Drug
Dorzolamide clinical trials
Also written Trusopt.
- studies test it
- 31
- open now
- 0
- in phase 3
- 6
- first study started
- 1999
How studies write it
Studies that test it under each name
Studies by the year they started
31 studies that test it; most in 2005 (4)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2005 | 4 |
| 2006 | 4 |
| 2007 | 2 |
| 2008 | 1 |
| 2009 | 4 |
| 2010 | 1 |
| 2011 | 3 |
| 2013 | 1 |
| 2014 | 3 |
| 2015 | 2 |
| 2016 | 1 |
| 2018 | 1 |
| 2021 | 1 |
| 2023 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 2
- Phase 2
- 3
- Phase 3
- 6
- Phase 4
- 14
- No phase
- 7
What it is tested for
Each study’s main condition, where its own words name it.
- Glaucoma
- 12
Who runs them
Industry 7 · Other 24
Aristotle University Of Thessaloniki (3) · Alcon Research (2) · Medical University of Vienna (2) · Allergan (2) · Laboratorios Poen (1) · Universitaire Ziekenhuizen KU Leuven (1) · University of Nebraska (1) · University of Florida (1)
Often tested with
Tested in the same studies.
Timolol (16) · Latanoprost (7) · Brimonidine (6) · Brinzolamide (3) · Travoprost (2) · Bimatoprost (2) · Tafluprost (1) · Dorzolamide-timolol combination (1)
Studies
Open first, then newest update. How each study uses dorzolamide is read from its arms, and is right about nine times in ten.
Testing it · 31
- Stop Retinal Ganglion Cell Dysfunction StudyTerminatedPhase 3University of MiamiNCT02390284Written as Dorzolamide
- Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and SafetyCompletedPhase 4Laboratorios PoenNCT05857267Written as Dorzolamide / Timolol Ophthalmic Solution
- How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?TerminatedPhase 4CT Glaucoma AssociatesNCT06369077Written as dorzolamide/timolol
- Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma PatientsCompletedPhase 4Universitaire Ziekenhuizen KU LeuvenNCT02053298Written as Timolol & Dorzolamide
- Circadian Rhythms of Aqueous Humor Dynamics in HumansCompletedPhase 2University of NebraskaNCT00572936Written as Dorzolamide
- Augmented Macular Pigment-containing Nutraceutical and Central Visual FunctionWithdrawnPhase 4University of the Incarnate WordNCT04676126Written as Dorzolamide Hcl 2% Oph Soln
- Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact LensesCompletedPhase 1University of FloridaNCT02852057Written as timolol maleate and dorzolamide hydrochloride
- Treatment of Cystoid Macular Edema in Patients With Retinal DegenerationCompletedPhase 4University of Illinois at ChicagoNCT00716586Written as 2% dorzolamide
- 24-hour Study of Dorzolamide/Timolol and Latanoprost/Timolol Fixed CombinationsCompletedPhase 4Aristotle University Of ThessalonikiNCT00397241Written as Drug: dorzolamide/timolol
- 24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined TherapyCompletedPhase 4Aristotle University Of ThessalonikiNCT02802137Written as tafluprost and dorzolamide/timolol
- Efficacy and Safety of Topically Applied Medical Therapy for the Treatment of Pediatric GlaucomaCompletedPhase 2Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaNCT01527682Written as Latanoprost, Dorzolamide
- Effect of Topical Aqueous Suppressants on Intraocular Gas Duration Following Pars Plana VitrectomyCompletedNot applicableMid Atlantic RetinaNCT01257698Written as Dorzolamide 2%-timolol 0.5% topical eyedrops
- Choroidal Thickness and Its Correlations With Ocular Parameters in Primary Open-angle GlaucomaCompletedPhase 4Afyon Kocatepe University HospitalNCT03966560Written as Dorzolamide (as Dorzolamide Hydrochloride) 20 Mg/mL and Timolol (as Timolol Maleate) 5 Mg/mL Eye Drops
- The Effect of Glaucoma Drops on of the Duration of a Pure Intraocular Gas BubbleCompletedNot applicableJason Hsu, MDNCT01843920Written as Timolol-dorzolamide (Glaucoma drops)
- KJ-TFC-004 Drug-drug Interaction StudyCompletedPhase 1Kukje PharmaNCT02967614Written as [B]
- A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153)CompletedPhase 3Merck Sharp & Dohme LLCNCT00546286Written as Comparator: dorzolamide HCl/timolol maleate + prostaglandin
- The DIOXXACT Trial(Diurnal IOP and OBF Xalatan vs Xalatan And Cosopt Trial)CompletedPhase 4Maisonneuve-Rosemont HospitalNCT00957190Written as Dorzolamide 20 mg and Timolol 5 mg
- Pupillary Response After Glaucoma MedicationCompletedNot applicableGlostrup University Hospital, CopenhagenNCT02522039Written as Dorzolamide
- Intraocular Pressure and Ocular Perfusion Pressure of Cosopt in Normal Tension GlaucomaCompletedNot applicableThe Catholic University of KoreaNCT01175902Written as dorzolamide/timolol
- Effects of Common Topical Glaucoma Therapy on Optic Nerve Head Blood Flow Autoregulation During Increased Arterial Blood Pressure and Artificially Elevated Intraocular Pressure in Healthy HumansWithdrawnNot applicableMedical University of ViennaNCT00275756Written as dorzolamide (drug)
See all 31 studies that test dorzolamide →
As the comparator · 4 — what is tested is compared with dorzolamide
- Comparative Study of Dorzol Eye Drops, 20 mg/ml Versus Trusopt® Eye Drops, 20 mg/mlCompletedPhase 3Jadran Galenski laboratorij d.d.NCT05973305Written as Trusopt 20 mg/ml
- MK0507A Clinical Study in Patients With Glaucoma and Ocular Hypertension (0507A-149)(COMPLETED)CompletedPhase 3Merck Sharp & Dohme LLCNCT00449956Written as Comparator: dorzolamide hydrochloride
- Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)CompletedNot applicableMassachusetts Eye and Ear InfirmaryNCT00824824Written as Dorzolamide 2%-timolol 0.5%
- Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic SolutionCompletedPhase 4Alcon, a Novartis CompanyNCT02325518Written as Dorzolamide hydrochloride 1%/Timolol maleate 0.5% ophthalmic solution
Codes
What other systems call dorzolamide · ClinicalTrials.gg INT003485
- MeSH (NLM) C062765dorzolamideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 9JDX055TW1DORZOLAMIDEConfirmed FDA, NLM, Wikidata
- RxNorm 60207Confirmed FDA, Wikidata
- Wikidata Q415401dorzolamideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C62026DorzolamideOne source FDA
- DrugBank DB00869One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C062765 | dorzolamide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 9JDX055TW1 | DORZOLAMIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 60207 | — | Confirmed FDA, Wikidata |
| Wikidata | Q415401 | dorzolamide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C62026 | Dorzolamide | One source FDA |
| DrugBank | DB00869 | — | One source Wikidata |
Also registered as dorzolamide hydrochloride (UNII QZO5366EW7 · RxNorm 236065).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.