Children's Oncology Group: Neoplasms trials

The registry lists 57 Neoplasms studies with Children's Oncology Group as lead sponsor. 1 are open to participants now and 16 have results posted.

Phase 1 15Phase 2 12Phase 3 7No phase 24(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Project: Every Child for Younger Patients With CancerRecruitingNCT02402244
• Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or LymphomaCompletedNCT03323034Phase 1Results posted
• Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid TumorsCompletedNCT03320330Phase 1/2Results posted
• Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid TumorsCompletedNCT02975882Phase 1Results posted
• Prexasertib in Treating Pediatric Patients With Recurrent or Refractory Solid TumorsCompletedNCT02808650Phase 1Results posted
• Carvedilol in Preventing Heart Failure in Childhood Cancer SurvivorsCompletedNCT02717507Phase 2Results posted
• Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade GliomasCompletedNCT02323880Phase 1Results posted
• Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell TransplantCompletedNCT01817075Phase 3Results posted
• Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid LeukemiaCompletedNCT01307579Phase 3Results posted
• Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or LeukemiaCompletedNCT01154816Phase 2Results posted
• Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyCompletedNCT00716976Phase 3Results posted
• Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell TumorsCompletedNCT00467051Phase 2Results posted
• Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney TumorsCompletedNCT00335556Phase 2Results posted
• Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed GliomasCompletedNCT00100802Phase 2Results posted
• Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell TumorCompletedNCT00085098Phase 3Results posted
• Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell TumorsCompletedNCT00053352Phase 3Results posted
• Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell TumorsCompletedNCT00047320Phase 2Results posted
• Genetic Overlap Between Anomalies and Cancer in Kids in the Children's Oncology Group: The COG GOBACK StudyActive, not recruitingNCT05071859
• Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric OncologyCompletedNCT02847130
• Gene Analysis in Studying Susceptibility to Wilms TumorCompletedNCT01808079
• Studying Biomarkers in Urine Samples From Younger Patients With Wilms TumorCompletedNCT01614808
• Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal TumorsCompletedNCT01572467
• Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their ParentsCompletedNCT01556256Not applicable
• Studying Gene Expression in Samples From Younger Patients With NeuroblastomaCompletedNCT01553448
• Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid TumorWithdrawnNCT01453465
• DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or SiblingsCompletedNCT01434355
• Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor ProgressionCompletedNCT01433224
• Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or LymphomaCompletedNCT01273090Phase 1
• INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative DiseaseCompletedNCT01164163Phase 1
• Biomarkers in Tissue Samples From Patients With High-Risk Wilms TumorCompletedNCT01118078
• Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology GroupActive, not recruitingNCT01117168
• Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain TumorsCompletedNCT00919750
• Collecting and Storing Tissue From Young Patients With CancerCompletedNCT00898755
• Gene Expression Profiles to Categorize Wilms TumorsCompletedNCT00897637
• Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical TrialCompletedNCT00890435
• Neuropsychological and Behavioral Testing in Younger Patients With CancerCompletedNCT00772200
• Palifermin in Preventing Oral Mucositis Caused by Chemotherapy and/or Radiation Therapy in Young Patients Undergoing Stem Cell TransplantWithdrawnNCT00728585Phase 2
• Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to TreatmentWithdrawnNCT00458744Phase 1
• Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell TransplantCompletedNCT00305851Phase 3
• Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid TumorsCompletedNCT00138216Phase 1
• Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS TumorsCompletedNCT00107458Phase 1
• Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer SurvivorsCompletedNCT00082745
• Pemetrexed Disodium in Treating Young Patients With Recurrent Solid TumorsCompletedNCT00070473Phase 1
• Combination Chemotherapy in Treating Children With Newly Diagnosed Malignant Germ Cell TumorsCompletedNCT00066482Not applicable
• Diagnostic Study of Tumor Characteristics in Patients With Ewing's SarcomaCompletedNCT00048984
• Electroacupuncture in Treating Delayed Nausea and Vomiting in Patients Receiving Chemotherapy For Newly Diagnosed Childhood Sarcoma, Neuroblastoma, Nasopharyngeal Cancer, Germ Cell Tumors, or Hodgkin LymphomaCompletedNCT00040911Not applicable
• Irinotecan in Treating Children With Refractory or Advanced Solid Tumors Who Are Receiving AnticonvulsantsCompletedNCT00008424Phase 1
• Ecteinascidin 743 in Treating Children With Refractory Solid TumorsCompletedNCT00006463Phase 1
• Combination Chemotherapy in Treating Children With Solid Tumors That Have Not Responded to Previous TherapyCompletedNCT00006095Phase 1
• Irinotecan in Treating Children With Refractory Solid TumorsCompletedNCT00004078Phase 2
• Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell TumorsCompletedNCT00003811Phase 2
• Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal TumorsCompletedNCT00003203Phase 2
• Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord TumorsCompletedNCT00003141Phase 1
• Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain TumorsCompletedNCT00003096
• Combination Chemotherapy in Treating Children With Progressive Brain TumorsCompletedNCT00002944Phase 3
• Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell TumorsCompletedNCT00002594Phase 2
• Development of Strategies to Increase Enrollment in Clinical Trials for Children With CancerCompletedNCT00002485