Drug
Timolol clinical trials
Also written Timoptic.
- studies test it
- 81
- open now
- 7
- in phase 3
- 16
- first study started
- 1993
Keep track of what changes. Save the Timolol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Studies by the year they started
80 studies that test it; most in 2010 (6)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1998 | 1 |
| 1999 | 1 |
| 2000 | 1 |
| 2002 | 1 |
| 2003 | 1 |
| 2005 | 4 |
| 2006 | 4 |
| 2007 | 2 |
| 2008 | 3 |
| 2009 | 3 |
| 2010 | 6 |
| 2011 | 6 |
| 2012 | 4 |
| 2013 | 2 |
| 2014 | 6 |
| 2015 | 5 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 4 |
| 2019 | 4 |
| 2020 | 3 |
| 2021 | 2 |
| 2023 | 3 |
| 2024 | 2 |
| 2025 | 2 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 10
- Phase 2
- 21
- Phase 3
- 16
- Phase 4
- 22
- No phase
- 14
What it is tested for
Each study’s main condition, where its own words name it.
- Glaucoma
- 22
Who runs them
Industry 23 · Other 58
Allergan (8) · Aristotle University Of Thessaloniki (3) · Alcon Research (3) · Medical University of Vienna (3) · Auson Pharmaceuticals Inc. (2) · University of Nebraska (2) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (2) · Wills Eye (2)
Often tested with
Tested in the same studies.
Dorzolamide (16) · Latanoprost (14) · Bimatoprost (10) · Brimonidine (9) · Travoprost (7) · Brimonidine Tartrate, Timolol Maleate Drug Combination (4) · Hypromellose Derivatives (3) · Xalacom (2)
Studies
Open first, then newest update. How each study uses Timolol is read from its arms, and is right about nine times in ten.
Testing it · 81
- The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label TrialNot yet recruitingPhase 2Geisinger ClinicNCT07583862Written as Topical Timolol
- Topical 0.5% Timolol Solution for Healing Lower Extremity WoundsRecruitingPhase 1Icahn School of Medicine at Mount SinaiNCT06941467Written as Timolol Maleate Solution
- Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds HealingNot yet recruitingPhase 2University of California, DavisNCT07384767Written as Timolol 0.5% Ophthalmic Solution
- Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne VulgarisRecruitingEarly Phase 1Pham Ngoc Thach University of MedicineNCT07474883Written as Timolol 0.5% Ophthalmic Solution
- Efficacy and Safety of Add-on Timolol for EGFR-TKI and ALK-TKI Induced ParonychiaRecruitingPhase 3Queen Mary Hospital, Hong KongNCT06643416Written as Timolol 0.5% eye drops and betamethasone valerate 0.1% cream
- Efficacy and Safety of Timolol for TKI Induced ParonychiaRecruitingPhase 3Queen Mary Hospital, Hong KongNCT06140186Written as Topical Timolol
- A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in NewbornRecruitingNot applicableMassachusetts General HospitalNCT01873131Written as topical timolol maleate
- Comparison of Fractional CO2 Laser Monotherapy and Its Combination With Either Topical Vitamin C or Topical Timolol in the Treatment of Post-Acne Erythema: A Split Face StudyCompletedPhase 2Cairo UniversityNCT07884565Written as topical Timolol maleate 0.5% eye drops
- Prophylactic Use of Timolol Maleate to Prevent Intraocular Pressure Elevation After Nd:YAG Laser Posterior CapsulotomyCompletedNot applicableCMH Multan Institute of Medical SciencesNCT07729189Written as Timolol Maleate
- Aqueous Humor Dynamic Components That Determine Intraocular Pressure VarianceCompletedPhase 4Ohio State UniversityNCT04412096Written as Timolol 0.5% ophthalmic solution
- Topical Timolol Benefit in Venous UlcersCompletedPhase 2Centre Hospitalier Universitaire, AmiensNCT02422017Written as Timolol
- Stop Retinal Ganglion Cell Dysfunction StudyTerminatedPhase 3University of MiamiNCT02390284Written as Timolol
- Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)CompletedPhase 2Hospices Civils de LyonNCT02484716Written as Timolol nasal spray
- Beta Adrenergic Antagonist for the Healing of Chronic DFUCompletedPhase 3VA Office of Research and DevelopmentNCT03282981Written as Timolol
- Evaluate the Safety, Tolerance, and Pharmacokinetic Profiles of Timolol Maleate GelCompletedPhase 1Auson Pharmaceuticals Inc.NCT06824948Written as Timolol Maleate Gel
- Timolol Maleate Gel for the Treatment of Infantile HemangiomaCompletedPhase 2/3Auson Pharmaceuticals Inc.NCT06677853Written as Timolol Maleate Gel
- Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and SafetyCompletedPhase 4Laboratorios PoenNCT05857267Written as Dorzolamide / Timolol Ophthalmic Solution
- How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?TerminatedPhase 4CT Glaucoma AssociatesNCT06369077Written as dorzolamide/timolol
- Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma PatientsCompletedPhase 4Universitaire Ziekenhuizen KU LeuvenNCT02053298Written as Timolol & Dorzolamide
- Comparison of Latanoprost Vs. TimololTerminatedPhase 2University of NebraskaNCT00579969Written as Timolol
See all 81 studies that test Timolol →
Given in every arm · 6 — Timolol is usual care beside what is tested
- Adaptive Optics OCT Evaluation of Rhopressa's Effects on the Retinal Ganglion Cells in Glaucoma PatientsRecruitingPhase 4Brett KingNCT07847073Written as Timolol Maleate 0.25% Ophthalmic Solution
- Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus LazertinibActive, not recruitingPhase 2Janssen Research & Development, LLCNCT06120140Written as Timolol
- Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedPhase 3AllerganNCT02250651Written as Active Comparator: Timolol 0.5%
- Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular HypertensionCompletedPhase 3AllerganNCT02247804Written as Active Comparator: Timolol 0.5%
- The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.WithdrawnPhase 4Stanford UniversityNCT01927406Written as Timolol
- A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular HypertensionCompletedPhase 3Alcon ResearchNCT00465803Written as Timolol maleate ophthalmic solution, 0.5%
As the comparator · 61 — what is tested is compared with Timolol
- Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral ImplantRecruitingPhase 2Glaukos CorporationNCT07075718Written as Timolol eye drops 0.5%
- Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract SurgeryRecruitingPhase 1/2EyeD PharmaNCT07036510Written as Timolol eye drops 0.5%
- Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral ImplantRecruitingPhase 3Glaukos CorporationNCT07495852Written as Timolol eye drops 0.5%
- Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)RecruitingPhase 3SpyGlass Pharma, Inc.NCT07218796Written as Timolol Maleate Ophthalmic Solution, 0.5%
- Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)RecruitingPhase 3SpyGlass Pharma, Inc.NCT07218783Written as Timolol Maleate Ophthalmic Solution, 0.5%
- Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular HypertensionRecruitingPhase 2Glaukos CorporationNCT06152861Written as Timolol maleate ophthalmic solution, 0.5%
- Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular HypertensionCompletedPhase 2Bausch & Lomb IncorporatedNCT07168902Written as Timolol maleate 0.5%
- Study of an Investigational Product, QLS-111, Provided as an Eyedrop, for Treatment of Normal Tension Glaucoma (NTG)CompletedPhase 2Qlaris Bio, Inc.NCT06030193Written as Timolol Maleate PF 0.5% Ophthalmic Solution (Timolol)
- Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile HemangiomasTerminatedPhase 4The University of Texas Health Science Center, HoustonNCT05479123Written as Timolol
- Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedPhase 2D. Western Therapeutics Institute, Inc.NCT05913232Written as Timolol 0.5%
- Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic SolutionActive, not recruitingPhase 1/2SpyGlass Pharma, Inc.NCT06120842Written as Timolol Maleate Ophthalmic Solution, 0.5%
- Safety and IOP-Lowering Effects of WB007CompletedPhase 1/2Bausch & Lomb IncorporatedNCT04149899Written as Timolol 0.5%
- PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM)TerminatedPhase 3Laboratorios Sophia S.A de C.V.NCT03193333Written as Timolol eye drops
- A Study to Evaluate Safety and Tolerability of QLS-101 in NTGCompletedPhase 2Qlaris Bio, Inc.NCT04857827Written as Timolol maleate PF 0.5% ophthalmic solution
- Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).CompletedPhase 2Qlaris Bio, Inc.NCT04830397Written as Timolol Maleate
- Triplenex (triple Fixed Combination) Use Evaluation in Patients with GlaucomaActive, not recruitingPhase 4Federal University of São PauloNCT06761313Written as Bimatoprost .03% sterile ophthalmic solution
- Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic SolutionCompletedPhase 2Glaukos CorporationNCT02754596Written as Timolol Maleate Ophthalmic Solution, 0.5%
- A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 StudyCompletedPhase 3Santen Inc.NCT03691649Written as Timolol Maleate Ophthalmic Solution 0.5%
- A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 MonthsCompletedPhase 2Aerie PharmaceuticalsNCT01699464Written as Timolol maleate ophthalmic solution 0.5%
- A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 StudyCompletedPhase 3Santen Inc.NCT03691662Written as Timolol Maleate Ophthalmic Solution 0.5%
Showing 20 of 61.
Codes
What other systems call Timolol · ClinicalTrials.gg INT008327
- MeSH (NLM) D013999TimololConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 817W3C6175TIMOLOLConfirmed FDA, NLM, Wikidata
- RxNorm 221172Confirmed FDA, Wikidata
- Wikidata Q27128592(S)-timolol hemihydrateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47757TimololConfirmed FDA, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D013999 | Timolol | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 817W3C6175 | TIMOLOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 221172 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27128592 | (S)-timolol hemihydrate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47757 | Timolol | Confirmed FDA, Wikidata |
Also registered as timolol maleate (UNII P8Y54F701R · RxNorm 42933).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.