Children's Oncology Group: Medulloblastoma trials

The registry lists 14 Medulloblastoma studies with Children's Oncology Group as lead sponsor. 1 are open to participants now and 5 have results posted.

Phase 1 1Phase 2 5Phase 3 7No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing LossRecruitingNCT05382338Phase 3
• Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic MedulloblastomaCompletedNCT02017964Phase 2Results posted
• Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyCompletedNCT00716976Phase 3Results posted
• Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNETCompletedNCT00392327Phase 3Results posted
• Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk MedulloblastomaCompletedNCT00336024Phase 3Results posted
• Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk MedulloblastomaCompletedNCT00085735Phase 3Results posted
• A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT04978727Phase 1
• Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven MedulloblastomaActive, not recruitingNCT02724579Phase 2
• Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain TumorsCompletedNCT00919750
• Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal TumorCompletedNCT00006461Phase 3
• Irinotecan in Treating Children With Refractory Solid TumorsCompletedNCT00004078Phase 2
• Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced MedulloblastomaCompletedNCT00003573Phase 2
• Radiation Therapy Plus Combination Chemotherapy in Treating Children With MedulloblastomaCompletedNCT00002875Phase 3
• Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell TumorsCompletedNCT00002594Phase 2