Children's Oncology Group: Leukemia trials

The registry lists 140 Leukemia studies with Children's Oncology Group as lead sponsor. 2 are open to participants now and 28 have results posted.

Phase 1 15Phase 2 22Phase 3 26No phase 82(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer TreatmentRecruitingNCT01790152
• Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group StudiesRecruitingNCT00736749
• Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL)CompletedNCT03792256Phase 1Results posted
• Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell TransplantActive, not recruitingNCT03057054Phase 3Results posted
• Liposome-encapsulated Daunorubicin-Cytarabine, Fludarabine Phosphate, Cytarabine, and Filgrastim in Treating Younger Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT02642965Phase 1/2Results posted
• Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic LeukemiaCompletedNCT01824693Phase 2Results posted
• Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell TransplantCompletedNCT01817075Phase 3Results posted
• Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell TransplantationCompletedNCT01371656Phase 3Results posted
• Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid LeukemiaCompletedNCT01307579Phase 3Results posted
• Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell TransplantCompletedNCT01305200Phase 3Results posted
• Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or LeukemiaCompletedNCT01154816Phase 2Results posted
• Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic LeukemiaCompletedNCT00866918Phase 3Results posted
• Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (Closed to Accrual 4-22-2011)CompletedNCT00866307Phase 1Results posted
• Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic LeukemiaCompletedNCT00671034Phase 3Results posted
• Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT00557193Phase 3Results posted
• Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous LeukemiaCompletedNCT00553202Phase 2Results posted
• Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic LeukemiaCompletedNCT00537030Not applicableResults posted
• Lestaurtinib, Cytarabine, and Idarubicin in Treating Younger Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00469859Phase 1/2Results posted
• Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other DiseasesCompletedNCT00450450Phase 3Results posted
• Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete RemissionCompletedNCT00382109Phase 3Results posted
• Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic LeukemiaCompletedNCT00381680Phase 3Results posted
• Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic LeukemiaCompletedNCT00372619Phase 1/2Results posted
• Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT00372593Phase 3Results posted
• Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic SyndromesCompletedNCT00369317Phase 3Results posted
• Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell TransplantCompletedNCT00309907Phase 2Results posted
• Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT00103285Phase 3Results posted
• Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)CompletedNCT00098839Phase 1/2Results posted
• Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or TestesCompletedNCT00096135Not applicableResults posted
• Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic LeukemiaCompletedNCT00075725Phase 3Results posted
• Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or LymphomaCompletedNCT00057811Phase 2Results posted
• A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to TreatWithdrawnNCT05320380Phase 1/2
• Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic LeukemiaCompletedNCT03204916
• Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric OncologyCompletedNCT02847130
• Studying Biomarkers in Samples From Younger Patients With Acute Myeloid LeukemiaCompletedNCT01642121
• Studying Genes in Samples From Younger Patients With Acute Megakaryoblastic LeukemiaCompletedNCT01642069
• Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 TrialCompletedNCT01629745
• Studying RNA in Samples From Younger Patients With T-Cell Acute Lymphoblastic LeukemiaCompletedNCT01626183
• Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic LeukemiaCompletedNCT01625143
• Studying Samples From Patients With T-Cell Acute Lymphoblastic LeukemiaCompletedNCT01581528
• Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid LeukemiaCompletedNCT01576185
• Studying Dexamethasone and Prednisone Sensitivity in Samples From Younger Patients With High-Risk B-Cell Precursor Acute Lymphoblastic LeukemiaCompletedNCT01553162
• Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic LeukemiaCompletedNCT01540578
• Genetic Test To Identify Previously Undetectable Minimal Residual Disease in Cell Samples From Younger Patients With Acute Lymphoblastic LeukemiaCompletedNCT01533168
• Gene Expression in Samples From Patients With T-Cell Acute Lymphoblastic LeukemiaCompletedNCT01520246
• Studying Biomarker Expression in Samples From Patients With Down Syndrome and Acute Myeloid Leukemia or Other Transient Myeloproliferative DisorderCompletedNCT01511575
• Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical TrialCompletedNCT01507441
• Role of Biomarkers in Disease Progression in Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01500499
• Comparison of Laboratory Test Results of Minimal-Residual Disease in Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01498302
• Study to Predict Risk of Relapse in Bone Marrow Cell Samples From Younger Patients With Acute Myeloid LeukemiaCompletedNCT01438138
• Study of Proteins in Promoting Chemotherapy Resistance in Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01419496
• Study of Gemtuzumab Ozogamicin Therapy in DNA Samples From Patients With Acute Myeloid Leukemia Treated on COG-AAML0531CompletedNCT01407757
• Cell Samples From Patients With LeukemiaCompletedNCT01395628
• Biomarkers in Predicting Response to Treatment in Bone Marrow Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01321385
• Biomarkers in Bone Marrow Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01298414
• Biomarker Study in Bone Marrow Samples From Patients With T-Cell Acute Lymphoblastic LeukemiaCompletedNCT01295476
• Biomarkers in Samples of Bone Marrow From Patients With Acute Myeloid LeukemiaCompletedNCT01290107
• Biomarkers in Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01247584
• Prognostic Biomarkers in Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01245231
• Biomarkers in Tissue Samples From Patients With Acute Promyelocytic LeukemiaCompletedNCT01232855
• Biomarker Study in Tissue Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01232842
• Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's LymphomaCompletedNCT01230983Phase 3
• Biomarkers in Tissue Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01229956
• RNA Biomarkers in Tissue Samples From Infants With Acute Myeloid LeukemiaCompletedNCT01229124
• Biomarkers to Classify Young Patients With Acute Lymphoblastic Leukemia (ALL) and Remission Induction Therapy in Young Patients With B-Precursor ALLCompletedNCT01225874Not applicable
• INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative DiseaseCompletedNCT01164163Phase 1
• Lestaurtinib With or Without Chemotherapy Agents in Samples From Young Patients With LeukemiaCompletedNCT01150669
• Obatoclax Mesylate in Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01150656
• Drug Biomarkers in Cell Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01150058
• Biomarkers in Bone Marrow Samples From Patients With Acute Promyelocytic LeukemiaCompletedNCT01146223
• Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01146210
• Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT01142427
• Biomarker Changes in Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01139931
• Blood and Tumor Tissue Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01139333
• Biomarkers in DNA Samples From Younger Patients With Newly Diagnosed Acute Myeloid Leukemia Receiving Gemtuzumab OzogamicinCompletedNCT01139320
• Biomarkers in Samples From Patients With Down Syndrome and Acute Megakaryoblastic LeukemiaCompletedNCT01139307
• Biomarkers in Young Patients With Acute Myeloid LeukemiaCompletedNCT01138332
• Biomarkers in Patients With Acute Myeloid LeukemiaCompletedNCT01138319
• Biomarkers in Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01138306
• Biomarkers in DNA Samples From Patients With High-Risk Acute Lymphoblastic LeukemiaCompletedNCT01119586
• Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology GroupActive, not recruitingNCT01117168
• Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid LeukemiaCompletedNCT01076569
• Studying Gene Expression in Tissue Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01057303
• Studying Biomarkers in Cell Samples From Young Patients With Acute Myeloid LeukemiaCompletedNCT01057290
• Studying Biomarkers in Cell Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01057199
• Studying Gene Expression in Tissue Samples From Patients With Acute Myeloid LeukemiaCompletedNCT01057095
• Studying Biomarkers in Tissue Samples From Young Patients With Acute Myeloid Leukemia Previously Enrolled on Clinical Trial POG-9421CompletedNCT01035307
• Studying DNA in Blood and Bone Marrow Samples From Younger Patients With Acute Myeloid LeukemiaCompletedNCT01024127
• Studying DNA in Blood and Bone Marrow Samples From Young Patients With Acute Lymphoblastic LeukemiaCompletedNCT01016379
• Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid LeukemiaCompletedNCT01005277
• Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk Acute Lymphoblastic LeukemiaWithdrawnNCT00900445
• Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or RemissionCompletedNCT00899899
• DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic LeukemiaCompletedNCT00899652
• Collecting and Storing Tissue From Young Patients With CancerCompletedNCT00898755
• Identifying Risk Factors for Bone Tissue Death in Young Patients With Acute Lymphoblastic Leukemia Treated on Clinical Trial CCG-1882CompletedNCT00898469
• Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With MethotrexateCompletedNCT00898404
• DNA Analysis of Tumor Tissue Samples From Young Patients With Acute Lymphoblastic LeukemiaCompletedNCT00897507
• Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin LymphomaCompletedNCT00897325
• Laboratory Study of Lymphoblasts in Young Patients With High-Risk Acute Lymphoblastic LeukemiaCompletedNCT00896766
• Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical TrialCompletedNCT00890435
• Risk-Group Classification of Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT00482352