Children's Oncology Group: Rhabdomyosarcoma trials

The registry lists 31 Rhabdomyosarcoma studies with Children's Oncology Group as lead sponsor. 2 are open to participants now and 8 have results posted.

Phase 1 2Phase 2 8Phase 3 8No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase 1/2 Study of CBX-12 in Children, Adolescents, or Young Adults With Solid Tumors That Have Come Back After Treatment or Are Difficult to TreatNot yet recruitingNCT07830667Phase 1/2
• A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)RecruitingNCT07466316Phase 3
• Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial SarcomaCompletedNCT02452554Phase 2Results posted
• Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell TransplantCompletedNCT01305200Phase 3Results posted
• Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or LeukemiaCompletedNCT01154816Phase 2Results posted
• Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed RhabdomyosarcomaCompletedNCT00354835Phase 3Results posted
• High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or EctomesenchymomaCompletedNCT00354744Phase 3Results posted
• Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell TransplantCompletedNCT00309907Phase 2Results posted
• Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk RhabdomyosarcomaCompletedNCT00075582Phase 3Results posted
• Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of TumorsCompletedNCT00070109Phase 2Results posted
• A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk RhabdomyosarcomaActive, not recruitingNCT04994132Phase 3
• Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid TumorsWithdrawnNCT02011126Phase 2
• Biomarkers in Patients With Advanced RhabdomyosarcomaCompletedNCT01668095
• Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With RhabdomyosarcomaCompletedNCT01626170
• Studying Protein Expression in Tissue Samples From Younger Patients With RhabdomyosarcomaCompletedNCT01609803
• Studying Genes in Samples From Younger Patients With RhabdomyosarcomaCompletedNCT01585376
• Biomarkers in Tumor Tissue Samples From Younger Patients With RhabdomyosarcomaCompletedNCT01496573
• Biomarkers in Patients With RhabdomyosarcomaCompletedNCT01466283
• Studying Biomarkers in Samples From Patients With RhabdomyosarcomaCompletedNCT01433237
• Protein Expression in Samples From Young Patients With RhabdomyosarcomaCompletedNCT01426945
• DNA Tests in Detecting Disseminated Disease in Tumor, Blood, and Bone Marrow Samples From Patients With RhabdomyosarcomaCompletedNCT01419509
• Biomarker in Tumor Tissue Samples From Patients With RhabdomyosarcomaCompletedNCT01365962
• Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine FeaturesCompletedNCT01048892Phase 1
• Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue SarcomaCompletedNCT00919269
• Collecting and Storing Tissue From Young Patients With CancerCompletedNCT00898755
• Evaluating Dactinomycin and Vincristine in Young Patients With CancerCompletedNCT00674193
• Irinotecan in Treating Children With Refractory Solid TumorsCompletedNCT00004078Phase 2
• Combination Chemotherapy in Treating Patients With Previously Untreated RhabdomyosarcomaCompletedNCT00003958Phase 3
• Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or SarcomaCompletedNCT00003955Phase 2
• Genetic Study of Children With Soft Tissue Sarcoma or RhabdomyosarcomaCompletedNCT00003793
• Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed RhabdomyosarcomaCompletedNCT00002995Phase 3