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Malaria, Falciparum clinical trials

The registry lists 455 studies for Malaria, Falciparum across more than 10 countries. 37 are recruiting or about to start. 345 of them are mainly about Malaria, Falciparum (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Status

Completed
339
Status unknown
25
Terminated
24
Recruiting
21
Not yet recruiting
16
Active, not recruiting
15

Phase

Phase 1
137
Phase 2
110
Phase 4
62
Phase 3
61
Early Phase 1
4

Where

Burkina Faso
52
Tanzania
43
Kenya
42
Mali
37
United States
35
Uganda
27

Who runs them

University of Oxford (54) · National Institute of Allergy and Infectious Diseases (NIAID) (38) · Sanaria Inc. (29) · London School of Hygiene and Tropical Medicine (21) · GlaxoSmithKline (21) · Medicines for Malaria Venture (20) · Radboud University Medical Center (20) · U.S. Army Medical Research and Development Command (14)

What is being tested here

Drugs under test in Malaria, Falciparum studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Amodiaquine2519
KLU156214
NITD 609204
Piperaquine1526
Artenimol1423
PfSPZ Challenge1012
INE963103
Imatinib103
Sulfadoxine113
Pyrimethamine113

Coming up

5phase 3 studies under way
20studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 21 Malaria, Falciparum studies recruiting now, 5 (24%) set no upper age limit and 15 (71%) stop at 75 or younger. 14 (67%) take children under 18. 2 (10%) are for women only and 0 (0%) for men only; 9 (43%) take healthy volunteers.

Recruiting studies that take each age, of 21
AgeWomenMen
1010 (48%)10 (48%)
1815 (71%)13 (62%)
3014 (67%)13 (62%)
4013 (62%)13 (62%)
5012 (57%)12 (57%)
658 (38%)8 (38%)
756 (29%)6 (29%)
856 (29%)6 (29%)

Across all 455 studies, recruiting or not: 75% stop at 75 or younger and 73% at 65; 61% take children; 5% are for women only and 3% for men only; 55% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Malaria, Falciparum studies take

Of 49 phase 1 interventional studies under Malaria, Falciparum, half reached primary completion within 13 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 113 mo7–18 · 49 studies—12 mo5–24 · 29 studies
Phase 1/232 mo18–50 · 13 studies——
Phase 213 mo8–21 · 39 studies——
Phase 321 mo14–28 · 23 studies——
Phase 416 mo6–29 · 23 studies——
Interventional, no phase20 mo8–31 · 24 studies——
Observational19 mo11–43 · 20 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

Results posted1

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 455. Browse all 455 → or search them.