An observational study in Nephroblastoma, sponsored by French Africa Pediatric Oncology Group. Recruiting at 7 sites in 6 countries. Open to participants aged 6 Months to 18 Years. Per ClinicalTrials.gov, last updated 2026-03-02.
Sponsored by French Africa Pediatric Oncology Group · Observational
The study is based on results form 2 previous studies carried out by the GFAOP. The aim of this study is to evaluate the capacity of units to follow the recommendations in the protocol.
The study is based on results form 2 previous studies carried out by the GFAOP. This study aims to evaluate the capacity of units to follow the recommendations in the protocol. It will look mainly at treatment compliance and outcome for the children treated. The study will also evaluate the improvement in treatment compliance and reporting. This work will help the group to evaluate future needs in participating units and help us adapt treatment programmes to local conditions.
All children with local Nephroblastoma in all participating units
Unilateral Nephroblastoma Tumor Not previously treated The general health of the child will permit treatment.
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Exclusion Criteria:
Bilateral Nephroblastoma tumor Previously treated Disease too advanced Doubt concerning the diagnosis Treatment Refusal
All children coming into the participating units with suspected Nephroblastoma.
Other: Data collection
Clinical stage, treatment given and observations of toxicity if any, outcome following treatment and follow up.
Evaluation of the number of cases with local disease.
By evaluating the initial clinical reports and later histological reports to confirm the stage and the diagnosis.
Time frame: 5 years
Evaluation of the number of cases with stage IV disease.
By evaluating the initial clinical reports and later histological reports to confirm the stage.
Time frame: 5 Years
Evaluating the treatment given.
Comparison of treatment given and recommended treatment.
Time frame: 5 Years
Evaluating the follow up after treatment.
How many children alive or dead after treatment
Time frame: 5 Years
Why has treatment failed
look at precision of reporting by comparing reports (histological and surgical)
Time frame: 5 years
Plan to share: Undecided
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French Africa Pediatric Oncology Group