Children's Oncology Group: Sarcoma, Ewing trials

The registry lists 20 Sarcoma, Ewing studies with Children's Oncology Group as lead sponsor. 2 are open to participants now and 5 have results posted.

Phase 1 2Phase 2 9Phase 3 3No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase 1/2 Study of CBX-12 in Children, Adolescents, or Young Adults With Solid Tumors That Have Come Back After Treatment or Are Difficult to TreatNot yet recruitingNCT07830667Phase 1/2
• Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsRecruitingNCT04851119Phase 1/2
• Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or LeukemiaCompletedNCT01154816Phase 2Results posted
• Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of TumorsCompletedNCT00618813Not applicableResults posted
• Cytarabine in Treating Young Patients With Recurrent or Refractory Ewing's SarcomaCompletedNCT00470275Phase 2Results posted
• Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of TumorsCompletedNCT00070109Phase 2Results posted
• Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of TumorsCompletedNCT00061893Phase 2Results posted
• Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the BodyTerminatedNCT06820957Phase 2/3
• Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid TumorsWithdrawnNCT02011126Phase 2
• Genetic Biomarkers in Saliva Samples From Patients With Ewing SarcomaCompletedNCT01876303
• Biomarkers in Tissue Samples From Patients With Ewing SarcomaCompletedNCT01480518
• Biomarker in Tissue Samples From Patients With Ewing SarcomaCompletedNCT01365949
• Collecting and Storing Biological Samples From Patients With Ewing SarcomaCompletedNCT00899990
• Collecting and Storing Tissue From Young Patients With CancerCompletedNCT00898755
• Study of Tumor Samples From Patients With Ewing SarcomaCompletedNCT00898053
• Evaluating Dactinomycin and Vincristine in Young Patients With CancerCompletedNCT00674193
• Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's SarcomaWithdrawnNCT00334867Phase 3
• Diagnostic Study of Tumor Characteristics in Patients With Ewing's SarcomaCompletedNCT00048984
• Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal TumorCompletedNCT00006734Phase 3
• Irinotecan in Treating Children With Refractory Solid TumorsCompletedNCT00004078Phase 2