Osteogenesis Imperfecta clinical trials
The registry lists 85 studies for Osteogenesis Imperfecta across more than 10 countries. 20 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-22.
Status
- Completed
- 42
- Recruiting
- 14
- Active, not recruiting
- 11
- Not yet recruiting
- 6
- Terminated
- 6
- Status unknown
- 4
Phase
- Phase 2
- 15
- Phase 1
- 10
- Phase 3
- 10
- Phase 4
- 6
Where
- United States
- 38
- France
- 16
- Canada
- 15
- Italy
- 14
- United Kingdom
- 10
- Germany
- 9
Who runs them
Ultragenyx Pharmaceutical Inc (7) · Baylor College of Medicine (6) · Assiut University (5) · Amgen (5) · Istituto Ortopedico Rizzoli (5) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (4) · Angitia Incorporated Limited (2) · Sheffield Children's NHS Foundation Trust (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 85 — search for more.
- A Dose REgimen-Finding Study of AGA2115 in Chinese Patients With Osteogenesis ImpeRfecta (EIR)RecruitingNCT07557446Phase 21 country
- BBD Longitudinal Study of Osteogenesis ImperfectaRecruitingNCT024326252 countries
- Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)RecruitingNCT07062588Phase 28 countries
- Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical DiagnosisNot yet recruitingNCT07666269Not applicable1 country
- Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis ImperfectaRecruitingNCT07366086Phase 33 countries
- GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP)Not yet recruitingNCT075946391 country
- Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Osteogenesis ImperfectaRecruitingNCT05927389Not applicable1 country
- Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI)Not yet recruitingNCT05559801Phase 1/2
- Effects of Bisphosphonates on OI-Related Hearing LossRecruitingNCT04152551Phase 41 country
- An Interventional Study to Evaluate the Impact of Blood Flow Restriction Training on Muscle, Bone, and Quality of Life in Adults With Osteogenesis Imperfecta Type IRecruitingNCT07478224Not applicable1 country
- REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)RecruitingNCT07412782Not applicable1 country
- Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis ImperfectaRecruitingNCT072872411 country
- Registry of Osteogenesis ImperfectaRecruitingNCT041157741 country
- Pediatric Arthropathy Beyond Inflammation: Clinical Spectrum and Diagnostic Approach at Assiut University Children HospitalNot yet recruitingNCT07173010
- Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis ImperfectaRecruitingNCT054199601 country
- Social Cognition in Dystrophinopathies and Neurodevelopmental DisordersNot yet recruitingNCT06874166
- Management of Combined Fracture Neck of Femur and Femoral Deformity in Osteogenesis Imperfecta PatientRecruitingNCT05878548Not applicable1 country
- Study of Osteogenesis Imperfecta TendonRecruitingNCT060651111 country
- Osteogenesis Imperfecta and BalanceRecruitingNCT06010134Not applicable1 country
- Site Preservation After Tooth ExtractionNot yet recruitingNCT05258019
- Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and Genotype Phenotype CorrelationCompletedNCT035752211 country
- Evaluation and Intervention for the Effects of Osteogenesis ImperfectaCompletedNCT000015941 country
- Evaluation and Treatment of Patients With Connective Tissue DiseaseCompletedNCT000768301 country
- Clear Aligners for the Treatment of Dental Malocclusion in OIActive, not recruitingNCT04815564Not applicable2 countries
- Setrusumab in Pediatric Japanese Subjects With Osteogenesis ImperfectaActive, not recruitingNCT06636071Phase 31 country
- Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic AcidCompletedNCT03735537Phase 42 countries
- Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis ImperfectaActive, not recruitingNCT05972551Phase 318 countries
- Increasing Knowledge on Osteogenesis Imperfecta by Collecting Epidemiological DataCompletedNCT06193642Not applicable1 country
- Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708Active, not recruitingNCT053176371 country
- Setrusumab vs Placebo for Osteogenesis ImperfectaActive, not recruitingNCT05125809Phase 2/311 countries
- Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis ImperfectaActive, not recruitingNCT05768854Phase 37 countries
- Dental Malocclusion and Craniofacial Development in OIActive, not recruitingNCT029344512 countries
- Post-market Observational Study on JTIN Telescopic Nail in Osteogenesis Imperfecta Pediatric PatientsCompletedNCT056121391 country
- Urinary Biomarkers of OI PathobiologyActive, not recruitingNCT025310872 countries
- Boost Brittle Bones Before BirthActive, not recruitingNCT03706482Phase 1/21 country
- Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)TerminatedNCT05231668Phase 14 countries
- Evaluation of the Benefits of Adaptive Physical Activity in Children and Adolescents With Osteogenesis ImperfectaCompletedNCT04119388Not applicable1 country
- Epigenetic Regulation of Osteogenesis Imperfecta Severity : miROI StudyCompletedNCT04009733Not applicable1 country
- Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis ImperfectaTerminatedNCT05312697Phase 21 country
- Osteogenesis Imperfecta Blood Pressure StudyCompletedNCT041695681 country
- Ready to Sail: Evaluating Sailing's Feasibility as ErgotherapyCompletedNCT06397443Not applicable1 country
- A First-in-Human Study Evaluating AGA2115 in Adult Healthy VolunteersCompletedNCT06086613Phase 11 country
- Safety of Fresolimumab in the Treatment of Osteogenesis ImperfectaCompletedNCT03064074Phase 11 country
- Telescoping Nail in Osteogenesis ImperfectaActive, not recruitingNCT06591546Not applicable1 country
- e-Health Care Method for Patients With Osteogenesis Imperfecta (Tele OI)CompletedNCT06555536Not applicable1 country
- Study to Evaluate Romosozumab in Children and Adolescents With Osteogenesis ImperfectaCompletedNCT04545554Phase 18 countries
- Tranexamic Acid During Telescoping Nail Application In Osteogenesis ImperfectaCompletedNCT05321199Not applicable1 country
- Mesenchymal Stem Cell Based Therapy for the Treatment of Osteogenesis ImperfectaCompletedNCT02172885Phase 11 country
- Prevention of Post Operative Bone Loss in ChildrenCompletedNCT00655681Not applicable1 country
- A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804CompletedNCT03118570Phase 25 countries