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Active, not recruitingNCT07117825ADAGIOUpdated Aug 12, 2025

Aortic Dissection fAlse enlarGement radIomics predictiOn

An observational study in Dissection, Aortic Diseases and Aortic Dissection, sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Active, not recruiting at 1 site in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-08-12.

Primary conditionAortic DissectionRegistry: Aortic DiseasesReclassifiedWhy we changed it
Registry
Aortic Diseases — the first condition term the registry derived for this study.
ClinicalTrials.gg
Aortic Dissection
Why
  1. The study's listed conditions name Aortic Dissection, a narrower term within Aortic Diseases.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Observational

From the registry’s dates

  • Primary completion was expected by Jan 2026, 10 months ago, but the record still lists the study as active, not recruiting.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
500
Ages
18 Years and older
Sex
All
01

Study summary

The objective of this study is to find, in acute phase of aortic dissection, CT scans characteristics through radiomics features, that can help us to predict a significant growth of dissected descending aorta or a false lumen enlargement in order to treat the patient promptly.

02

Conditions studied

  • Dissection
  • Aortic Diseases
  • Aortic Dissection

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03

In context

Aortic Dissection Reclassified

205 studies on the registry are indexed under Aortic Dissection; 73 are open to participants now.

This study's planned enrollment of 500 is above the median of 230 across 115 observational studies indexed under Aortic Dissection.

Browse Aortic Dissection studies →

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS is the lead sponsor of 952 studies on the registry; 541 are open to participants now.

Browse Fondazione Policlinico Universitario Agostino Gemelli IRCCS studies →

Compared within Aortic Dissection, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Aortic Diseases. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Patients with type A or type B acute aortic dissection, treated either with medical therapy or with endovascular/open surgery in the study period and who underwent subsequent radiological follow-up.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with previous acute aortic (type A or B) dissection, undergoing medical or surgical therapy and in clinical-radiological follow-up.

Exclusion criteria

Exclusion Criteria:

  • Patients with no appropriate radiological follow up;
  • Patients who died in the acute phase of aortic type A or B dissection.
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
500 participants (estimated)
Patient registry
No

Interventions

  • OtherAORTIC DISSECTION CT SCAN ANALYSIS

    Patients with type A or type B acute aortic dissection, treated either with medical therapy or with endovascular/open surgery in the study period and who underwent subsequent radiological follow-up.

06

What researchers measure

Primary outcomes

  1. Predict the false lumen enlargement (>5.5 mm aortic diameter growth at CT follow-up control) through radiomics analysis applied on CT scans.

    Time frame: 24 MONTHS

07

Study locations

1 site
  • Giovanni Tinelli
    Roma, Italy
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07117825
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Responsible party
TINELLI GIOVANNI (Prof, Fondazione Policlinico Universitario Agostino Gemelli IRCCS) — Principal investigator
First posted
Aug 12, 2025
Start date
Sep 30, 2024
Primary completion
Jan 1, 2026 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
Aug 12, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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