Epistaxis clinical trials
The registry lists 96 studies for Epistaxis across more than 10 countries. 22 are recruiting or about to start. 60 of them are mainly about Epistaxis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Assiut University (6) · University of Zurich (3) · Cure HHT (3) · Bezmialem Vakif University (3) · Buddhist Tzu Chi General Hospital (2) · University of California, San Diego (2) · Ajou University School of Medicine (2) · Unity Health Toronto (2)
What is being tested here
Drugs under test in Epistaxis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pazopanib | 1 | 1 | 2 |
| Topical Sirolimus | 1 | 0 | 1 |
| Ascorbic Acid | 1 | 0 | 1 |
| Hyaluronic Acid | 1 | 0 | 1 |
| Petrolatum | 1 | 0 | 1 |
| Orange | 1 | 0 | 1 |
| Nintedanib | 1 | 0 | 1 |
| Tranexamic Acid | 0 | 2 | 6 |
| Bevacizumab | 0 | 1 | 5 |
| FloSeal Matrix | 0 | 0 | 2 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 2 open · Angiogenesis inhibitors 6
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Efficacy of Nintedanib for Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) Patients · Dr. Romain Lazor
- Dec 2026Medico-economic Evaluation of Management Strategies for Severe Epistaxis · University Hospital, Toulouse
- Feb 2027Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen Block · Sheikh Zayed Federal Postgraduate Medical Institute
- May 2027The Efficacy of Local Application of B-sitosterol Versus Vasline in Cases of Idiopathic Epistaxis · Assiut University
- Nov 2027Effect of Vitamin C Administration on Intraoperative Bleeding in Patients Undergoing Sinusoscopy · Assiut University
Who these studies take
Of the 10 Epistaxis studies recruiting now, 8 (80%) set no upper age limit and 2 (20%) stop at 75 or younger. 1 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (10%) | 1 (10%) |
| 18 | 10 (100%) | 10 (100%) |
| 30 | 10 (100%) | 10 (100%) |
| 40 | 10 (100%) | 10 (100%) |
| 50 | 10 (100%) | 10 (100%) |
| 65 | 9 (90%) | 9 (90%) |
| 75 | 8 (80%) | 8 (80%) |
| 85 | 8 (80%) | 8 (80%) |
Across all 96 studies, recruiting or not: 28% stop at 75 or younger and 22% at 65; 20% take children; 0% are for women only and 0% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Epistaxis studies take
Of 24 interventional studies with no phase under Epistaxis, half reached primary completion within 14 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 14 mo3–25 · 24 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered2
- Safety and Feasibility of the JStop™ Hemostatic Device for Nosebleeds in the Emergency DepartmentNov 10, 2026NCT07928739
- Nurse-Delivered First-Aid Education for Recurrent Pediatric EpistaxisOct 27, 2026NCT07898644
Studies
Recruiting first, then most recently updated. Showing 50 of 96. Browse all 96 → or search them.
- Safety and Feasibility of the JStop™ Hemostatic Device for Nosebleeds in the Emergency DepartmentNot yet recruitingNCT07928739Not applicable
- Topical TOR-582 Treatment of Epistaxis in HHTNot yet recruitingNCT07667413Phase 11 country
- Effect of Vitamin C Administration on Intraoperative Bleeding in Patients Undergoing SinusoscopyNot yet recruitingNCT07866274Phase 2
- Comprehensive HHT Outcomes Registry of the United States (CHORUS)RecruitingNCT062592921 country
- Prospective Study of Antiplatelet and Anticoagulation Therapy in Hereditary Haemorrhagic TelangiectasiaRecruitingNCT05641142Not applicable1 country
- Algorithm-based Management to Reduce the Recurrence of GI Bleeding and Severe Epistaxis in Von Willebrand DiseaseRecruitingNCT06651255Not applicable1 country
- Outcome of Hyaluronic Acid Gel Versus Petroleum Jelly in Treatment of EpistaxisNot yet recruitingNCT07531472Not applicable
- The Efficacy of Local Application of B-sitosterol Versus Vasline in Cases of Idiopathic EpistaxisNot yet recruitingNCT07511192Phase 4
- Efficacy of Nintedanib for Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) PatientsRecruitingNCT04976036Phase 22 countries
- Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen BlockNot yet recruitingNCT07421622Not applicable
- Treatment of Nosebleeds in the Emergency Department With Powder Tranexamic AcidRecruitingNCT06997796Phase 1/21 country
- Comparison Between Nasal and Oropharyngeal Bleeding in Video Laryngoscopy and Direct Laryngoscopy for Nasal IntubationRecruitingNCT06386757Not applicable1 country
- Usage of Orange Peel Extract in Management of EpistaxisNot yet recruitingNCT06836102Not applicable
- Coblation Versus Bipolar Diathermy in Management of Refractory Idiopathic Recurrent Anterior Epistaxis in Children.Not yet recruitingNCT06651840Not applicable
- Adrenaline Nasal Pack Vs Xylometazoline Nasal Drops During Nasotracheal IntubationRecruitingNCT06801522Phase 2/31 country
- Risk Factors of Epistaxis Recurrence in AdultsNot yet recruitingNCT066570531 country
- Atmospheric Pressure and Epistaxis RelationshipRecruitingNCT065315771 country
- Tranexamic Acid Versus Blood Stopper Treatments in Epistaxis ManagementNot yet recruitingNCT06490653Phase 4
- Nasal Compression Device Study for EpistaxisRecruitingNCT05789264Not applicable1 country
- NOVAPAK Nasal Packing in Shellfish Allergic PatientsNot yet recruitingNCT05343650Phase 41 country
- Medico-economic Evaluation of Management Strategies for Severe EpistaxisRecruitingNCT05281952Not applicable1 country
- Pazopanib for the Treatment of Epistaxis in Hereditary Hemorrhagic TelangiectasiaNot yet recruitingNCT03850730Phase 1/2
- Nurse-Delivered First-Aid Education for Recurrent Pediatric EpistaxisCompletedNCT07898644Not applicable1 country
- Effects of Pazopanib on Hereditary Hemorrhagic Telangiectasia Related Epistaxis and Anemia (Paz)CompletedNCT03850964Phase 2/31 country
- A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)Active, not recruitingNCT06659640Phase 1/26 countries
- Treatment of Hereditary Hemorrhagic Telangiectasia of the Nasal Mucosa by Intranasal Bevacizumab : Search for Effective DoseCompletedNCT02157987Phase 1/21 country
- Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia PatientsTerminatedNCT04113187Phase 31 country
- Nebulized Tranexamic Acid in Sinus SurgeryCompletedNCT04905901Phase 31 country
- Sirolimus for Nosebleeds in HHTCompletedNCT05269849Phase 21 country
- A Trial of TER-1754 in Patients With Hereditary Hemorrhagic TelangiectasiaWithdrawnNCT07255846Phase 11 country
- Comparison of Nasal Endotracheal Tube and Spiral Tube for Nasotracheal Intubation in Pediatric PatientsCompletedNCT06985108Not applicable1 country
- Epistaxis in Patients Receiving Oral Anticoagulants and Antiplatelet: Prevalence Risk Factors at a Tertiary Care Hospital in NepalCompletedNCT069068611 country
- Topical 15% Trichloroacetic Acid Versus Silver Nitrate Cauterization in the Management of Idiopathic Childhood Epistaxis: A Prospective Double-Blinded, Randomized Clinical TrialCompletedNCT06836791Not applicable1 country
- Pomalidomide for the Treatment of Bleeding in HHTCompletedNCT03910244Phase 21 country
- Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy PatientsCompletedNCT05783050Not applicable1 country
- Diet and Hereditary Haemorrhagic TelangiectasiaCompletedNCT01692015Not applicable1 country
- , "Mucosal Injury During Nasotracheal Intubation for Dental Procedures in Children-does the Tube Design Matter?"CompletedNCT02517294Not applicable1 country
- Tranexamic Acid Dosage for Topical Treatment of Anterior EpistaxisCompletedNCT06183918Phase 41 country
- Cauterization of the Anterior Ethmoidal Artery by Transconjunctival ApproachStatus unknownNCT056630991 country
- Teaching First Aid and Trauma Management to School StudentsCompletedNCT05563129Not applicable1 country
- Iron Deficiency and Hereditary Haemorrhagic TelangiectasiaTerminatedNCT01908543Not applicable1 country
- Guidewire Use in Nasotracheal IntubationCompletedNCT05937516Not applicable1 country
- Xylometazoline and Cocaine for Nasal VasoconstrictionCompletedNCT05334017Phase 41 country
- Pilot Study to Assess Performance and Safety of SULFEX 13081.22 Nasal Spray in Patients With Dry or Irritated NoseStatus unknownNCT05499078Not applicable1 country
- Epinephrine Nebulization Prior to Nasotracheal IntubationCompletedNCT05738564Phase 31 country
- Management of Persistent Epistaxis Using Floseal Hemostatic MatrixCompletedNCT02488135Not applicable1 country
- Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde CholangiopancreatographyCompletedNCT05360810Not applicable1 country
- Computed Tomography-Guided Nasotracheal Intubation ProcedureCompletedNCT055257541 country
- Nasal Ointment on Epistaxis of Nasotracheal Intubation in ChildrenCompletedNCT04426409Not applicable1 country
- Effect of Nose Selection Using Rhnoscope on Epistaxis of Nasotracheal IntubationCompletedNCT04164836Not applicable1 country