Clinical trials in Democratic Republic of the Congo
72 studies list at least one site in Democratic Republic of the Congo. 30 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-11-04.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Most studied here
Who runs them
Institute of Tropical Medicine, Belgium (10) · NICHD Global Network for Women's and Children's Health (5) · International Vaccine Institute (4) · National Institute of Allergy and Infectious Diseases (NIAID) (4) · French Africa Pediatric Oncology Group (4) · Novartis Pharmaceuticals (3) · Swiss Tropical & Public Health Institute (3) · Jean-Pierre Van geertruyden (3)
What changed recently
From the registry's own updates since Oct 15, 2026.
Results posted1
Newly registered2
- A Phase III Trial to Evaluate the Safety and Efficacy of Anti-inflammatory Drugs in Addition to Praziquantel in Girls and Women With Female Genital SchistosomiasisNov 4, 2026NCT07915518
- BRAVO is a Phased Outbreak-response Study in the DRC Evaluating ERVEBO® Vaccination in ~20,000 Frontline Workers During the 2026 BDV Outbreak, Step A Assesses Real-world Effectiveness, Safety, and Impact on Severe Disease and Mortality, While Generating Evidence for Future BDV Vaccination StrategiesOct 29, 2026NCT07903350
Studies
Recruiting first, then most recently updated. Showing 50 of 72 — search for more.
- A Phase III Trial to Evaluate the Safety and Efficacy of Anti-inflammatory Drugs in Addition to Praziquantel in Girls and Women With Female Genital SchistosomiasisNot yet recruitingNCT07915518Phase 3
- BRAVO is a Phased Outbreak-response Study in the DRC Evaluating ERVEBO® Vaccination in ~20,000 Frontline Workers During the 2026 BDV Outbreak, Step A Assesses Real-world Effectiveness, Safety, and Impact on Severe Disease and Mortality, While Generating Evidence for Future BDV Vaccination StrategiesRecruitingNCT07903350Phase 4
- Study of Vaccines Against Bundibugyo Virus Disease in Contacts of Cases in the Democratic Republic of the CongoNot yet recruitingNCT07842107Phase 2/3
- RVF and Other Emerging Infectious Diseases in East and Central AfricaRecruitingNCT05139524
- Testing of a New Rapid Antigen Test for Plague in Ituri, Democratic Republic of the Congo.Not yet recruitingNCT07174648
- AI Blind-Sweep Ultrasound for Antenatal Screening by Non-Specialist Health Workers in Rural DR CongoRecruitingNCT07677670
- Evaluation of Effectiveness and Safety of LC16m8 Mpox Vaccine in the Democratic Republic of Congo (DRC)RecruitingNCT07093489
- Low-cost Negative Pressure Wound Therapy vs Standard Dressings for Gustilo IIIb Tibial Fractures (Bukavu Pilot RCT)Not yet recruitingNCT07790991Not applicable
- Stop Transmission of Gambiense Human African TrypanosomiasisRecruitingNCT07789743Phase 3
- Implementation and Evaluation of Vector Control Methods in Kinshasa: The Case of AedesRecruitingNCT06981442Not applicable
- A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in AfricaRecruitingNCT07379580Phase 2
- Surveillance of AMR in DRCRecruitingNCT06821282
- Caffeine for Hypoxic Ischemic EncephalopathyRecruitingNCT06855108Phase 3
- Validation of SDS-EDTA-Treated Chromatography Paper Strips for Mpox Sampling and Transport in DRCRecruitingNCT07634081
- Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health WorkersNot yet recruitingNCT07506967Not applicable
- Therapeutic Recommendations For The Treatment Of Children With A RetinoblastomaRecruitingNCT04425434
- Recommendations for the Treatment of Children With Burkitt's LymphomaRecruitingNCT04425421
- Therapeutic Recommendations for NephroblastomaRecruitingNCT04423484
- Effectiveness of Malaria Vaccines in Reducing the Risk of Invasive Non-typhoidal Salmonella DiseaseRecruitingNCT07416461
- Severe Malaria in Remote Areas- Closing the Evidence GapEnrolling by invitationNCT06806956
- EBOla Post-Exposure ProphylaxisNot yet recruitingNCT06841614Phase 3
- Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE CountriesRecruitingNCT06723392Phase 3
- Maternal Newborn Health RegistryRecruitingNCT01073475
- Clinical Aspects, Management and Surveillance of Febrile Illnesses in DRCRecruitingNCT07345286
- Preventative Intervention for Cholera for 7 DaysRecruitingNCT05166850Not applicable
- Nutritional Intervention With Tenebrio Molitor Powder in Children With Chronic Malnutrition in the Democratic Republic of the CongoNot yet recruitingNCT07284095Not applicable
- Hospital Based Registry of Childhood Cancer in Pediatric Oncology Units in French Speaking AfricaRecruitingNCT03803735
- Epidemiological and Clinical Characteristics of Human Mpox Outbreak in Equateur Province in the Democratic Republic of Congo (Part2)Enrolling by invitationNCT07067723
- Global Burden Estimation of Human Papillomavirus (GLOBE-HPV)RecruitingNCT06129253
- Epidemiological and Clinical Characteristics of Mpox Outbreak in Equateur, the DR Congo (Part1)Enrolling by invitationNCT07055867
- Efficacy, Safety and Tolerability of KLU156 in Adults and Children With Uncomplicated P. Falciparum MalariaCompletedNCT05842954Phase 3
- Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity DiagnosticsActive, not recruitingNCT05757167Phase 4
- Financially-Incentives to Improve Provider ComplianceCompletedNCT04634019Not applicable
- Bedside Improvement of Resuscitation Through mHealth Feedback (BIRTH Study)CompletedNCT05963516Not applicable
- Mpox Paediatric and Adolescent Clinical StudyCompletedNCT05947786
- Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster RCTActive, not recruitingNCT05745987Phase 4
- Study to Evaluate the Immunogenicity and Safety of a Heterologous Vaccine Regimen Against EbolaCompletedNCT04186000Phase 2
- Prevention of Iron Deficiency Anemia Post-deliveryCompletedNCT05590260Phase 3
- Realizing Effectiveness Across Continents With Hydroxyurea (REACH)Active, not recruitingNCT01966731Phase 1/2
- Mpox Biology, Outcome, Transmission and Epidemiology - Tracking the Immune Response After mpoX vaCcination (MBOTE-TRAXX): Clinical Study to Monitor the Immunological Response Following Mpox Vaccination in the City of Kinshasa, Democratic Republic of the CongoActive, not recruitingNCT07499739Phase 4
- An Immunogenicity and Safety Trial of MVA-BN in Adults Living With HIV for the Prevention of Mpox Infection, in Kinshasa, DRCActive, not recruitingNCT06839989Phase 2
- Investigating MPXV Viral Clearance in Mpox Cases and Secondary Attack Rate in ContactsCompletedNCT07267390
- Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRCActive, not recruitingNCT06844487Phase 3
- JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the CongoCompletedNCT02977715Phase 3
- Realizing Effectiveness Across Continents With HydroxyureaActive, not recruitingNCT06171217Phase 2
- To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum MalariaCompletedNCT04675931Phase 2
- Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric PatientsCompletedNCT05433350Phase 2/3
- Surveillance of Vaccine-induced Immunity Against Ebola in Previously Vaccinated Health Care WorkersCompletedNCT05313139
- Azithromycin Reduction to Reach Elimination of Trachoma BWithdrawnNCT06289647Phase 4
- Ocular Complications of Mpox in the Democratic Republic CongoCompletedNCT06579885