Drug
Thalidomide clinical trials
Also written Thalomid, Kevadon and N-Phthalylglutamic Acid Imide.
- studies test it
- 323
- open now
- 19
- in phase 3
- 66
- first study started
- 1990
Keep track of what changes. Save the Thalidomide studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
312 studies that test it; most in 2002 (30)
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 2 |
| 1998 | 11 |
| 1999 | 10 |
| 2000 | 21 |
| 2001 | 29 |
| 2002 | 30 |
| 2003 | 22 |
| 2004 | 15 |
| 2005 | 18 |
| 2006 | 22 |
| 2007 | 15 |
| 2008 | 6 |
| 2009 | 6 |
| 2010 | 6 |
| 2011 | 2 |
| 2012 | 8 |
| 2013 | 10 |
| 2014 | 6 |
| 2015 | 7 |
| 2016 | 10 |
| 2017 | 11 |
| 2018 | 5 |
| 2019 | 2 |
| 2020 | 6 |
| 2021 | 2 |
| 2022 | 5 |
| 2023 | 4 |
| 2024 | 8 |
| 2025 | 5 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 29
- Phase 2
- 221
- Phase 3
- 66
- Phase 4
- 16
- No phase
- 15
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 16 · Other 307
National Cancer Institute (NCI) (24) · University of Arkansas (19) · M.D. Anderson Cancer Center (11) · Memorial Sloan Kettering Cancer Center (9) · Dana-Farber Cancer Institute (8) · SWOG Cancer Research Network (7) · Institute of Hematology & Blood Diseases Hospital, China (6) · Roswell Park Cancer Institute (5)
Often tested with
Tested in the same studies.
Dexamethasone (61) · Bortezomib (30) · Cyclophosphamide (27) · Melphalan (21) · Prednisone (17) · Doxorubicin (15) · Temozolomide (13) · Etoposide (12)
Studies
Open first, then newest update. How each study uses Thalidomide is read from its arms, and is right about nine times in ten.
Testing it · 323
- Safety and Efficacy of Hemoglobin F Inducers in Patients With Beta ThalassemiaRecruitingNot applicableRiphah International UniversityNCT07673302Written as Thalidomide
- The Efficacy of CAPCT in Patients With PTCLNot yet recruitingPhase 2The First Affiliated Hospital with Nanjing Medical UniversityNCT07746245Written as Thalidomide (100mg)
- Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid TumorsRecruitingPhase 2Sarcoma Oncology Research Center, LLCNCT07671534Written as Thalidomide
- Efficacy and Safety of Thalidomide Combined With Glutamine in the Treatment of Radiation Intestinal Injury.RecruitingPhase 2Yongquan ShiNCT06617182Written as Thalidomide
- Efficacy and Safety of Thalidomide for Pediatric PFAPA SyndromeNot yet recruitingNot applicableWenjie ZhengNCT07476625Written as Thalidomide (50mg)
- A Phase III Randomized Study of TACE Plus an Oral Triple-Agent Cocktail Versus TACE Plus First-Line Targeted Immunotherapy in Unresectable Hepatocellular CarcinomaNot yet recruitingPhase 2/3Shanghai Zhongshan HospitalNCT07309419Written as Thalidomide (drug)
- Thalidomide for the Symptomatic Large Granular Lymphocytic LeukemiaRecruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT06530576Written as Thalidomide and methotrexate
- Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCHRecruitingPhase 2Cancer Institute and Hospital, Chinese Academy of Medical SciencesNCT07187193Written as Thalidomide (100mg)
- Aponermin-Based Bridging Therapy Prior to CAR-T Infusion in Relapsed/Refractory Multiple Myeloma Patients With Extramedullary DiseaseRecruitingNot applicableInstitute of Hematology & Blood Diseases Hospital, ChinaNCT06793475Written as Thalidomide
- Thalidomide Enhances Clinical Efficacy of Cetuximab Combined With Standard Chemotherapy for Left Colorectal CancerRecruitingPhase 2Xinqiao Hospital of ChongqingNCT06279351Written as Thalidomide+cetuximab+FOLFOX/FOLFIRI
- Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta ThalassemiaRecruitingPhase 2National Institute of Blood and Marrow Transplant (NIBMT), PakistanNCT06490627Written as Thalidomide
- Thalidomide Versus Argon Plasma Coagulation in Gastric Antral Vascular Ectasia(GAVE)-Related Anaemia in Cirrhosis (TAG Trial)Not yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT06772480Written as Thalidomide
- Thalidomide Prevention or Treatment of Camrelizumab-induced Reactive Cutaneous Capillary Endothelial Proliferation (RCCEP)RecruitingPhase 2Henan Cancer HospitalNCT06231680Written as Thalidomide 50mg
- A Study of Camrelizumab Combined With Chemotherapy ± Thalidomide in First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC)Not yet recruitingPhase 4Tongji UniversityNCT06276933Written as Camrelizumab + chemotherapy+Thalidomide
- The Therapeutic Effect of Thalidomide in SyringomyeliaRecruitingPhase 2Xuanwu Hospital, BeijingNCT06268093Written as Thalidomide
- Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic CancerRecruitingPhase 3Fudan UniversityNCT06017284Written as Thalidomide
- Selinexor in Combination With Immunomodulator （Thalidomide/Pomalidomide/Lenalidomide）in RRMMRecruitingPhase 2Juan DuNCT04941937Written as Thalidomide
- TPM Regimen (Thalidomide, Prednisone and Methotrexate) in LGLLRecruitingPhase 2/3Institute of Hematology & Blood Diseases Hospital, ChinaNCT04453345Written as thalidomide + prednisone + methotrexate
- A Prospective Multicenter Phase 2 Study of FCR/BR Alternating With Ibrutinib in Treatment-naive Patients With CLLRecruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT03980002Written as Ibrutinib and Thalidomide
- 2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance TherapyActive, not recruitingPhase 2University of ArkansasNCT03004287Written as Thalidomide
See all 323 studies that test Thalidomide →
Given in every arm · 19 — Thalidomide is usual care beside what is tested
- Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent β-ThalassemiaRecruitingPhase 3Khyber Medical University PeshawarNCT07884773Written as Thalidomide
- Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS TumorsRecruitingPhase 2Medical University of ViennaNCT01356290Written as Thalidomide
- CURATE.AI Optimized Modulation for Multiple MyelomaRecruitingPhase 2/3National University Hospital, SingaporeNCT03759093Written as Thalidomide
- Daratumumab-Based Therapy for the Treatment of Newly Diagnosed Multiple Myeloma With Kidney FailureTerminatedPhase 2Emory UniversityNCT04352205Written as Thalidomide
- MMVAR - Velcade: Study of Velcade for the Treatment of Myeloma Patients After Autologous TransplantationTerminatedPhase 3European Society for Blood and Marrow TransplantationNCT00256776Written as Thalidomide
- S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic AmyloidosisCompletedPhase 2SWOG Cancer Research NetworkNCT00064337Written as thalidomide
- Phase II Study of RT-PEPC in Relapsed Mantle Cell LymphomaCompletedPhase 2Weill Medical College of Cornell UniversityNCT00151281Written as Thalidomide
- Modified Bortezomib-based Combination Therapy for Multiple MyelomaStatus unknownPhase 4Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineNCT02559154Written as Thalidomide
- Docetaxel, Thalidomide, Prednisone, and Bevacizumab to Treat Metastatic Prostate CancerCompletedPhase 2National Cancer Institute (NCI)NCT00089609Written as Thalidomide
- Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body WallTerminatedPhase 2National Cancer Institute (NCI)NCT00089544Written as Thalidomide
- Clarithromycin Plus CTd Regimen for Patients With Newly Diagnosed Multiple MyelomaStatus unknownPhase 3Jinling Hospital, ChinaNCT02248428Written as Thalidomide
- Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics of Simmitecan Monotherapy and Combination in Patients With Advanced Solid TumorsStatus unknownPhase 1Haihe Biopharma Co., Ltd.NCT02870036Written as Thalidomide
- Tandem Auto Transplantation in Myeloma Patients With <12 Months of Prior TreatmentTerminatedPhase 2University of IowaNCT01548573Written as Thalidomide
- A Study of Thalidomide Plus Dexamethasone (Thal-Dex) Versus DOXIL plusThalidomide Plus Dexamethasone (DOXIL -Thal-Dex) in Patients With Newly Diagnosed Multiple MyelomaCompletedPhase 3Johnson & Johnson Pharmaceutical Research & Development, L.L.C.NCT00097981Written as Thalidomide
- The Effects of Huang-Lian-Jie-Du-Tang（HLJDT) on the Survival of Patients With Multiple Myeloma in Maintain TherapyStatus unknownPhase 1Wuhan UniversityNCT02467647Written as Thalidomide
- Effects of Exercise in Combination With Epoetin AlfaCompletedNot applicableUniversity of ArkansasNCT00577096Written as Thalidomide
- Filgrastim in Treating Patients With Bortezomib-, Carfilzomib-, or IMID-Refractory Multiple MyelomaTerminatedEarly Phase 1Washington University School of MedicineNCT01537861Written as Thalidomide
- Thalidomide With or Without Fludarabine in Treating Patients With Hematologic CancerTerminatedPhase 2National Cancer Institute (NCI)NCT00009984Written as thalidomide
- VELCADE-Thalidomide-Dexamethasone (VTD) vs Thalidomide-Dexamethasone (TD) Incorporated Into Double Autotransplantation for Untreated Multiple Myeloma (MM)Status unknownPhase 3Michele CavoNCT01134484Written as Thalidomide
As the comparator · 7 — what is tested is compared with Thalidomide
- Efficacy and Safety Study of Dovramilast in People With Leprosy Type 2 ReactionRecruitingPhase 2Medicines Development for Global HealthNCT07172659Written as Thalidomide
- Bevacizumab in the Treatment of HHTRecruitingPhase 2Second Affiliated Hospital, Zhejiang University, School of MedicineNCT07828015Written as Thalidomide (50mg)
- Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple MyelomaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT00602641Written as Thalidomide
- Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) AmyloidosisTerminatedPhase 3Millennium Pharmaceuticals, Inc.NCT01659658Written as Thalidomide
- Comparison Of Efficacy And Safety Of Thalidomide Vs Hydroxyurea In Thalassemia Patients: A Single-Centre Pilot Study.CompletedPhase 2National Institute of Blood and Marrow Transplant (NIBMT), PakistanNCT06239389Written as Thalidomide 100mg
- Study to Determine Efficacy and Safety of Lenalidomide Plus Low-dose Dexamethasone Versus Melphalan, Prednisone, Thalidomide in Patients With Previously Untreated Multiple MyelomaCompletedPhase 3CelgeneNCT00689936Written as Melphalan, Prednisone and Thalidomide
- A Study of Tegafur Combined With Temozolomide Versus Tegafur Combined With Temozolomide and Thalidomide in Subjects With Advanced Extrapancreatic Neuroendocrine TumorStatus unknownPhase 2Chinese Academy of Medical SciencesNCT03204032Written as Thalidomide
Codes
What other systems call Thalidomide · ClinicalTrials.gg INT008299
- MeSH (NLM) D013792ThalidomideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 4Z8R6ORS6LTHALIDOMIDEConfirmed FDA, NLM, Wikidata
- RxNorm 10432Confirmed FDA, Wikidata
- Wikidata Q203174thalidomideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C870ThalidomideOne source FDA
- DrugBank DB01041One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D013792 | Thalidomide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 4Z8R6ORS6L | THALIDOMIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10432 | — | Confirmed FDA, Wikidata |
| Wikidata | Q203174 | thalidomide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C870 | Thalidomide | One source FDA |
| DrugBank | DB01041 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.