Hemorrhagic Fever, Ebola clinical trials
The registry lists 104 studies for Hemorrhagic Fever, Ebola across more than 10 countries. 13 are recruiting or about to start. 102 of them are mainly about Hemorrhagic Fever, Ebola (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29.
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (20) · University of Oxford (8) · Janssen Vaccines & Prevention B.V. (7) · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation (6) · London School of Hygiene and Tropical Medicine (5) · Institute of Tropical Medicine, Belgium (5) · ANRS, Emerging Infectious Diseases (3) · Jiangsu Province Centers for Disease Control and Prevention (3)
What is being tested here
Drugs under test in Hemorrhagic Fever, Ebola studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7, phase 3 first
- Apr 2027Study of Vaccines Against Bundibugyo Virus Disease in Contacts of Cases in the Democratic Republic of the Congo · Phase 3 · Jean-Pierre Van geertruyden
- Aug 2027EBOla Post-Exposure Prophylaxis · Phase 3 · ANRS, Emerging Infectious Diseases
- Nov 2026REVIVE (Response to the Ebola Virus Vaccine) · Tulane University
- Apr 2027A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health · International AIDS Vaccine Initiative
- Jun 2027BRAVO is a Phased Outbreak-response Study in the DRC Evaluating ERVEBO® Vaccination in ~20,000 Frontline Workers During the 2026 BDV Outbreak, Step A Assesses Real-world Effectiveness, Safety, and Impact on Severe Disease and Mortality, While Generating Evidence for Future BDV Vaccination Strategies · Epicentre
- Aug 2027Impact of Delay Between Administration of Inmazeb Administration and Vaccination by Ervebo on Vaccine Immune Response on Healthy Volunteers · ANRS, Emerging Infectious Diseases
- Aug 2027Immunology of Ebola Vaccine · Emory University
Who these studies take
Of the 4 Hemorrhagic Fever, Ebola studies recruiting now, 2 (50%) set no upper age limit and 2 (50%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (100%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (100%) | 4 (100%) |
| 30 | 4 (100%) | 4 (100%) |
| 40 | 4 (100%) | 4 (100%) |
| 50 | 4 (100%) | 4 (100%) |
| 65 | 2 (50%) | 2 (50%) |
| 75 | 2 (50%) | 2 (50%) |
| 85 | 2 (50%) | 2 (50%) |
Across all 104 studies, recruiting or not: 61% stop at 75 or younger and 55% at 65; 32% take children; 0% are for women only and 1% for men only; 75% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hemorrhagic Fever, Ebola studies take
Of 16 phase 1 interventional studies under Hemorrhagic Fever, Ebola, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 16 mo10–23 · 16 studies | — | — |
| Phase 2 | 32 mo4–39 · 13 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 104. Browse all 104 → or search them.
- BRAVO is a Phased Outbreak-response Study in the DRC Evaluating ERVEBO® Vaccination in ~20,000 Frontline Workers During the 2026 BDV Outbreak, Step A Assesses Real-world Effectiveness, Safety, and Impact on Severe Disease and Mortality, While Generating Evidence for Future BDV Vaccination StrategiesRecruitingNCT07903350Phase 41 country
- R3470-3471-3479 (REGN-EB3) Expanded Access Protocol (EAP) for Treatment of Ebola Virus DiseaseAvailableNCT03576690
- Study of Vaccines Against Bundibugyo Virus Disease in Contacts of Cases in the Democratic Republic of the CongoNot yet recruitingNCT07842107Phase 2/31 country
- A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General HealthRecruitingNCT07565090Phase 11 country
- Clinical Validation of Isothermal Nucleic Acid Amplification Bioassays Modules - DRCNot yet recruitingNCT07688083
- Clinical Validation of Isothermal Nucleic Acid Amplification Bioassays Modules - GUINEANot yet recruitingNCT07681752
- Impact of Delay Between Administration of Inmazeb Administration and Vaccination by Ervebo on Vaccine Immune Response on Healthy VolunteersNot yet recruitingNCT05202288Phase 2
- EBOla Post-Exposure ProphylaxisNot yet recruitingNCT06841614Phase 34 countries
- Safety and Immunogenicity of Ervebo® and Zabdeno® Booster Vaccines Against Ebola Virus Following Previous Vaccination with the Zabdeno/Mvabea® or Ervebo® Vaccine Schedules in DRCRecruitingNCT06126822Phase 31 country
- Open-Label Expanded Access for Ebola-Infected Patients to Receive Human MAb Ansuvimab As Therapeutic or for HR PEPAvailableNCT05067166
- Safety and Immunogenicity of rVSVΔG-ZEBOV-GP Vaccination When Dosed Concurrently With mRNA COVID-19 Vaccine Booster DosesNot yet recruitingNCT06587503Phase 4
- Addressing Medium- to Long-term EBOLA Associated Psychological Distress and Psychosocial Problems in Central UgandaRecruitingNCT06093646Not applicable1 country
- Community Preparedness for Outbreak Response and Readiness for Ebola Vaccination in LiberiaNot yet recruitingNCT058886491 country
- Long-Term Neurologic and Neurocognitive Sequelae Following Pediatric Ebola Virus in LiberiaCompletedNCT068111291 country
- Study to Evaluate the Immunogenicity and Safety of a Heterologous Vaccine Regimen Against EbolaCompletedNCT04186000Phase 21 country
- Immunity Induced by VSV-EBOV and Assessment of a Booster Dose in Individuals at Potential Occupational Risk for ExposureWithdrawnNCT05959421Phase 31 country
- REVIVE (Response to the Ebola Virus Vaccine)Active, not recruitingNCT05992480Phase 41 country
- Evaluating the Live-Attenuated Human Parainfluenza Virus Type 3 Vectored Vaccine Candidate Expressing Ebolavirus Zaire Glycoprotein as the Sole Envelope GlycoproteinTerminatedNCT03462004Phase 11 country
- Immunology of Ebola VaccineActive, not recruitingNCT06100913Phase 21 country
- African-Canadian Study of HIV-Infected Adults and a Vaccine for Ebola - ACHIV-EbolaCompletedNCT03031912Phase 21 country
- A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO ZTerminatedNCT02451891Phase 11 country
- Efficacy of Favipiravir Against Ebola (JIKI)CompletedNCT02329054Phase 21 country
- Evaluation and Support to EVD Cured Patients and Their Contacts (Les Vainqueurs d'Ebola)CompletedNCT044094051 country
- A Trial to Evaluate the Safety and Systems Biology Response of Ebolavirus Zaire Vaccine (ChAd3-EBO-Z)CompletedNCT03583606Phase 11 country
- A Safety Trial to Test MVA-BN(R)-Filo and Ad26.ZEBOV Vaccines in Healthy VolunteersCompletedNCT02891980Phase 11 country
- Natural History, Disease Progression, and Long-Term Neurologic Sequelae of Ebola Virus Disease (EVD) Survivors in PREVAIL IIICompletedNCT054948011 country
- A Study to Evaluate the Immunogenicity, Safety and Tolerability of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult ParticipantsCompletedNCT02543268Phase 31 country
- A Study of 2-dose Vaccine Regimen Using 3 Consecutive Lots of Ad26.ZEBOV and MVA-BN-Filo in Adult ParticipantsCompletedNCT04228783Phase 31 country
- A Study of 2-dose Vaccination Regimen of Ad26.ZEBOV and MVA-BN-Filo in InfantsCompletedNCT03929757Phase 22 countries
- A Study to Evaluate A Range of Dose Levels of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult ParticipantsCompletedNCT02543567Phase 31 country
- Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone StudyCompletedNCT05284097Phase 21 country
- A Study of a New Vaccine Against Two Types of EbolaCompletedNCT05079750Phase 11 country
- Safety, Tolerability and Immunogenicity Study of 2-dose Heterologous Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-FiloCompletedNCT02598388Phase 26 countries
- Partnership for Research on Ebola VACcinationsCompletedNCT02876328Phase 24 countries
- Long-term Safety Follow-up of Participants Exposed to the Candidate Ebola Vaccines Ad26.ZEBOV and/or MVA-BN-FiloTerminatedNCT02661464Phase 37 countries
- Ad26.ZEBOV Booster in Children Previously Vaccinated With Ad26.ZEBOV and MVA-BN-Filo (EBOVAC Booster Study)CompletedNCT04711356Phase 21 country
- Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, GabonCompletedNCT05130398Phase 1/21 country
- Ad26.ZEBOV Booster in HIV+ Adults Previously Vaccinated With Ad26.ZEBOV/MVA-BN-Filo (EBOVAC HIV+ Booster Study)CompletedNCT05064956Phase 22 countries
- EBOVAC-Salone ExtensionCompletedNCT038207391 country
- A Study in Tanzania of a New Vaccine Against Two Types of EbolaStatus unknownNCT05301504Phase 11 country
- Ebola Virus Disease Survivors: Clinical and Immunologic Follow-upCompletedNCT024319232 countries
- PREVAIL VI: Identification of Host Genetic Factors Underlying Ebola Virus Disease Risk, Mortality, Long-term Sequelae, Viral RNA Persistence, Humoral Immunity, and Ebola Vaccine ResponseCompletedNCT030988621 country
- Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy AdultsCompletedNCT04723602Phase 11 country
- Staged Phase 3 Study to Assess the Safety and Immunogenicity of Ebola Candidate Vaccines Ad26.ZEBOV and MVA-BN-FiloCompletedNCT02509494Phase 31 country
- INO-4201 as Booster in Healthy VSV-ZEBOV VaccineesCompletedNCT04906629Phase 11 country
- Safety, Tolerability and Immunogenicity Study of 3 Prime-boost Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-Filo in Healthy Adults, Children and Human Immunodeficiency Virus Positive (HIV+) AdultsCompletedNCT02564523Phase 24 countries
- GS-5734 to Assess the Antiviral Activity, Longer-Term Clearance of Ebola Virus, and Safety in Male Ebola Survivors With Evidence of Ebola Virus Persistence in SemenCompletedNCT02818582Phase 22 countries
- Study to Evaluate the Immunogenicity and Safety of an Ebola Virus (EBOV) Glycoprotein (GP) Vaccine in Healthy SubjectsCompletedNCT02370589Phase 11 country
- Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRCStatus unknownNCT04152486Phase 31 country
- Prophylaxis Vaccine Antibodies EbolaStatus unknownNCT04822376Phase 21 country