Children's Oncology Group: Osteosarcoma trials

The registry lists 24 Osteosarcoma studies with Children's Oncology Group as lead sponsor. 3 are open to participants now and 8 have results posted.

Phase 1 3Phase 2 7Phase 3 5No phase 11(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With OsteosarcomaRecruitingNCT05235165Phase 3
• Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsRecruitingNCT04851119Phase 1/2
• Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer TreatmentRecruitingNCT01790152
• Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid TumorsCompletedNCT03320330Phase 1/2Results posted
• Denosumab in Treating Patients With Recurrent or Refractory OsteosarcomaCompletedNCT02470091Phase 2Results posted
• Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or LeukemiaCompletedNCT01154816Phase 2Results posted
• Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic OsteosarcomaCompletedNCT00742924Phase 1Results posted
• Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyCompletedNCT00716976Phase 3Results posted
• Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue SarcomaCompletedNCT00346164Phase 3Results posted
• Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With OsteosarcomaCompletedNCT00134030Phase 3Results posted
• Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of OsteosarcomaCompletedNCT00066365Phase 2Results posted
• Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma SurvivorsCompletedNCT03206450
• Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid TumorsWithdrawnNCT02011126Phase 2
• Genetic Biomarkers in Tissue Samples From Patients With OsteosarcomaCompletedNCT01807143
• Biomarker Expression in Tissue Samples From Patients With Bone SarcomasCompletedNCT01807052
• Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With OsteosarcomaCompletedNCT01374672
• DNA Biomarkers in Tissue Samples From Patients With OsteosarcomaCompletedNCT01190943
• DNA Biomarkers in Samples From Patients With Osteosarcoma and Healthy VolunteersCompletedNCT01139983
• Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic OsteosarcomaCompletedNCT01062438
• Study of Blood Samples From Patients With OsteosarcomaCompletedNCT00954473
• Collecting and Storing Samples of Blood and Tumor Tissue From Patients With OsteosarcomaCompletedNCT00899275
• Collecting and Storing Tissue From Young Patients With CancerCompletedNCT00898755
• Irinotecan in Treating Children With Refractory Solid TumorsCompletedNCT00004078Phase 2
• Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic OsteosarcomaCompletedNCT00003937Phase 3