitingNCT068829671 country
- Mid- and Long-term Outcomes of Custom-made Aortic DevicesRecruitingNCT057774601 country
- International Multicenter Mycotic Aneurysm Aorto-iliac StudyRecruitingNCT057774471 country
- Post-market Clinical Trial of the Dominus® Stent-GraftRecruitingNCT062705371 country
- Gastrointestinal Dysfunction in Aortic Surgery PatientsRecruitingNCT065141701 country
- Asan Aorta and Peripheral RegistryRecruitingNCT060226531 country
- Safety and Efficacy of XJ-Procedure in Patients With Acute Type A Aortic Dissection SurgeryRecruitingNCT06199401Not applicable1 country
- AOrtic Surgery: Systemic Inflammatory Response Versus SepsisRecruitingNCT060287891 country
- Standardized Physician-modified Fenestrated Endograft RegistryRecruitingNCT063582481 country
- Phenotyping Heterogeneity and Regionality of the AortaRecruitingNCT056035201 country
- Percutaneous Endovascular Arch Repair Trial (PEART) StudyRecruitingNCT05872282Not applicable1 country
- Registry of Multicenter Brain-Heart Comorbidity in ChinaRecruitingNCT059617481 country
- ENDOBARC-S Study: "Endovascular Branched Stent-grafts for Aortic ARCh Pathologies in Spain"RecruitingNCT053097071 country
- CILCA Arch Registry: Management and Outcomes of Open and Endovascular RepairRecruitingNCT049956401 country
- Prehabilitation for Patients Undergoing Elective Cardiac SurgeryCompletedNCT07704086Not applicable1 country
- Identification of Genetic Causes of Calcific Aortic Valve DiseaseActive, not recruitingNCT041496001 country
- Effective Myocardial Protection Time of Del Nido Cardioplegia in Adult Cardiac SurgeryCompletedNCT072494241 country
- Post-market Registry of the AMDS for the Treatment of Acute DeBakey Type I DissectionActive, not recruitingNCT038940331 country
- PENG Block forTranscatheter Aortic Valve ImplantationCompletedNCT05904912Not applicable1 country
- Antibiotic Prophylaxis for TEVARTerminatedNCT054057901 country
- Aortic Dissection fAlse enlarGement radIomics predictiOnActive, not recruitingNCT071178251 country